Syk
Gli inibitori della chinasi splenica (Syk) sono composti che prendono di mira Syk, una chinasi coinvolta nella segnalazione delle cellule immunitarie e nella regolazione dell'angiogenesi. Syk svolge un ruolo nelle risposte infiammatorie che possono contribuire all'angiogenesi tumorale. L'inibizione di Syk può ridurre la formazione di vasi sanguigni indotta dall'infiammazione nei tumori, rendendo questi inibitori preziosi nella terapia del cancro e nella ricerca sull'infiammazione. Presso CymitQuimica, offriamo una gamma diversificata di inibitori di Syk di alta qualità per supportare la tua ricerca in immunologia, oncologia e angiogenesi.
Trovati 37 prodotti di "Syk"
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Piceatannol
CAS:Formula:C14H12O4Purezza:>98.0%(HPLC)Colore e forma:White to Light yellow to Light red powder to crystalPeso molecolare:244.25Gusacitinib
CAS:Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).Formula:C24H28N8O2Purezza:98.06% - 99.94%Colore e forma:SolidPeso molecolare:460.53Ref: TM-T14331
1mg39,00€5mg84,00€10mg116,00€25mg178,00€50mg333,00€100mg495,00€200mg710,00€1mL*10mM (DMSO)110,00€Adrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Formula:C9H11NO3·HClPurezza:99.94%Colore e forma:SolidPeso molecolare:217.651,3-Benzodioxole, 5-(2-nitroethenyl)-
CAS:Formula:C9H7NO4Purezza:98%Colore e forma:SolidPeso molecolare:193.1562Piceatannol
CAS:Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Formula:C14H12O4Purezza:98.66% - 99.73%Colore e forma:Light Tan To Yellow PowderPeso molecolare:244.24Lanraplenib
CAS:Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.Formula:C23H25N9OPurezza:98.35%Colore e forma:SolidPeso molecolare:443.5Ref: TM-T11824LL
1mg51,00€2mg74,00€5mg99,00€10mg167,00€25mg290,00€50mg430,00€100mg633,00€1mL*10mM (DMSO)115,00€1,2-Benzenediol, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-
CAS:Formula:C14H12O4Purezza:97%Colore e forma:SolidPeso molecolare:244.2427Tyrosine Kinase Inhibitor Library
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase relatedColore e forma:Odour SolidRef: TM-L2200
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaSyk Kinase Peptide Substrate, Biotin labeled
The compound, Biotin-labeled Syk Kinase Peptide Substrate, is a peptide substrate of Syk kinase that is labeled with biotin.Formula:C76H108N18O24S1Colore e forma:SolidPeso molecolare:1689.9Cevidoplenib dimesylate
CAS:Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.
Formula:C27H35N7O9S2Purezza:98%Colore e forma:SolidPeso molecolare:665.74Syk-IN-7
Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].
Formula:C26H31N9O4Purezza:98%Colore e forma:SolidPeso molecolare:533.58Lanraplenib succinate
CAS:Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.Formula:C58H68N18O14Colore e forma:SolidPeso molecolare:1241.294MNS
CAS:Formula:C9H7NO4Purezza:>98.0%(GC)Colore e forma:Light yellow to Yellow to Green powder to crystalPeso molecolare:193.16BAY 61-3606 dihydrochloride
CAS:BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).Formula:C20H18N6O3·2HClPurezza:99.46%Colore e forma:SolidPeso molecolare:463.32Ref: TM-T6776
1mg38,00€5mg84,00€10mg116,00€25mg187,00€50mg279,00€100mg406,00€200mg565,00€1mL*10mM (DMSO)87,00€Fostamatinib
CAS:Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.
