
TNF
Gli inibitori del fattore di necrosi tumorale (TNF) sono composti che bloccano l'attività del TNF, una citochina coinvolta nell'infiammazione e nella regolazione dell'apoptosi. Il TNF può indurre l'apoptosi in alcuni tipi di cellule mentre promuove la sopravvivenza e l'infiammazione in altri. L'inibizione del TNF è cruciale nel trattamento delle malattie autoimmuni, delle condizioni infiammatorie croniche e di alcuni tipi di cancro. Gli inibitori del TNF aiutano a modulare la risposta immunitaria e a ridurre i danni ai tessuti causati da un'infiammazione eccessiva. Presso CymitQuimica, offriamo una vasta gamma di inibitori del TNF di alta qualità per supportare la tua ricerca in immunologia, infiammazione e apoptosi.
Trovati 58 prodotti di "TNF"
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Utomilumab
CAS:Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.Formula:C17H24N8O3Purezza:95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:142.77 kDaUCB-9260
CAS:UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.Formula:C26H25N5OPurezza:98.39% - 99.24%Colore e forma:SolidPeso molecolare:423.51Ref: TM-T13951
1mg97,00€2mgPrezzo su richiesta5mg230,00€10mg373,00€25mg635,00€50mg847,00€100mg1.169,00€200mgPrezzo su richiesta1mL*10mM (DMSO)259,00€Certolizumab pegol
CAS:Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.Purezza:96.7% (SDS-PAGE); 96.5% (SEC-HPLC) - 98.2% (SDS-PAGE); 99.1% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:47.74 kDaConatumumab
CAS:Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Purezza:> 95% - > 95%Colore e forma:LiquidPeso molecolare:145.44 kDa(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.Formula:C27H39N5O7Purezza:97.61% - 99.72%Colore e forma:SolidPeso molecolare:545.63Varlilumab
CAS:Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.Purezza:SDS-PAGE:95% SEC-HPLC:98.65%Colore e forma:LiquidPeso molecolare:146 kDaMK-4166
MK-4166 is a humanized IgG1 agonistic monoclonal antibody targeting GITR. It is capable of enhancing the proliferation of both naive T lymphocytes and tumor-infiltrating T lymphocytes.Dapirolizumab
Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.Purezza:>95%Colore e forma:LiquidPeso molecolare:150 kDaRO7567132
RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.Colore e forma:Odour LiquidRagifilimab
CAS:Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.
Purezza:SDS-PAGE:95% SEC-HPLC:99.99%Colore e forma:LiquidPeso molecolare:146.46 kDaTNF-α Antagonist
CAS:TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction withFormula:C58H71N11O15S2Colore e forma:SolidPeso molecolare:1226.39TNF-α (46-65), human
CAS:Human TNF alpha (46-65) peptide.Formula:C110H172N24O30Purezza:98%Colore e forma:SolidPeso molecolare:2310.69DSTYSLSSTLTLSK TFA
DSTYSLSSTLTLSK TFA detects infliximab, a chimeric IgG1 antibody targeting TNF-α.Formula:C66H108F3N15O28Colore e forma:SolidPeso molecolare:1616.64Pamlectabart
Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.Purezza:95%Colore e forma:LiquidPeso molecolare:145.20 kDaPlaculumab
CAS:Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.Colore e forma:LiquidSotigalimab
CAS:Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.Purezza:98.50% - 98.50%Colore e forma:LiquidTengonermin
CAS:Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.Colore e forma:LiquidTNF-α-IN-9
CAS:TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.Formula:C17H14O4Purezza:99.21%Colore e forma:SoildPeso molecolare:282.29Acetyl tetrapeptide-2
CAS:Acetyl tetrapeptide-2 is a skin conditioner, by soothing and nourishing the skin through similar mechanisms as other peptides.Formula:C26H39N5O9Purezza:98%Colore e forma:SolidPeso molecolare:565.62KGYY15
CAS:KGYY15 (Mouse KGYY15), a peptide that targets CD40, exhibits weak inhibition of the CD40-CD40L interaction, with an IC50 exceeding 1 mM. At a concentration of 100 μM, KGYY15 activates the NF-κB pathway by 33%.Formula:C84H129N21O22SColore e forma:SolidPeso molecolare:1817.12

