Substrati fluorogenici
Trovati 297 prodotti di "Substrati fluorogenici"
Resorufin-7-O-phosphate
CAS:Resorufin-7-O-phosphate is a fluorogenic substrate for alkaline phosphatase that exhibits a red color after cleavage that can be measured at ~ 585nm.
Formula:C12H6NO6P·2H4NPurezza:Min. 95%Peso molecolare:327.23 g/molRhodamine 110 chloride
CAS:Fluorescent dye substrate for flow cytometric measurements
Formula:C20H15O3N2ClPurezza:Min. 95 Area-%Colore e forma:Red PowderPeso molecolare:366.8 g/mol4-Methylumbelliferyl propionate
CAS:4-Methylumbelliferyl propionate is a fluorogenic substrate for esterase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl propionateas a substrate for measuring the esterase activity is used for esterase deficiency screening assays.
Formula:C13H12O4Purezza:Min. 95 Area-%Colore e forma:PowderPeso molecolare:232.23 g/molResorufin N-acetyl-b-D-glucosamine
CAS:Resorufin N-acetyl-b-D-glucosamine is fluorogenic substrate for N-acetyl-beta-D-glucosaminidase (NAG).
Formula:C20H20N2O8Purezza:Min. 98 Area-%Colore e forma:Orange PowderPeso molecolare:416.38 g/mol4-Methylumbelliferyl 6-thio-palmitate-b-D-glucopyranoside - Moscerdam™ biochemical purity
CAS:4-Methylumbelliferyl 6-thio-palmitate-b-D-glucopyranoside (Mu-6S-Palm-β-Glc) is a fluorogenic substrate of palmitoyl-protein thioesterase 1 (PPT1), used in the diagnosis of infantile neuronal ceroid lipofuscinosis (INCL). INCL, also known as infantile CLN1 disease, is a rapidly progressing lysosomal storage disorder (LSD), caused by a deficiency of PPT1. Mu-6S-Palm-β-Glc is also used as the substrate in the PPT assay to investigate the retention of lysosomal enzyme activity of bi-functional IgG-PPT1 fusion protein in the delivery across blood-brain barrier.
Formula:C32H48O8SPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:592.78 g/molL-Leucine 7-amido-4-methylcoumarin hydrochloride salt
CAS:L-Leucine 7-amido-4-methylcoumarin hydrochloride salt is a synthetic peptide substrate used as a fluorogenic substrate for leucine aminopeptidase.Formula:C16H21ClN2O3Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:324.8 g/mol4-Methylumbelliferyl caprylate
CAS:Used for identification of Salmonella spp. by detection of caprylate esteraseFormula:C18H22O4Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:302.36 g/molEthyl umbelliferone-3-carboxylate-α-D-glucopyranoside
Ethyl umbelliferone-3-carboxylate-a-D-glucopyranoside is a fluorogenic substrate used for detecting alpha-glucosidase activity in enzymatic assays. When alpha-glucosidase cleaves , the glycosidic bond, umbelliferone-3-carboxylate is released, which exhibits strong fluorescence. This substrate is commonly utilized in glycobiology research, diagnostic tests, and high-throughput screening of enzyme inhibitors.
Formula:C18H20O10Purezza:Min. 95%Colore e forma:Off-white to yellow solid.Peso molecolare:396.35 g/mol4-Methylumbelliferyl 2-deoxy-2-sulfamino-b-D-glucopyranoside sodium salt
4-Methylumbelliferyl 2-deoxy-2-sulfamino-beta-D-glucopyranoside sodium salt is a fluorogenic substrate for N-sulfoglucosamine sulfohydrolase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl 2-deoxy-2-sulfamino-beta-D-glucopyranoside sodium saltas a substrate for measuring the N-sulfoglucosamine sulfohydrolase activity is used for screening of Mucopolysaccharidosis IIIA (MPS IIIA) and diagnosis of Sanfilippo A syndrome.Formula:C16H19NO10SNaPurezza:Min. 95%Colore e forma:PowderPeso molecolare:439.37 g/mol4-Methylumbelliferyl-β-L-fucopyranoside
CAS:4-Methylumbelliferyl-beta-L-fucopyranoside is a fluorogenic substrate that is used in food testing. It also has uses as a chromogenic substrate and a ligand for biological studies. 4-Methylumbelliferyl-beta-L-fucopyranoside is a conjugate of 4-methylumbelliferone and beta-D-fucopyranosyl ester, which is an enzyme substrate for the detection of phosphatases. This product can be used to detect the activity of phosphatase enzymes in various media, including culture media, environmental testing, and staining. 4MUFBPY also has chemiluminescent properties that can be used for bioluminescence assays.Formula:C16H18O7Peso molecolare:322.31 g/molRef: 3D-M-5541
1gPrezzo su richiesta5gPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta2500mgPrezzo su richiesta-Unit-ggPrezzo su richiesta4-Methylumbelliferyl 2-acetamido-2-deoxy-a-D-glucopyranoside
