CAS 877636-42-5

Formula: C17H11N3O6S

InChI: InChI=1S/C17H11N3O6S/c21-14-8-13(10-27-17-18-6-1-7-19-17)25-9-15(14)26-16(22)11-2-4-12(5-3-11)20(23)24/h1-9H,10H2

InChI key: UASIRTUMPRQVFY-UHFFFAOYSA-N

SMILES: C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)[N+](=O)[O-]

4-Oxo-6-((Pyrimidin-2-Ylthio)Methyl)-4H-Pyran-3-Yl 4-Nitrobenzoate

CAS: 877636-42-5

4-Oxo-6-((Pyrimidin-2-Ylthio)Methyl)-4H-Pyran-3-Yl 4-Nitrobenzoate

Formula: C₁₇H₁₁N₃O₆S

Purezza: 97%

Peso molecolare: 385.35

Ref: 54-OR1025978

ML221

CAS: 877636-42-5

ML221

Formula: C₁₇H₁₁N₃O₆S

Purezza: 99.5%

Peso molecolare: 385.35

Ref: 54-BUP05998

ML221

CAS: 877636-42-5

Formula: C₁₇H₁₁N₃O₆S

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 385.3507

Ref: IN-DA01ENZJ

ML221

CAS: 877636-42-5

ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in

Formula: C₁₇H₁₁N₃O₆S

Purezza: 97.74% - 99.67%

Colore e forma: White Solid

Peso molecolare: 385.35

Ref: TM-T4390

4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate

CAS: 877636-42-5

4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate

Formula: C₁₇H₁₁N₃O₆S

Purezza: 97%

Peso molecolare: 385.35

Ref: IN-DG00775269

4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate

CAS: 877636-42-5

Purezza: 97%

Peso molecolare: 385.3500061

Ref: 10-F867086

ML 221

CAS: 877636-42-5

ML 221 is a monoclonal antibody that specifically binds to follicular growth factor (FGF). It blocks the interaction between FGF and its receptor, thereby inhibiting follicular growth. The effects of ML 221 in vivo have been demonstrated in wild-type mice. In these mice, ML 221 inhibited the proliferation of granulosa cells, which are cells found in the ovaries responsible for producing estrogen. This effect was also seen in human liver cells and endothelial cells. Additionally, ML 221 has been shown to inhibit mitochondrial membrane potential and endothelial cell proliferation. Finally, ML 221 has been shown to decrease the severity of proliferative diabetic retinopathy (PDR) by blocking FGF receptors on blood vessels that line the retina. ML 221 is an experimental drug that inhibits follicular growth and can be used to treat PDR.

Formula: C₁₇H₁₁N₃O₆S

Purezza: Min. 95%

Peso molecolare: 385.35 g/mol

Ref: 3D-CKB63642