CAS 894783-71-2

Formula: C30H31N5O4

InChI: InChI=1S/C30H31N5O4/c1-33-14-16-35(17-15-33)19-26(36)34(2)23-11-9-22(10-12-23)31-28(20-6-4-3-5-7-20)27-24-13-8-21(30(38)39)18-25(24)32-29(27)37/h3-13,18,32,37H,14-17,19H2,1-2H3,(H,38,39)

InChI key: SDJMWYVJAVLZEG-UHFFFAOYSA-N

SMILES: CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)O)O

Nintedanib Acid

CAS: 894783-71-2

Lactams, nesoi

Formula: C₃₀H₃₁N₅O₄

Colore e forma: Pale Yellow Solid

Peso molecolare: 525.2376

Ref: 45-1A05640

Nintedanib Impurity 6-13C-d3

CAS: 894783-71-2

Formula: C₂₉₁₃CH₂₈D₃N₅O₄

Colore e forma: Yellow Solid

Peso molecolare: 529.62

Ref: 4Z-N-066054

BIBF 1202

CAS: 894783-71-2

BIBF 1202

Formula: C₃₀H₃₁N₅O₄

Purezza: 98.5%

Peso molecolare: 525.6

Ref: 54-BUP10984

Nintedanib Impurity 6 Ditrifluoroacetate

CAS: 894783-71-2

Formula: C₃₀H₃₁N₅O₄·2C₂HF₃O₂

Peso molecolare: 525.61 2*114.02

Ref: 4Z-N-066094

Nintedanib Impurity 6

CAS: 894783-71-2

Formula: C₃₀H₃₁N₅O₄

Colore e forma: Yellow Solid

Peso molecolare: 525.61

Ref: 4Z-N-066015

(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid

CAS: 894783-71-2

Formula: C₃₀H₃₁N₅O₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 525.5982

Ref: IN-DA00GU1U

Nintedanib Carboxylic Acid

CAS: 894783-71-2

Formula: C₃₀H₃₁N₅O₄

Colore e forma: Neat

Peso molecolare: 525.6

Ref: TR-N478285

BIBF 1202

CAS: 894783-71-2

Formula: C₃₀H₃₁N₅O₄

Peso molecolare: 525.6

Ref: BE-RMCN104015

BIBF 1202

CAS: 894783-71-2

Purezza: 98%

Peso molecolare: 525.609

Ref: 10-F987629

BIBF 1202

CAS: 894783-71-2

BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).

Formula: C₃₀H₃₁N₅O₄

Purezza: 98.69%

Colore e forma: Solid

Peso molecolare: 525.5982

Ref: TM-TQ0321

BIBF 1202

CAS: 894783-71-2

(Z)-3-(((4-(N-Methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid

Formula: C₃₀H₃₁N₅O₄

Purezza: 97%

Peso molecolare: 525.6

Ref: IN-DG629200

(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic Acid-D3

Prodotto controllato

CAS: 894783-71-2

Applications (3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic Acid-D3 is an intermediate used in the synthesis of Nintedanib Demethyl-O-glucuronic Acid-d3 (N478297), which is an isotopic analog of Nintedanib Demethyl-O-glucuronic Acid (N478295), a metabolite of the drug Nintedanib (N478290).
References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)

Formula: C₃₀D₃H₂₈N₅O₄

Colore e forma: Neat

Peso molecolare: 528.617

Ref: TR-D454387

Nintedanib Carboxylic Acid

CAS: 894783-71-2

Formula: C₃₀H₃₁N₅O₄

Peso molecolare: 525.61

Ref: ST-EA-CP-N24004

BIBF 1202

CAS: 894783-71-2

BIBF 1202 is a potent inhibitor of phospholipase A2, prostaglandin synthase and cyclooxygenase-2. It inhibits the production of arachidonic acid from membrane phospholipids and is used in cancer research. BIBF 1202 has been shown to have anti-tumour activity in a number of animal models, including human liver cancer cells. This molecule has also been shown to inhibit the activation of nuclear factor kappa B (NF-κB), which is involved in carcinogenesis.

Formula: C₃₀H₃₁N₅O₄

Purezza: Min. 95%

Peso molecolare: 525.6 g/mol

Ref: 3D-UKB78371