CAS 97240-79-4

Topiramato

Descrizione:

Topiramato è un monosaccaride sostituito da sulfamato che viene utilizzato principalmente come anticonvulsivante e per la prevenzione dell'emicrania. La sua formula chimica è C12H21N3O8S e presenta una struttura unica che include un gruppo sulfamato, che contribuisce alle sue proprietà farmacologiche. Topiramato è noto per la sua capacità di inibire alcuni percorsi dei neurotrasmettitori, in particolare quelli che coinvolgono il glutammato, e aumenta l'attività dell'acido gamma-aminobutirrico (GABA), un importante neurotrasmettitore inibitorio nel cervello. Questo meccanismo d'azione duale lo rende efficace nel controllare le crisi e nel prevenire gli attacchi di emicrania. La sostanza viene tipicamente somministrata per via orale ed è ben assorbita nel tratto gastrointestinale. Topiramato è anche associato a una serie di effetti collaterali, tra cui compromissione cognitiva, perdita di peso e possibile acidosi metabolica. Il suo profilo di sicurezza ed efficacia lo ha reso un farmaco ampiamente prescritto in neurologia e psichiatria. Come per qualsiasi farmaco, è importante che i pazienti discutano i potenziali rischi e benefici con il proprio medico.

Formula: C₁₂H₂₁NO₈S

InChI: InChI=1/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9?,12+/m0/s1

InChI key: InChIKey=KJADKKWYZYXHBB-XBWDGYHZSA-N

SMILES: C(OS(N)(=O)=O)[C@]12[C@]([C@]3([C@@](CO1)(OC(C)(C)O3)[H])[H])(OC(C)(C)O2)[H]

Sinonimi:

• 2,3:4,5-Bis-O-(1-methylethylidene) β-<span class="text-smallcaps">D</span>-fructopyranose sulfamate
• 2,3:4,5-Bis-O-(1-methylethylidene) β-D-fructopyranose sulfamate
• 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate
• 5H-Bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran, β-<span class="text-smallcaps">D</span>-fructopyranose deriv.
• Epitoma
• Epitomax
• McN 4853
• Qudexy XR
• Rwj 17021
• Sincronil
• TPM
• Toiramate
• Topamac
• Topamax
• Topimax
• Topina
• Topiragen
• Topomax
• Tracrium
• Trokendi XR
• β-<span class="text-smallcaps">D</span>-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate
• β-<span class="text-smallcaps">D</span>-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
• β-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate
• β-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
• Topiramate
• 5H-Bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran, β-D-fructopyranose deriv.
• 2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose sulfamate
• Topiramato [INN-Spanish]
• 1-O-Sulfamoyl-2-O,3-O:4-O,5-O-diisopropylidene-β-D-fructopyranose
• Topiramate Synonyms Topamax
• TopiramateTopamax
• Topiramate solution
• 2,3:4,5-Di-O-isopropylidene-β-D-fructopyranoside sulfamate
• 2,3:4,5-Di-O-isopropylidene-b-D-fructopyranosidesulfamate
• Topiramate (150 mg)
• Tipiramato [Spanish]
• 2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranose sulfamate
• RWJ-17021-000
• TopiraMate(McN-4853,RWJ-17021,TopaMax)
• Tipiramate [French]
• Topiramic acid
• .beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
• McN 4853, RWJ 17021, Topamax, 2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate
• 1-O-Sulfamoyl-2-O,3-O:4-O,5-O-bis(1-methylethylidene)-β-D-fructopyranose
• TopiraMate API
• 2,3:4,5-Bis-O-(1-methylethylidene)--D-fuctopyranose Sulfamate, McN-4853, RWJ-17021-000, Topamax
• ((3aS,5aR,8aR,8bS)-2,2,7,7-tetraMethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)Methyl sulfaMate
• ((3AS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl
• 2,3:4,5-Bis-O-(1-Methylethylidene)-β-D-fuctopyranose 1-SulfaMate
• Topiramatum [INN-Latin]
• TopiriMate-d12
• 2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-B-D-FUCTO-PYRANOSE SULFAMATE
• Topiramate [USAN:BAN:INN]
• PHARMACEUTICAL RAW MATERIAL: TOPIRAMATEUSP
• topiramatum [Latin]
• 2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranossulfamate
• 2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-36-D-FRUCTO-PYRANOSE SULFAMATE
• 2,3:4,5-Di-O-isopropylidene-b-D-fructopyranose sulfamate
• 2,3:4,5-Di-O-isopropylidene-1-O-sulfamoyl-beta-D-fructopyranose
• Topiramate, >=98%
• 2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-BETA-D-FUCTOPYRANOSE SULFAMATE

