Integrina
Gli inibitori delle integrine prendono di mira le integrine, una famiglia di recettori di superficie cellulare che svolgono un ruolo cruciale nell'adesione cellulare, nella migrazione e nella trasduzione del segnale. Le integrine sono coinvolte nella regolazione del ciclo cellulare, in particolare in processi come la divisione e la differenziazione cellulare. L'inibizione delle integrine può interrompere questi processi, portando all'arresto del ciclo cellulare e all'apoptosi, rendendo questi inibitori strumenti preziosi nella ricerca sul cancro e nello studio delle metastasi. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle integrine di alta qualità per supportare la tua ricerca sulla regolazione del ciclo cellulare, la biologia del cancro e lo sviluppo terapeutico.
Trovati 239 prodotti di "Integrina"
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ATN-161 acetate
CAS:ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.Formula:C25H39N9O10SPurezza:98.27%Colore e forma:SoildPeso molecolare:657.7Ref: TM-T10398L
1mg190,00€5mg471,00€10mg663,00€25mg1.036,00€50mg1.429,00€100mg1.830,00€200mg2.498,00€Cibisatamab
CAS:Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Purezza:SDS-PAGE:99.1%;SEC-HPLC:96.5%Colore e forma:LiquidPeso molecolare:191.1 kDaArg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.Formula:C17H31N7O10Purezza:98.14%Colore e forma:SolidPeso molecolare:493.47Abciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Purezza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Colore e forma:LiquidPeso molecolare:95.18 kDaElarofiban TFA
CAS:Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.Formula:C26H34F6N4O8Purezza:99.08%Colore e forma:SoildPeso molecolare:644.56Orbofiban TFA
CAS:Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFormula:C19H24F3N5O6Purezza:97.21% - 98.72%Colore e forma:SolidPeso molecolare:475.42Otelixizumab
CAS:Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.Purezza:>95%Colore e forma:LiquidRWJ 50271
CAS:RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Formula:C18H17F3N4O2SPurezza:99.09%Colore e forma:SolidPeso molecolare:410.41Ref: TM-T12783
1mg127,00€5mg311,00€10mg472,00€25mg747,00€50mg1.017,00€100mg1.311,00€200mg1.786,00€1mL*10mM (DMSO)344,00€Tadocizumab
CAS:Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.Purezza:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:47.59 kDaEfalizumab
CAS:Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.Purezza:SDS-PAGE:95% SEC-HPLC:98.77%Colore e forma:LiquidPeso molecolare:146.14 kDaBersanlimab
CAS:Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Purezza:> 95% - > 95%Colore e forma:LiquidPeso molecolare:144.22 kDaVedolizumab
CAS:Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.Purezza:SDS-PAGE:98.4%;SEC-HPLC:99.1%Colore e forma:LiquidPeso molecolare:146.80 kDaAbrilumab
CAS:Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Purezza:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Colore e forma:LiquidATN-161 trifluoroacetate salt
CAS:ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formula:C25H36F3N9O10SPurezza:98% - 99.98%Colore e forma:SolidPeso molecolare:711.67Teplizumab
CAS:Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.Purezza:SDS-PAGE:95.8%;SEC-HPLC:99.7%Colore e forma:LiquidPeso molecolare:145.79 kDaMumefural
CAS:Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.
Formula:C12H12O9Colore e forma:SolidPeso molecolare:300.22LDV FITC
CAS:fluorescent ligand that binds to the α4β1 integrin (VLA-4)Formula:C69H81N11O17SPurezza:98%Colore e forma:SolidPeso molecolare:1368.53Anti-EMMPRIN/CD147 Antibody
Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.Colore e forma:Odour LiquidAB-3PRGD2
CAS:AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.
Formula:C137H215IN30O45SColore e forma:SolidPeso molecolare:3161.32SMS 121
CAS:SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.Formula:C20H21NO5Purezza:98.29%Colore e forma:SoildPeso molecolare:355.38
