Substrati fluorogenici
Trovati 297 prodotti di "Substrati fluorogenici"
Glycyl-glycine 7-amido-4-methylcoumarin hydrochloride
CAS:Glycyl-glycine 7-amido-4-methylcoumarin hydrochloride is a synthetic peptide substrate used as a fluorogenic substrate for aminopeptidase.Formula:C14H16ClN3O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:325.75 g/mol4-Methylumbelliferyl b-D-galactopyranoside-6-sulphate sodium salt - Moscerdam™ biochemical purity
CAS:4-MU-Gal-6S (M4A) is a fluorogenic substrate of galactose-6-sulfate sulfatase (GALNS), used for the diagnosis of Mucopolysaccharidosis IV type A (MPS IV A). MPS IV, also known as Morquio syndrome, is a rare metabolic disorder in which the human body cannot process glycosaminoglycans (GAGs). MPS IV A is caused by the deficiency of the enzyme N-acetyl-galactosamine-6-sulfatase resulting in accumulation of keratan and chondroitin sulfate in tissues. M4A is used as the GALNS substrate in the anti-lysosomal enzyme antibody assay for the treatments of lysosomal storage disorders (LSDs) with enzyme replacement therapies (ERTs).Formula:C16H17NaO11SPurezza:Min. 97 Area-%Colore e forma:White PowderPeso molecolare:440.36 g/mol4-Methylumbelliferyl oleate
CAS:Methylumbelliferyl oleate is a MOSCERDAM® substrate targeting the lipase enzymeFormula:C28H40O4Purezza:Min. 90 Area-%Colore e forma:White PowderPeso molecolare:440.61 g/mol4-Methylumbelliferyl lignocerate
CAS:4-Methylumbelliferyl lignocerate is a fluorogenic substrate for lipase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl lignocerateas a substrate for measuring the lipase activity is used for X-linked adrenoleukodystrophy diagnosis and peroxisomal disorder screening.
Formula:C34H54O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:526.79 g/mol4-Methylumbelliferyl b-D-glucosaminide - Moscerdam™ biochemical purity
CAS:A substrate used for the diagnosis of Sanfilippo disease C (MPS III C).
Formula:C16H19NO7Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:337.32 g/mol4-Methylumbelliferyl-2-O-(α-L-fucopyranosyl)-β-L-fucopyranoside
4-Methylumbelliferyl-2-O-(alpha-L-fucopyranosyl)-beta-L-fucopyranoside is a fluorogenic substrate for alpha-L-fucosidase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl-2-O-(alpha-L-fucopyranosyl)-beta-L-fucopyranosideas a substrate for measuring the alpha-L-fucosidase activity is used for diagnosis of fucosidosis (defficiency of L-fucosidase).
Purezza:Min. 95%Colore e forma:White/Off-White SolidPeso molecolare:468.45 g/mol4-Methylumbelliferyl phosphate bis(cyclohexylammonium) salt
CAS:Sensitive fluorogenic substrate for fluorometric and UV-spectrophotometric assays of phosphatases. This may also be used for in-gel assaysFormula:C22H35N2O6PPurezza:Min 99%Colore e forma:White to off-white solid.Peso molecolare:454.50 g/molMonofluoresceinated mannitol
Monofluoresceinated mannitol is a fluorescently labeled form of mannitol. It is used as a tracer for metabolism studies.Formula:C27H24O12Purezza:Min. 95%Colore e forma:PowderPeso molecolare:540.46 g/molAc-Abu-Tle-Leu-Gln-AMC TFA salt
A fluorogenic substrate for detection of enzymatic activity of the SARS-CoV-2 Mpro protease. The fluorophore 7-Amino-4-methylcoumarin (AMC) is linked to the tetrapeptide via a peptide bond at the C-terminal of the glutamine residue. Following the hydrolytic activity of the Mpro protease, the fluorogenic AMC group get released from the substrate, generating a fluorescent signal (Ex 380 nm / Em 455 nm).
Formula:C33H48N6O8(freebase)Purezza:Min. 95.0 Area-%Peso molecolare:656.77 g/molL-Lysyl-L-alanine 7-amido-4-methylcoumarin dihydrochloride
CAS:L-Lysyl-L-alanine 7-amido-4-methylcoumarin dihydrochloride is a fluorogenic peptide substrate for aminopeptidase. This AMC peptide substrate is normally used to rapidly profile the N-terminal specificity of proteases.