CAS:4-Methylumbelliferyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside is a fluorogenic substrate for alpha-N-acetylglucosaminidase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl 2-acetamido-2-deoxy-alpha-D-glucopyranosideas a substrate for measuring the alpha-N-acetylglucosaminidase activity is used for Sanfilippo syndrome B screening and mucopolysaccharidosis diagnosis.Formula:C18H21NO8Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:379.36 g/mol4-Methylumbelliferyl-N-acetyl-β-D-glucosaminide-6-sulfate, sodium salt
CAS:4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt is a high-quality fluorogenic substrate specifically designed for the detection and quantification of various enzymes, including beta-glucosidases and sulfatases. Upon hydrolysis by the target enzyme, this substrate releases the highly fluorescent 4-methylumbelliferone, allowing for real-time monitoring and accurate measurement of enzyme activities in biochemical assays, diagnostic tests, and research applications. 4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt has excellent solubility in water, ensuring a consistent and reliable performance in different experimental conditions. This versatile substrate is an essential tool for researchers and industry professionals who require a sensitive and reproducible detection method for enzymes of interest.Formula:C18H20NNaO11SPurezza:Min. 98.0 Area-%Peso molecolare:481.41 g/molRef: 3D-M-5505
5mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta-Unit-ggPrezzo su richiesta5-Dodecanoylaminofluorescein di-b-D-galactopyranoside
CAS:5-Dodecanoylaminofluorescein di-b-D-galactopyranoside, commonly known as C12FDG, is a fluorogenic substrate for β-galactosidase. Fluorescein is released upon enzymatic cleavage by β-galactosidase. The intensity of its fluorescence is utilised to quantify β-galactosidase activity. C12FDG has been shown to be useful in identifying senescent cells that are associated with aging and cancer. It has also been used as a model system in some studies for studying disease activity, intracellular targets, and biological sample storage. It is also used to identify cancer tissues and radiation damage in the form of senescent cells. The chemical structure of 5DAFG is similar to that of the natural sugar galactose. 5DAFG binds to the plasma membrane of cells due to its lipophilic properties and then enters the cell through transport proteins on the cell surface called ATP binding cassette transporters.Formula:C44H55NO16Purezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:853.9 g/molFLsharp™ - Phosphate, disodium salt
FLsharp™ - Phosphate, disodium salt is a fluorogenic water-soluble substrate for phosphatase enzymes. Its chemical name is 6-Chloro-2-[5-chloro-2-(phosphonooxy)phenyl]-4(1H)-quinazolinone disodium salt and was developed by Molecular Probes in the 1990s. After cleavage of the substrate by phosphatase activity, an insoluble product is formed that is highly fluorescent in the solid state. Upon UV irradiation this very stable fluorophore emits green light in the 530 nm range for an extended period of time. FLsharp™ is a unique substrate - optimized for the detection of phosphatase activity in solid matrices such as agar media, tissue sections or microscopic preparations. FLsharp™ - Phosphate, disodium salt is used in microbiology as a substrate for bacterial phosphatases.
Purezza:Min. 95%Fluorescein di-beta-D-galactopyranoside
CAS:Fluorogenic substrate for beta-galactosidase
Formula:C32H32O15Purezza:Min. 98 Area-%Colore e forma:Slightly Yellow PowderPeso molecolare:656.59 g/molFluorescein mono-b-D-galactopyranoside
CAS:Fluorescein mono-b-D-galactopyranoside or FMG is a fluorogenic substrate for beta-galactosidase. The fluorophore fluorescein is released after enzymatic cleavage, exhibiting a greenish fluorescent. This substrate is particularly valuable in gene expression studies (e.g., lacZ reporter assays) and as a probe for cell-based assays for real-time monitoring.Purezza:Min. 95%Colore e forma:PowderPeso molecolare:494.45 g/molFluorescein diacetate
CAS:Fluorogenic substrate targeting esterases , hGSTP1-1
Formula:C24H16O7Colore e forma:PowderPeso molecolare:416.38 g/mol4-Methylumbelliferyl β-D-glucuronide
CAS:Fluorogenic substrate for b-glucuronidase GUSFormula:C16H16O9Purezza:Min. 95%Peso molecolare:352.29 g/molAcetyl-L-alanine 7-amido-4-methylcoumarin
CAS:Acetyl-L-alanine 7-amido-4-methylcoumarin is a fluorogenic substrate for aminopeptidase. The enzyme cleaves the N-terminal amino acids, yielding a blue fluorescent solution.
Formula:C15H16N2O4Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:288.3 g/molγ-L-Glutamic acid 7-amido-4-methylcoumarin trifluoroacetic acid
CAS:Substrate for aminopeptidase A
Formula:C15H16N2O5•C2F3O2HPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:418.4 g/mol
