Chinasi di serina/treonina
Gli inibitori delle chinasi serina/treonina sono composti che prendono di mira gli enzimi responsabili della fosforilazione dei residui di serina e treonina sulle proteine, i quali svolgono un ruolo cruciale nella regolazione dell'apoptosi e di altri processi cellulari. Queste chinasi sono coinvolte in vie di segnalazione che controllano la crescita, la divisione e la morte cellulare programmata. Inibire specifiche chinasi serina/treonina può alterare l'equilibrio tra sopravvivenza cellulare e apoptosi, rendendo questi inibitori strumenti essenziali nella ricerca sul cancro e in altre aree della biologia cellulare. Presso CymitQuimica, offriamo una selezione completa di inibitori delle chinasi serina/treonina di alta qualità per supportare la tua ricerca in apoptosi, trasduzione del segnale e meccanismi delle malattie.
Trovati 18 prodotti di "Chinasi di serina/treonina"
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CRA-2059
CAS:CRA-2059 is a selective and reversible inhibitor of human tryptase beta, exhibiting a Ki value of 620 pM against recombinant human tryptase beta (rHTβ).Formula:C34H46N12O8Purezza:97.68%Colore e forma:SolidPeso molecolare:750.82BMT-124110 Formate
<p>BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase</p>Formula:C22H20N2O2Purezza:99.52%Colore e forma:SoildPeso molecolare:344.41TLK1-IN-1
TLK1-IN-1 (Compound 5n) is a TLK1 inhibitor with an IC50 of 7.2 μM for TLK1B and a GI50 of 2.7 μM for LNCaP cells. It induces DNA damage and apoptosis (Apoptosis) in cancer cells and is applicable in prostate cancer research.Formula:C24H23BrClN5O3Peso molecolare:544.83PKD-IN-1
CAS:CRT0066101 is an inhibitor of PKD.Formula:C18H19ClN4OPurezza:98%Colore e forma:SolidPeso molecolare:342.82kb NB 142-70
CAS:kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively).Formula:C11H9NO2S2Purezza:98.15% - ≥95%Colore e forma:SolidPeso molecolare:251.32SGC-GAK-1
CAS:<p>SGC-GAK-1 is a selective cyclin G-associated kinase (GAK) inhibitor (Ki: 3.1 nM).</p>Formula:C18H17BrN2O3Purezza:99.85%Colore e forma:SolidPeso molecolare:389.24CID755673
CAS:CID755673 inhibits PKD (IC50: 182 nM), with selectivity over PLK1, AKT, CAMKIIα, CAK, PKC.Formula:C12H11NO3Purezza:97.68% - 99.84%Colore e forma:SolidPeso molecolare:217.221-Naphthyl PP1
CAS:<p>1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)</p>Formula:C19H19N5Purezza:99.85%Colore e forma:White Cyrstalline SolidPeso molecolare:317.39N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine
CAS:<p>Novel 2,6-naphthyridine inhibits PKC/PKD, identified by HTS.</p>Formula:C23H28N6Purezza:98.35%Colore e forma:SolidPeso molecolare:388.51CID 2011756
CAS:<p>CID 2011756 is an ATP-competitive and specific PKD1 inhibitor.</p>Formula:C22H21ClN2O3Purezza:98.15% - ≥95%Colore e forma:SolidPeso molecolare:396.87Benzamidine hydrochloride
CAS:<p>Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin.</p>Formula:C7H9ClN2Purezza:99.25% - 99.97%Colore e forma:White To Off-White PowderPeso molecolare:156.61SPHINX31
CAS:<p>SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).</p>Formula:C27H24F3N5O2Purezza:98.81% - 99.3%Colore e forma:SolidPeso molecolare:507.51GAK inhibitor 49
CAS:GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ).Formula:C20H22N2O5Purezza:98.71%Colore e forma:SolidPeso molecolare:370.4Anti-Mouse CD11b Antibody (M1/70)
The Anti-Mouse CD11b Antibody is a rat-derived IgG2b monoclonal antibody that targets the CD11b antigen on mouse cells.Colore e forma:Odour LiquidSRPKIN-1
CAS:SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).Formula:C27H21FN2O3SPurezza:98%Colore e forma:SolidPeso molecolare:472.53MS-444
CAS:<p>MS-444 (BE-34776) is an MLCK and HuR inhibitor with antitumor activity that can be used to study triple-negative breast cancer and colorectal cancer.</p>Formula:C13H10O4Purezza:99.45% - 99.45%Colore e forma:SolidPeso molecolare:230.22Protein kinase inhibitor 14
CAS:Protein kinase inhibitor 14 (Compound 13) exhibits inhibitory effects on various serine/threonine kinases and receptor/non-receptor tyrosine kinases.Formula:C22H22F2N6OPeso molecolare:424.447Anti-neuroinflammation agent 3
CAS:Compound A.10.3 (Anti-neuroinflammation agent 3) exhibits inhibitory activity against various Ser/Thr kinases or receptor/non-receptor tyrosine kinases.Formula:C22H23FN6O2Peso molecolare:422.455
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