CAS 894804-07-0

Formula: C18H20N4O4

InChI: InChI=1S/C18H20N4O4/c1-4-26-18-13(10-19)14(20)9-16(22-18)21-17(23)8-11-7-12(24-2)5-6-15(11)25-3/h5-7,9H,4,8H2,1-3H3,(H3,20,21,22,23)

InChI key: KQMPRSZTUSSXND-UHFFFAOYSA-N

SMILES: CCOC1=C(C(=CC(=N1)NC(=O)CC2=C(C=CC(=C2)OC)OC)N)C#N

N-(4-Amino-5-Cyano-6-Ethoxypyridin-2-Yl)-2-(2,5-Dimethoxyphenyl)Acetamide

CAS: 894804-07-0

N-(4-Amino-5-Cyano-6-Ethoxypyridin-2-Yl)-2-(2,5-Dimethoxyphenyl)Acetamide

Formula: C₁₈H₂₀N₄O₄

Purezza: 98%

Peso molecolare: 356.38

Ref: 54-OR1024296

JNK Inhibitor VIII

CAS: 894804-07-0

JNK Inhibitor VIII

Formula: C₁₈H₂₀N₄O₄

Purezza: 98.5%

Colore e forma: Solid

Peso molecolare: 356.38

Ref: 54-BUP03066

N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide

CAS: 894804-07-0

Formula: C₁₈H₂₀N₄O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 356.3758

Ref: IN-DA0087RS

N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide

CAS: 894804-07-0

N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide

Formula: C₁₈H₂₀N₄O₄

Purezza: 98%

Peso molecolare: 356.38

Ref: IN-DG00792759

JNK Inhibitor VIII

CAS: 894804-07-0

JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2,

Formula: C₁₈H₂₀N₄O₄

Purezza: 98.93%

Colore e forma: Solid

Peso molecolare: 356.38

Ref: TM-T7677

JNK Inhibitor VIII

CAS: 894804-07-0

Purezza: 98%

Peso molecolare: 356.148

Ref: 10-F840736

JNK Inhibitor VIII

Prodotto controllato

CAS: 894804-07-0

Applications JNK Inhibitor VIII is an inhibitor shown to suppress apoptosis, caspase cleavage, and cytochrome C release.

Formula: C₁₈H₂₀N₄O₄

Colore e forma: Neat

Peso molecolare: 356.376

Ref: TR-J211273

JNK Inhibitor VIII

CAS: 894804-07-0

JNK inhibitor VIII is a potent, selective and cell-permeable JNK inhibitor that is effective in inhibiting the activation of pro-inflammatory genes. It has been shown to inhibit the proliferation and induce apoptosis in leukemia cells, as well as blocking the growth of primary human prostate cancer cells. JNK inhibitor VIII blocks ubiquitin ligases involved in protein degradation and mitochondrial membrane potential, which induces reactive oxygen species (ROS) production by mitochondria. This leads to an increase in cytosolic Ca2+, c-jun phosphorylation, and potential drug target for cancer therapy.

Formula: C₁₈H₂₀N₄O₄

Purezza: Min. 95%

Peso molecolare: 356.38 g/mol

Ref: 3D-UKB80407