Topiramate

CAS: 97240-79-4

Formula: C₁₂H₂₁NO₈S

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 339.36

Ref: 3B-T2755

TOPIRAMATE CRS

CAS: 97240-79-4

TOPIRAMATE CRS

Colore e forma: Powder

Ref: 41-Y0002134

Topiramate

CAS: 97240-79-4

Topiramate

Formula: C₁₂H₂₁NO₈S

Purezza: 99.9%

Colore e forma: White. To. Off-White

Peso molecolare: 339.09879

Ref: 47-1322

Topiramate impurity A

CAS: 97240-79-4

Topiramate impurity A

Colore e forma: White. To. Off-White

Ref: 47-1323

Topiramate

CAS: 97240-79-4

Sulfonamides used as drugs

Formula: C₁₂H₂₁NO₈S

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 339.09879

Ref: 45-1672206

Topiramate

CAS: 97240-79-4

Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.

Formula: C₁₂H₂₁NO₈S

Purezza: 99.79% - 99.92%

Colore e forma: Solid

Peso molecolare: 339.36

Ref: TM-T0675

Topiramate

CAS: 97240-79-4

Formula: C₁₂H₂₁NO₈S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 339.3620

Ref: IN-DA00IJX6

Topiramate

CAS: 97240-79-4

Topiramate

Formula: C₁₂H₂₁NO₈S

Purezza: ≥95%

Peso molecolare: 339.36

Ref: 54-BUP14122

Topiramate

CAS: 97240-79-4

Formula: C₁₂H₂₁NO₈S

Purezza: 98.0 - 102.0 % (anhydrous basis)

Colore e forma: White to almost white powder

Peso molecolare: 339.36

Ref: 7W-GC1245

Topiramate

CAS: 97240-79-4

Topiramate

Formula: C₁₂H₂₁NO₈S

Purezza: >99%

Peso molecolare: 339.36

Ref: 54-OR1028318

Topiramate

CAS: 97240-79-4

Formula: C₁₂H₂₁NO₈S

Colore e forma: White To Off-White Solid

Peso molecolare: 339.36

Ref: 4Z-T-0511

Topiramate-d12 (di-iso-propylidene-d12)

CAS: 1279037-95-4, 97240-79-4

Purezza: 99 atom % D

Colore e forma: White Solid

Peso molecolare: 351.43

Ref: 3U-D6906

Topiramate

Prodotto controllato

CAS: 97240-79-4

Formula: C₁₂H₂₁NO₈S

Colore e forma: Neat

Peso molecolare: 339.36

Ref: 86-MM1348.00

Topiramate 1.0 mg/ml in Acetonitrile

CAS: 97240-79-4

Colore e forma: Single Solution

Ref: 61-AMP1348.00-11

Topiramate, 1mg/ml in Acetonitrile

CAS: 97240-79-4

Colore e forma: Single Solution

Ref: LP-TPR-1391-1LA

Topiramate (Standard)

CAS: 97240-79-4

Topiramate (Standard) is a reference standard for research and analysis in studies involving Topiramate. Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepatic injury and largely when used in combination with other anticonvulsant medications.

Formula: C₁₂H₂₁NO₈S

Colore e forma: Solid

Peso molecolare: 339.36

Ref: TM-TMSM-3478

Topiramate

CAS: 97240-79-4

Colore e forma: Neat

Ref: 61-FOR1348.00

Topiramate

CAS: 97240-79-4

Colore e forma: Neat

Ref: LP-TPR-1391

Topiramate-13C6

Prodotto controllato

CAS: 97240-79-4

Applications Topiramate-13C6 is the labeled compound of Topiramate (T540250). Topiramate is used as an anticonvulsant.
References Maryanoff, B.E., et al.: J. Med. Chem., 30, 880 (1987); Bialer, M.: Clin. Pharmacokinet., 24(6), 441-52 (1993)

Formula: C₆C₆H₂₁NO₈S

Colore e forma: Neat

Peso molecolare: 345.318

Ref: TR-T540251

Topiramate

CAS: 97240-79-4

Applications Used as an anticonvulsant.
References Maryanoff, B.E., et al.: J. Med. Chem., 30, 880 (1987); Bialer, M.: Clin. Pharmacokinet., 24(6), 441-52 (1993)

Formula: C₁₂H₂₁NO₈S

Colore e forma: Neat

Peso molecolare: 339.36

Ref: TR-T540250