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CAS 84000-11-3
:N-[(9H-Fluoren-9-ilmetossi)carbonil]-N-metil-L-valina
Descrizione:
N-[(9H-Fluoren-9-ilmetossi)carbonil]-N-metil-L-valina, comunemente noto come Fmoc-N-metil-L-valina, è un composto chimico ampiamente utilizzato nella sintesi di peptidi come gruppo protettore per aminoacidi. Il gruppo Fmoc, derivato dal fluorenilmetossicarbonile, fornisce stabilità durante il processo di sintesi e può essere facilmente rimosso in condizioni basiche, consentendo ulteriori reazioni. Questo composto presenta un residuo di valina, che è un aminoacido essenziale noto per le sue proprietà idrofobiche, contribuendo alle caratteristiche generali dei peptidi in cui è incorporato. La presenza del gruppo N-metil aumenta il volume sterico e può influenzare la conformazione dei peptidi risultanti. Fmoc-N-metil-L-valina è tipicamente utilizzato nella sintesi di peptidi in fase solida (SPPS), dove aiuta nell'assemblaggio selettivo delle catene peptidiche. La sua solubilità in solventi organici e stabilità in varie condizioni di reazione lo rendono un reagente prezioso nel campo della chimica organica e medicinale. Come per molte sostanze chimiche, una corretta manipolazione e precauzioni di sicurezza sono essenziali a causa dei potenziali pericoli associati al suo uso.
Formula:C21H23NO4
InChI:InChI=1/C21H23NO4/c1-13(2)19(20(23)24)22(3)21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,12H2,1-3H3,(H,23,24)/t19-/m0/s1
InChI key:InChIKey=YCXXXPZNQXXRIG-IBGZPJMESA-N
SMILES:C(OC(N([C@@H](C(C)C)C(O)=O)C)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2
Sinonimi:- (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl](methyl)amino)-3-methylbutanoic acid
- (2S)-2-[9H-Fluoren-9-ylmethoxycarbonyl(methyl)amino]-3-methylbutanoic acid
- <span class="text-smallcaps">L</span>-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
- Fmoc-N-Me-Val-OH
- N-(9-Fluorenylmethoxycarbonyl)-N-methylvaline
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-<span class="text-smallcaps">L</span>-valine
- N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valine
- N-alpha-(9-fluorenylmethyloxycarbonyl)-N-alpha-Methyl-L-valine
- L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
- FMOC-N-ME-VAL 98.5+%
- FMOC-L-MEVAL-OH
- FMOC-N-METHYL-L-VALINE
- FMOC-N-ALPHA-METHYL-L-VALINE
- FMOC-MEVAL-OH
- FMOC-N-ME-L-VAL-OH
- FMOC-N-ME-VALINE
- N-(9-Fluorenylmethyloxycarbonyl)-N-methyl-L-valine
- N-ALPHA(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-L-VALINE
- Vedi altri sinonimi
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N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valine
CAS:Formula:C21H23NO4Purezza:>98.0%(HPLC)(T)Colore e forma:White to Almost white powder to crystalPeso molecolare:353.42N-Fmoc-N-methyl-L-valine, 95%
CAS:N-Fmoc-N-methyl-L-valine is used as enzyme substrates and reagents, culture media additives, dyes, stains and indicators. It is also involved in the preparation of N-methylated peptides. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some docuFormula:C21H23NO4Purezza:95%Peso molecolare:353.42Fmoc-N-Me-Val-OH
CAS:The acid fluoride of this sterically hindered amino acid could be coupled to N-methylated amino acids in HFIP at 55°C.Formula:C21H23NO4Purezza:99.7%Colore e forma:WhitePeso molecolare:353.42Fmoc-N-Me-Val-OH
CAS:Formula:C21H23NO4Purezza:(HPLC) ≥ 98.0%Colore e forma:White to light beige powderPeso molecolare:353.41Fmoc-N-methyl-L-valine
CAS:Fmoc-N-methyl-L-valineFormula:C21H23NO4Purezza:>98%Colore e forma:SolidPeso molecolare:353.41162Fmoc-N-Me-Val-OH
CAS:Fmoc-N-Me-Val-OH is a modified peptide.Formula:C21H23NO4Colore e forma:SolidPeso molecolare:353.4116N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valine
CAS:Formula:C21H23NO4Purezza:97%Colore e forma:SolidPeso molecolare:353.4116Ref: IN-DA005235
1g24,00€250mg24,00€5g31,00€10g50,00€25g78,00€50g118,00€100g195,00€250g530,00€500g771,00€Fmoc-N-Me-Val-OH
CAS:M03379 - Fmoc-N-Me-Val-OH
Formula:C21H23NO4Purezza:97%Colore e forma:SolidPeso molecolare:353.418Fmoc-N-methyl-L-valine
CAS:Fmoc-N-methyl-L-valine is a synthetic immunosuppressant that acts by inhibiting the production of cytokines and other inflammatory mediators. It binds to the enzyme cyclooxygenase, which is involved in the synthesis of prostaglandins and thromboxanes. Fmoc-N-methyl-L-valine has been shown to be effective against gram-positive bacteria. This compound also inhibits xanthine oxidase and may act as an analog for azathioprine, which is used in the treatment of autoimmune diseases such as rheumatoid arthritis. The reaction mechanism for this compound is not well understood but appears to involve a nucleophilic attack on a benzoquinoneiminium cation formed from the attack on an electron deficient benzene ring with a triphosgene electrophile.Formula:C21H23NO4Purezza:Min. 95%Peso molecolare:353.41 g/mol
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