CAS 998-06-1

1,2-Dilinoleoil-sn-glicero-3-fosfocolina

Descrizione:

1,2-Dilinoleoil-sn-glicero-3-fosfocolina, comunemente noto come DLPC, è un fosfolipide che gioca un ruolo significativo nelle membrane cellulari e nelle doppie membrane lipidiche. È caratterizzato dalle sue due catene di acidi grassi linoleoyl, che contribuiscono alla sua fluidità e flessibilità, rendendolo un componente importante nella dinamica delle membrane. La molecola presenta uno scheletro di glicerolo, un gruppo fosfato e un gruppo testa di colina, che conferisce proprietà anfifiliche, permettendole di interagire con ambienti sia idrofili che idrofobici. Il DLPC è spesso utilizzato in studi biofisici e sistemi di somministrazione di farmaci grazie alla sua capacità di formare liposomi e micelle. Le sue proprietà strutturali gli consentono di stabilizzare le strutture di membrana e facilitare l'incorporazione di altre molecole, come farmaci o proteine, migliorando la loro biodisponibilità. Inoltre, il DLPC è utilizzato in varie applicazioni di ricerca, inclusi studi sulla permeabilità delle membrane e sul comportamento delle doppie membrane lipidiche in diverse condizioni. In generale, le sue caratteristiche uniche lo rendono una sostanza preziosa sia in contesti biologici che farmaceutici.

Formula: C₄₄H₈₀NO₈P

InChI: InChI=1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h14-17,20-23,42H,6-13,18-19,24-41H2,1-5H3/b16-14-,17-15-,22-20-,23-21-/t42-/m1/s1

InChI key: InChIKey=FVXDQWZBHIXIEJ-LNDKUQBDSA-N

SMILES: [C@H](OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCC/C=C\C/C=C\CCCCC)=O

Sinonimi:

• (1,2-Dilinoleoyl)-3-lecithin
• (2R)-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
• (R-(All-Z))-(4-oxido-10-oxo-7-((1-oxooctadeca-9,12-dienyl)oxy)-3,5,9-trioxa-4-phosphaheptacosa-18,21-dienyl)trimethylammonium 4-oxide
• 1,2-Dilinoleoyl-sn-3-glycerophosphorylcholine
• 1,2-Dilinoleoyl-sn-glycero-3-phosphatidylcholine
• 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine
• 1,2-Dilinoleoyl-sn-glycerol-3-phosphocholine
• 1,2-Dilinoleoylphosphocholine
• 1-Linoleoyl-2-linoleoyl-sn-glycero-3-phosphorylcholine
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxo-9,12-octadecadienyl)oxy]-, hydroxide, inner salt, 4-oxide, [R-(all-Z)]-
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxo-9,12-octadecadienyl)oxy]-, inner salt, 4-oxide, [R-(all-Z)]-
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]oxy]-, inner salt, 4-oxide, (7R,18Z,21Z)-
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[(9Z,12Z)-1-oxo-9,12-octadecadienyl]oxy]-, inner salt, 4-oxide, (7R,18Z,21Z)-
• 49: PN: WO2017201317 SEQID: 122 claimed RNA
• <span class="text-smallcaps">L</span>-(+)-α-(α′,β-Dilinoleoyl)-glycerylphosphorylcholine
• <span class="text-smallcaps">L</span>-Dilinoleoyllecithin
• <span class="text-smallcaps">L</span>-α-Dilinoleoyl phosphatidylcholine
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dilinolein, <span class="text-smallcaps">L</span>-(+)-
• DLiPC
• Linolein, 1,2-di-, dihydrogen phosphate, monoester with choline hydroxide, inner salt, <span class="text-smallcaps">L</span>-(+)-
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dilinolein, L-(+)-

1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

CAS: 998-06-1

Formula: C₄₄H₈₀NO₈P

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 782.0817

Ref: IN-DA003W1P

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

CAS: 998-06-1

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

Formula: C₄₄H₈₀NO₈P

Colore e forma: Solid-Powder

Peso molecolare: 782.08166

Ref: 54-BIL6001

1,2-Dilinoleoyl-sn-Glycero-3-Phosphatidylcholine

CAS: 998-06-1

Formula: C44H80NO8P

Purezza: >98%

Colore e forma: Solid

Peso molecolare: 782.082

Ref: 48-37-1802

L-Dilinoleoyl Lecithin

CAS: 998-06-1

Formula: C₄₄H₈₀NO₈P

Peso molecolare: 782.10

Ref: 4Z-C-59100

(R)-2,3-Bis((9Z,12Z)-octadeca-9,12-dienoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

CAS: 998-06-1

Purezza: ≥98%

Peso molecolare: 782.0969849

Ref: 10-F791285

L-Dilinoleoyllecithin

Prodotto controllato

CAS: 998-06-1

Formula: C₄₄H₈₀NO₈P

Colore e forma: Neat

Peso molecolare: 782.082

Ref: TR-D561175

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

CAS: 998-06-1

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine (DLPC) is a phospholipid that is used in the treatment of insulin resistance and inflammation. DLPC is a stable molecule that exhibits intermolecular hydrogen bonding and has been shown to be effective against inflammatory diseases. DLPC has been used as a liposomal formulation for the treatment of type 2 diabetes by improving insulin sensitivity, which may be due to its ability to inhibit proinflammatory cytokines such as tumor necrosis factor alpha (TNFα). It also binds to the receptor α, which are G protein coupled receptors present on cells involved in inflammatory responses. The binding of DLPC to these receptors leads to increased insulin sensitivity by inhibiting TNFα production.

Formula: C₄₄H₈₀NO₈P

Purezza: Min. 95%

Peso molecolare: 782.08 g/mol

Ref: 3D-FD42822

L-Dilinoleoyllecithin

CAS: 998-06-1

L-Dilinoleoyllecithin is phosphatidylcholine. It is a glycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site.

Formula: C₄₄H₈₀NO₈P

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 782.08

Ref: TM-T24393