Survivin
Gli inibitori della survivina prendono di mira la proteina survivina, un membro della famiglia degli inibitori dell'apoptosi (IAP) che è altamente espressa nelle cellule tumorali e le aiuta a sfuggire all'apoptosi. La survivina svolge un ruolo chiave nella regolazione del ciclo cellulare e nell'inibizione dell'apoptosi, rendendola un bersaglio critico nella terapia del cancro. Inibendo la survivina, questi composti possono promuovere l'apoptosi nelle cellule tumorali, offrendo potenziali benefici terapeutici. Presso CymitQuimica, offriamo una selezione di inibitori della survivina di alta qualità per supportare la tua ricerca in oncologia, apoptosi e sviluppo terapeutico.
Trovati 14 prodotti di "Survivin"
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MNK8
CAS:MNK8 is a potent STAT3 inhibitor, impairs DNA binding, and inhibits liver cancer cell growth.Formula:C15H12N2O2Purezza:99.74%Colore e forma:SolidPeso molecolare:252.27ZLDI-8
CAS:<p>ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein.</p>Formula:C24H23N3O3SPurezza:98.09%Colore e forma:SolidPeso molecolare:433.52MX106-4C
<p>MX106-4C is a survivin inhibitor that selectively targets ABCB1-positive colorectal cancer cells. It can work synergistically with Doxorubicin for enhanced anticancer effects or restore Doxorubicin sensitivity in drug-resistant ABCB1 cells.</p>Formula:C23H25BrN2O2Peso molecolare:440.10994HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Colore e forma:Lyophilized PowderPeso molecolare:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result.NSC 80467
CAS:NSC 80467 inhibits survivin, targets DNA synthesis, induces γH2AX, and pKAP1 markers of DNA damage.Formula:C24H22BrN3O5Purezza:99.25%Colore e forma:SolidPeso molecolare:512.35HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Colore e forma:Lyophilized PowderPeso molecolare:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 55-63 kDa based on Tris-Bis PAGE result.HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Colore e forma:Lyophilized PowderPeso molecolare:The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.LQZ-7I
CAS:LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumorsFormula:C20H14F2N4Purezza:99.81% - 99.87%Colore e forma:SolidPeso molecolare:348.35Cucurbitacin IIA
CAS:1.Formula:C32H50O8Purezza:98.62% - 99.87%Colore e forma:SolidPeso molecolare:562.73Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formula:C15H16O3Purezza:98.76%Colore e forma:SolidPeso molecolare:244.291-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS:<p>SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.</p>Formula:C21H13ClF3N3O2Purezza:99.41%Colore e forma:SolidPeso molecolare:431.8Sepantronium bromide
CAS:<p>Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.</p>Formula:C20H19BrN4O3Purezza:99.68% - 99.85%Colore e forma:SolidPeso molecolare:443.26GDP366
CAS:<p>GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.</p>Formula:C20H17N5OSPurezza:98.78% - 99.84%Colore e forma:SolidPeso molecolare:375.45AQIM-I
CAS:<p>AQIM-I is a survivin inhibitor that reduces survivin expression and colony formation. It promotes reactive oxygen species (ROS) production, apoptosis, cell cycle arrest, DNA damage, and autophagy. Moreover, AQIM-I effectively inhibits nonsmall cell lung cancer cells A549, with an IC 50 value of 9 nM [1].</p>Formula:C17H13IN2O2Colore e forma:SolidPeso molecolare:404.20
