Trombina
Gli inibitori della trombina sono composti che bloccano la trombina, un enzima coinvolto nel processo di coagulazione del sangue che ha anche un ruolo nella promozione dell'angiogenesi. La trombina può stimolare la formazione di nuovi vasi sanguigni nei tumori, favorendone la crescita e la metastasi. Inibendo la trombina, questi composti possono ridurre l'angiogenesi e la progressione tumorale. Gli inibitori della trombina sono importanti sia nella ricerca sul cancro che nello studio delle malattie vascolari. Presso CymitQuimica, offriamo una selezione di inibitori della trombina di alta qualità per supportare la tua ricerca in emostasi, oncologia e angiogenesi.
Trovati 52 prodotti di "Trombina"
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Dabigatran etexilate
CAS:<p>Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.</p>Formula:C34H41N7O5Purezza:98.19% - 99.98%Colore e forma:White PowderPeso molecolare:627.73Dabigatran ethyl ester hydrochloride
CAS:Dabigatran prevents blood clots, inhibiting NQO2 and thrombin with IC50 0.8 μM.Formula:C27H30ClN7O3Purezza:99.65%Colore e forma:SolidPeso molecolare:536.03Befovacimab
CAS:<p>Befovacimab, a human IgG2 antibody, targets TFPI for hemophilia A/B research.</p>Colore e forma:LiquidKnob A peptide GPRPFPAC
CAS:Knob A peptide GPRPFPAC is a fibrin knob peptide. The PEGylated form of Knob A peptide GPRPFPAC exhibits enhanced anticoagulant activity.Formula:C38H57N11O9SColore e forma:SolidPeso molecolare:843.99Hirudin (55-65) (sulfated)
CAS:Hirudin (55-65) (sulfated), a fragment of Hirudin, is a thrombin inhibitor with anticoagulant effects and blood anticoagulant properties.Formula:C64H90N12O27SColore e forma:SolidPeso molecolare:1491.53Metolazone
CAS:<p>Metolazone (SR-720-22) is a quinazoline-sulfonamide derived diuretic that inhibits sodium chloride symporters.</p>Formula:C16H16ClN3O3SPurezza:98.14% - 98.5%Colore e forma:Crystals From Ethanol SolidPeso molecolare:365.83Thrombin (MW 37kDa)
CAS:Thrombin (MW 37kDa) is a trypsin-like allosteric serine protease.Purezza:98%Colore e forma:SolidPeso molecolare:37kDaIchorcumab
CAS:<p>Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.</p>Colore e forma:LiquidProtease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Colore e forma:Odour SolidHirudin (54-65) (TFA)
Hirudin (54-65) TFA, a segment of the 65-amino-acid protein Hirudin, exhibits anticoagulant properties [1].Colore e forma:Odour SolidSulodexide
CAS:Sulodexide is an orally administered combination of glycosaminoglycans, consisting of low molecular weight heparin (80%) and dermatan sulfate (20%). It demonstrates antithrombotic properties by interacting with antithrombin III (AT III) and heparin cofactor II (HC II), and by inhibiting thrombin formation. Additionally, sulodexide enhances profibrinolytic activity by releasing tissue plasminogen activator (tPA). It also offers endothelial protection, possesses anti-inflammatory effects, and alleviates chronic venous disease.Colore e forma:SolidPlatelet aggregation-IN-1
<p>Platelet aggregation-IN-1 (Compound 10e) acts as an inhibitor of platelet aggregation and can achieve complete (100%) inhibition of thrombin-induced platelet aggregation at a concentration of 50 μM.</p>Formula:C18H13N3O4Peso molecolare:335.09061Thrombin inhibitor 13
Thrombin inhibitor 13 (Compound 13a) acts as a covalent reversible inhibitor of thrombin (thrombin, FIIa) with an IC50 of 0.7 nM. This compound prolongs activated partial thromboplastin time (aPTT) and prothrombin time (PT), demonstrating both antithrombotic and anticoagulant properties.Formula:C16H17ClN6OSColore e forma:SolidPeso molecolare:376.864Fibrinopeptide B, human
CAS:Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.Formula:C66H93N19O25Purezza:98%Colore e forma:SolidPeso molecolare:1552.56Fibrinogen-Binding Peptide
CAS:Fibrinogen-binding peptide mimics vitronectin site and activates platelets; thrombin turns it to fibrin.Formula:C25H39N7O8Purezza:98%Colore e forma:SolidPeso molecolare:565.62H-Gly-Arg-pNA dihydrochloride
CAS:H-Gly-Arg-pNA 2HCl, a peptide, binds 1,2 thrombin; colorimetric quantification at 405 nm indicates thrombin activity.Formula:C14H23Cl2N7O4Purezza:99.14%Colore e forma:SolidPeso molecolare:424.28PM 102
CAS:<p>Peptide that reverses the anticoagulant effect of heparin. Potently binds heparin (Kd = 36 nM in vitro).</p>Formula:C235H425N111O64Purezza:98%Colore e forma:SolidPeso molecolare:5830Acetyl-Hirudin (54-65) (sulfated)
CAS:Acetyl-Hirudin (54-65) (sulfated) binds thrombin-rHCII(L444R), blocking rHCII's N-terminal/thrombin exosite I interaction, stabilizing the complex.Formula:C68H95N13O29SColore e forma:SolidPeso molecolare:1590.63Anti-Coagulation Factor II Antibody (8M286)
Anti-Coagulation Factor II Antibody (8M286) is a Rabbit antibody targeting Coagulation Factor II. Anti-Coagulation Factor II Antibody (8M286) can be used in ELISA.Colore e forma:Odour LiquidAnti-Coagulation Factor II Antibody (2P591)
<p>Anti-Coagulation Factor II Antibody (2P591) is a Rabbit antibody targeting Coagulation Factor II. Anti-Coagulation Factor II Antibody (2P591) can be used in WB.</p>Colore e forma:Odour Liquid
