TNF
Gli inibitori del fattore di necrosi tumorale (TNF) sono composti che bloccano l'attività del TNF, una citochina coinvolta nell'infiammazione e nella regolazione dell'apoptosi. Il TNF può indurre l'apoptosi in alcuni tipi di cellule mentre promuove la sopravvivenza e l'infiammazione in altri. L'inibizione del TNF è cruciale nel trattamento delle malattie autoimmuni, delle condizioni infiammatorie croniche e di alcuni tipi di cancro. Gli inibitori del TNF aiutano a modulare la risposta immunitaria e a ridurre i danni ai tessuti causati da un'infiammazione eccessiva. Presso CymitQuimica, offriamo una vasta gamma di inibitori del TNF di alta qualità per supportare la tua ricerca in immunologia, infiammazione e apoptosi.
Trovati 94 prodotti di "TNF"
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Conatumumab
CAS:Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Purezza:> 95% - > 95%Colore e forma:LiquidPeso molecolare:145.44 kDaUCB-9260
CAS:UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.Formula:C26H25N5OPurezza:98.39% - 99.24%Colore e forma:SolidPeso molecolare:423.51Ref: TM-T13951
1mg92,00€2mg133,00€5mg219,00€1mL*10mM (DMSO)245,00€10mg353,00€25mg602,00€50mg802,00€100mg1.108,00€200mg1.485,00€Ruplizumab
CAS:PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.Purezza:98.5% (SDS-PAGE); 98.7% (SEC-HPLC) - 98.5% (SDS-PAGE); 98.7% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:145.42 kDa(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.Formula:C27H39N5O7Purezza:97.61% - 99.72%Colore e forma:SolidPeso molecolare:545.63Iscalimab
CAS:Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.Purezza:>95%Colore e forma:LiquidPeso molecolare:146.08 kDaCertolizumab pegol
CAS:Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.Purezza:96.7% (SDS-PAGE); 96.5% (SEC-HPLC) - 98.2% (SDS-PAGE); 99.1% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:47.74 kDaOzoralizumab
CAS:Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Purezza:SDS-PAGE:> 95%;SEC-HPLC:95.6%Colore e forma:LiquidPeso molecolare:38.44 kDaLucatumumab
CAS:Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.Purezza:95.5% (SDS-PAGE); 98.4% (SEC-HPLC) - 95.5% (SDS-PAGE); 98.4% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:146.15 kDaEnavatuzumab
CAS:Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.Purezza:>95%Colore e forma:LiquidPeso molecolare:150 kDaTeneliximab
CAS:Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.Purezza:99.19% (SEC-HPLC) - >95.0% (SDS-PAGE)Colore e forma:LiquidPeso molecolare:146.06 kDaUtomilumab
CAS:Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.Formula:C17H24N8O3Purezza:95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:142.77 kDaPamlectabart
Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.Purezza:95%Colore e forma:LiquidPeso molecolare:145.20 kDaLenercept
CAS:Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].Colore e forma:LiquidTengonermin
CAS:Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.Colore e forma:LiquidDSTYSLSSTLTLSK TFA
DSTYSLSSTLTLSK TFA detects infliximab, a chimeric IgG1 antibody targeting TNF-α.Formula:C66H108F3N15O28Colore e forma:SolidPeso molecolare:1616.64Varlilumab
CAS:Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.Purezza:SDS-PAGE:95% SEC-HPLC:98.65%Colore e forma:LiquidPeso molecolare:146 kDaPegsunercept
CAS:Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].Colore e forma:LiquidEfaprinermin alfa
CAS:Efaprimermin alfa (OMP-336B11) is a human monoclonal antibody that targets TNFRSF18, and functions as a GITR ligand-Fc fusion protein [1].Colore e forma:LiquidRO7567132
RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.Colore e forma:Odour LiquidTNF-α Antagonist
CAS:TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction withFormula:C58H71N11O15S2Colore e forma:SolidPeso molecolare:1226.39