Purezza:Min. 98.0 Area-%Colore e forma:Powder4-Methylumbelliferyl β-D-lactoside
CAS:Fluorogenic substrate for beta-galactosidaseFormula:C22H28O13Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:500.45 g/molL-Alanine-7-amido-4-methylcoumarin hydrochloride
CAS:L-Alanine-7-amido-4-methylcoumarin hydrochloride is a synthetic peptide substrate used as a fluorogenic substrate for alanine aminopeptidase.Formula:C13H14N2O3·HClPurezza:Min. 90%Colore e forma:PowderPeso molecolare:282.72 g/mol4-Methylumbelliferyl-2-O-(a-L-fucopyranosyl)-a-L-fucopyranoside
4-Methylumbelliferyl-2-O-(alpha-L-fucopyranosyl)-alpha-L-fucopyranoside is a fluorogenic substrate for alpha-L-fucosidase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl-2-O-(alpha-L-fucopyranosyl)-alpha-L-fucopyranosideas a substrate for measuring the alpha-L-fucosidase activity is used for fucosidosis diagnosis.
Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:468.45 g/mol4-Methylumbelliferyl 2-deoxy-2-sulfamino-b-D-glucopyranoside sodium salt
4-Methylumbelliferyl 2-deoxy-2-sulfamino-beta-D-glucopyranoside sodium salt is a fluorogenic substrate for N-sulfoglucosamine sulfohydrolase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl 2-deoxy-2-sulfamino-beta-D-glucopyranoside sodium saltas a substrate for measuring the N-sulfoglucosamine sulfohydrolase activity is used for screening of Mucopolysaccharidosis IIIA (MPS IIIA) and diagnosis of Sanfilippo A syndrome.Formula:C16H19NO10SNaPurezza:Min. 95%Colore e forma:PowderPeso molecolare:439.37 g/mol4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-glucopyranoside-6-sulfate potassium
CAS:4-Methylumbelliferyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside-6-sulfate potassium is a fluorogenic substrate for N-acetylglucosamine-6-sulfatase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside-6-sulfate potassiumas a substrate for measuring the N-acetylglucosamine-6-sulfatase activity is used for screening of Mucopolysaccharidosis IIID (MPS IIID) (a rare lysosomal storage disorder) and Sanfilippo D syndrome diagnosis.Formula:C18H20KNO11SPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:497.52 g/mol5-Dodecanoylaminofluorescein di-b-D-galactopyranoside
CAS:5-Dodecanoylaminofluorescein di-b-D-galactopyranoside, commonly known as C12FDG, is a fluorogenic substrate for β-galactosidase. Fluorescein is released upon enzymatic cleavage by β-galactosidase. The intensity of its fluorescence is utilised to quantify β-galactosidase activity. C12FDG has been shown to be useful in identifying senescent cells that are associated with aging and cancer. It has also been used as a model system in some studies for studying disease activity, intracellular targets, and biological sample storage. It is also used to identify cancer tissues and radiation damage in the form of senescent cells. The chemical structure of 5DAFG is similar to that of the natural sugar galactose. 5DAFG binds to the plasma membrane of cells due to its lipophilic properties and then enters the cell through transport proteins on the cell surface called ATP binding cassette transporters.Formula:C44H55NO16Purezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:853.9 g/molFluorescein di-beta-D-galactopyranoside
CAS:Fluorogenic substrate for beta-galactosidase
Formula:C32H32O15Purezza:Min. 98 Area-%Colore e forma:Slightly Yellow PowderPeso molecolare:656.59 g/mol4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside-6-sulfate sodium salt
CAS:4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt is a high-quality fluorogenic substrate specifically designed for the detection and quantification of various enzymes, including beta-glucosidases and sulfatases. Upon hydrolysis by the target enzyme, this substrate releases the highly fluorescent 4-methylumbelliferone, allowing for real-time monitoring and accurate measurement of enzyme activities in biochemical assays, diagnostic tests, and research applications. 4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt has excellent solubility in water, ensuring a consistent and reliable performance in different experimental conditions. This versatile substrate is an essential tool for researchers and industry professionals who require a sensitive and reproducible detection method for enzymes of interest.Formula:C18H20NO11SNaPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:481.41 g/molAcetyl-L-alanine 7-amido-4-methylcoumarin
CAS:Acetyl-L-alanine 7-amido-4-methylcoumarin is a fluorogenic substrate for aminopeptidase. The enzyme cleaves the N-terminal amino acids, yielding a blue fluorescent solution.
Formula:C15H16N2O4Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:288.3 g/mol4-Methylumbelliferyl b-D-glucuronide trihydrate
CAS:Fluorogenic substrate for beta-glucuronidase GUS
Formula:C16H22O12Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:406.34 g/mol
