CAS: 934660-93-2 - Cobimetinib

Formula: C₂₁H₂₁F₃IN₃O₂

InChI: InChI=1S/C21H21F3IN3O2/c22-14-6-5-13(19(18(14)24)27-16-7-4-12(25)9-15(16)23)20(29)28-10-21(30,11-28)17-3-1-2-8-26-17/h4-7,9,17,26-27,30H,1-3,8,10-11H2/t17-/m0/s1

InChI key: InChIKey=BSMCAPRUBJMWDF-KRWDZBQOSA-N

SMILES: O=C(C1=CC=C(F)C(F)=C1NC2=CC=C(I)C=C2F)N3CC(O)(C3)C4NCCCC4

Sinonimi:

• (S)-(3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)methanone
• Gdc-0973
• Methanone, [3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl][3-hydroxy-3-(2S)-2-piperidinyl-1-azetidinyl]-
• Rg 7421
• Rg7421
• Xl 518
• [3,4-Difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone
• [3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl][3-hydroxy-3-(2S)-2-piperidinyl-1-azetidinyl]methanone

Cobimetinib-d9

CAS: 934660-93-2

• Formula: C₂₁H₁₂D₉F₃IN₃O₂
• Peso molecolare: 540.37

Cobimetinib

CAS: 934660-93-2

Cobimetinib (GDC-0973) is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). …

• Formula: C₂₁H₂₁F₃IN₃O₂
• Purezza: 100%
• Colore e forma: Solid
• Peso molecolare: 531.31

Cobimetinib

CAS: 1369665-02-0 934660-93-2

• Formula: C₂₁H₂₁F₃IN₃O₂
• Peso molecolare: 531.32

XL518

CAS: 934660-93-2

Applications A potent, selective, orally bioavailable inhibitor of MEK1, a component of the RAS/RAF/MEK/ERK pathway. …

• Formula: C₂₁H₂₁F₃IN₃O₂
• Colore e forma: White To Off-White
• Peso molecolare: 531.31

Cobimetinib

CAS: 934660-93-2

Inhibitor of MEK kinase

• Formula: C₂₁H₂₁F₃IN₃O₂
• Purezza: Min. 95%
• Colore e forma: White Powder
• Peso molecolare: 531.31 g/mol

XL518-d4

CAS: 934660-93-2

• Formula: C₂₁H₁₇D₄F₃IN₃O₂
• Peso molecolare: 535.335

XL518

CAS: 934660-93-2

• Formula: C₂₁H₂₁F₃IN₃O₂
• Purezza: 98+%
• Colore e forma: Solid
• Peso molecolare: 531.3100