Formula:C23H26FN6O9PPurezza:93.08% - 99.38%Colore e forma:SolidPeso molecolare:580.46TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Formula:C17H22ClFN6OPurezza:99.28% - 99.82%Colore e forma:SolidPeso molecolare:380.85Flavanomarein
CAS:Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.Formula:C21H22O11Purezza:98.63% - 99.54%Colore e forma:SolidPeso molecolare:450.39PRT-060318
CAS:PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.Formula:C18H24N6OPurezza:99.98%Colore e forma:SolidPeso molecolare:340.42PRT062607 hydrochloride
CAS:PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.Formula:C19H23N9O·HClPurezza:97.7% - 99.81%Colore e forma:SolidPeso molecolare:429.91Ref: TM-T2696
1mg60,00€2mg86,00€5mg127,00€10mg187,00€25mg326,00€50mg500,00€200mg948,00€1mL*10mM (DMSO)139,00€BAY 61-3606
CAS:BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting
Formula:C20H18N6O3Purezza:98.72%Colore e forma:SolidPeso molecolare:390.4Cerdulatinib
CAS:Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Formula:C20H27N7O3SPurezza:98.74% - 99.49%Colore e forma:SolidPeso molecolare:445.54Ref: TM-T2487
1mg42,00€2mg52,00€5mg74,00€10mg101,00€25mg175,00€50mg268,00€100mg409,00€200mg573,00€500mg888,00€1mL*10mM (DMSO)81,00€MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Formula:C9H7NO4Purezza:98.53%Colore e forma:Yellow PowderPeso molecolare:193.16R112
CAS:R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Formula:C16H13FN4O2Purezza:99.27% - 99.84%Colore e forma:SolidPeso molecolare:312.3Ref: TM-T3185
1mg39,00€2mg51,00€5mg84,00€10mg124,00€25mg219,00€50mg329,00€100mg487,00€500mg1.026,00€1mL*10mM (DMSO)92,00€Fostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Formula:C23H24FN6O9P·2NaPurezza:96.13% - 99.09%Colore e forma:SolidPeso molecolare:624.42Ref: TM-T2605
1mg47,00€2mg55,00€5mg88,00€10mg124,00€25mg221,00€50mg374,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)116,00€Entospletinib
CAS:Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!Formula:C23H21N7OPurezza:98.54% - 99.74%Colore e forma:SolidPeso molecolare:411.46Ref: TM-T6101
1mg38,00€2mg49,00€5mg81,00€10mg97,00€25mg170,00€50mg259,00€100mg416,00€200mg617,00€1mL*10mM (DMSO)88,00€R406
CAS:R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.Formula:C22H23FN6O5·C6H6O3SPurezza:97.67% - 98.82%Colore e forma:SolidPeso molecolare:628.63Ref: TM-T6174
1mg46,00€2mg57,00€5mg89,00€10mg142,00€25mg299,00€50mg445,00€100mg647,00€1mL*10mM (DMSO)120,00€R406 free base
CAS:R406 free base (R406 (free base)) is a potent Syk inhibitor.Formula:C22H23FN6O5Purezza:97.64% - 99.11%Colore e forma:SolidPeso molecolare:470.45Ref: TM-T2467
1mg47,00€5mg70,00€10mg97,00€25mg187,00€50mg338,00€100mg535,00€500mg1.121,00€1mL*10mM (DMSO)72,00€Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formula:C20H28ClN7O3SPurezza:99.85%Colore e forma:SolidPeso molecolare:482Syk Inhibitor II
CAS:Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).Formula:C14H15F3N6OPurezza:97.63%Colore e forma:SolidPeso molecolare:340.3ER-27319
CAS:ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosineFormula:C20H22N2O5Purezza:98%Colore e forma:SolidPeso molecolare:370.4Sovleplenib
CAS:Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors & ITP studies.Formula:C24H30N6O3SPurezza:99.71%Colore e forma:SolidPeso molecolare:482.6Ref: TM-T32088
1mg127,00€5mg305,00€10mg459,00€25mg777,00€50mg1.216,00€100mg1.890,00€200mg2.547,00€1mL*10mM (DMSO)324,00€RO9021
CAS:RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).Formula:C18H25N7OPurezza:99.90%Colore e forma:SolidPeso molecolare:355.44Syk-IN-3
CAS:Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.
Formula:C24H28N4O3SPurezza:97.29% - >99.99%Colore e forma:SolidPeso molecolare:452.57OXSI-2
CAS:OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.Formula:C18H15N3O3SPurezza:98%Colore e forma:Dark Orange SolidPeso molecolare:353.39Lanraplenib monosuccinate
CAS:Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.Formula:C27H31N9O5Purezza:98%Colore e forma:SolidPeso molecolare:561.59MK-8457
CAS:MK-8457 is a dual inhibitor of SYK and ZAP70, valuable for rheumatoid arthritis research [1].Formula:C24H25F3N4O3SColore e forma:SolidPeso molecolare:506.54Syk-IN-8
CAS:Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells.
Formula:C23H26N10Purezza:98%Colore e forma:SolidPeso molecolare:442.52
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