CAS 85-61-0

Coenzima A

Descrizione:

Coenzima A (CoA) è un cofattore vitale in varie reazioni biochimiche, principalmente coinvolto nel metabolismo degli acidi grassi e dei carboidrati. È una molecola complessa composta da adenosina, acido pantotenico (vitamina B5) e un gruppo mercaptoetilamina. CoA svolge un ruolo cruciale nella formazione di acetil-CoA, che è un substrato chiave per il ciclo dell'acido citrico, facilitando la produzione di energia nelle cellule. La sostanza è caratterizzata dalla sua capacità di formare legami tioestere, essenziali per l'attivazione dei gruppi acilici nelle vie metaboliche. Coenzima A è solubile in acqua e presenta un alto grado di reattività grazie alla presenza del suo gruppo tiolico, permettendole di partecipare a varie reazioni enzimatiche. La sua struttura le consente di fungere da trasportatore per i gruppi acilici, rendendola indispensabile nella sintesi e degradazione degli acidi grassi e nel metabolismo degli aminoacidi. In generale, Coenzima A è fondamentale per il metabolismo energetico cellulare e la sintesi di biomolecole importanti.

Formula: C₂₁H₃₆N₇O₁₆P₃S

InChI: InChI=1S/C21H36N7O16P3S/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35)/t11-,14-,15-,16+,20-/m1/s1

InChI key: InChIKey=RGJOEKWQDUBAIZ-IBOSZNHHSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OCC([C@H](C(NCCC(NCCS)=O)=O)O)(C)C)(=O)O)(=O)O)[C@H]1OP(=O)(O)O

Sinonimi:

• <span class="text-smallcaps">D</span>-Coenzyme A
• Adenosine 5'-(trihydrogen diphosphate) 3'-(dihydrogen phosphate) P'-[(R)-3-hydroxy-4-[[3-[(2-mercaptoethyl)amino]-3-oxopropyl]amino]-2,2-dimethyl-4-oxobutyl] ester
• Adenosine 5'-(trihydrogen diphosphate), 3'-(dihydrogen phosphate), P'-[3-hydroxy-4-[[3-[(2-mercaptoethyl)amino]-3-oxopropyl]amino]-2,2-dimethyl-4-oxobutyl] ester, (R)-
• Aluzime
• COA
• CoASH
• Coa-Sh
• Coalip
• Coenzym A
• Coenzyme A Free Acid From Yeast
• Coenzyme A Hydrate
• Coenzyme A, free acid, lyophilized, 75%
• Coenzyme A, free acid, lyophilized, min. 75% (enzym.)
• Coenzyme ASH
• Coenzyme a, free acid
• D-Coenzyme A
• Lucina
• Reduced CoA
• Thiol-CoA
• [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl dihydrogen diphosphate (non-preferred name)
• [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3S)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl dihydrogen diphosphate (non-preferred name)
• [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl 3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl dihydrogen diphosphate (non-preferred name)
• coenzima A

Coenzyme A

CAS: 85-61-0

Coenzyme A

Purezza: ≥90%

Peso molecolare: 767.53g/mol

Ref: 54-BUP15611

Coenzyme A Free Acid

CAS: 85-61-0

Coenzyme A Free Acid

Formula: C₂₁H₃₆N₇O₁₆P₃S

Purezza: ≥95.0%

Peso molecolare: 767.53g/mol

Ref: 54-BIA0812

Coenzyme A hydrate

CAS: 85-61-0

Formula: C₂₁H₃₆N₇O₁₆P₃S·xH₂O

Purezza: ≥ 90.0%

Colore e forma: White to off-white or pale yellow powder

Peso molecolare: 767.53 (anhydrous)

Ref: 7W-GK0114

Coenzyme A

CAS: 85-61-0

Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.

Formula: C₂₁H₃₆N₇O₁₆P₃S

Purezza: 93.84%

Colore e forma: Solid

Peso molecolare: 767.53

Ref: TM-T10857

Coenzyme A free acid

CAS: 85-61-0

Formula: C21H36N7O16P3S

Purezza: >94%

Colore e forma: Solid

Peso molecolare: 767.54

Ref: 48-19-1001

Coenzyme A hydrate

CAS: 85-61-0

Coenzyme A hydrate is essential in the metabolism of fatty acids and the synthesis of acetyl-CoA. It is also employed in pharmaceutical applications, especially in drug development and formulation. Its distinctive properties improve drug solubility and bioavailability, making it an essential component in the creation of therapeutic agents.

Formula: C₂₁H₃₆N₇O₁₆P₃S·xH₂O

Purezza: (Enzymatic) Min. 75%

Colore e forma: White Off-White Slightly Yellow Powder

Peso molecolare: 767.54 g/mol

Ref: 3D-NC45965

Coenzyme A Free Acid extrapure, 90%

CAS: 85-61-0

Formula: C₂₁H₃₆N₇O₁₆P₃S

Purezza: min. 90%

Colore e forma: Almost white to slightly yellowish, Lyophilized powder

Peso molecolare: 767.54

Ref: SR-40804

Coenzyme A, Free Acid

CAS: 85-61-0

Purezza: 95%

Peso molecolare: 767.115

Ref: 10-C300023

Coenzyme A S-Pyrazinecarboxylate Trisodium Salt

Prodotto controllato

CAS: 85-61-0

Applications Coenzyme A S-Pyrazinecarboxylate is a derivative of Coenzyme A (C636400); a cofactor in enzymatic acetyl transfer reactions. It is the source of the phosphopantetheine group that is added as a prosthetic group to proteins such as acyl carrier protein and formyltetrahydrofolate dehydrogenase.
References Strickland K.C. et al.: J. Biol. Chem., 285, 1627 (2010); Elovson J. et al.: J. Biol. Chem., 243, 3603 (1968)

Formula: C₂₆H₃₅N₉Na₃O₁₇P₃S

Colore e forma: Neat

Peso molecolare: 939.56

Ref: TR-C636415