Integrina
Gli inibitori delle integrine prendono di mira le integrine, una famiglia di recettori di superficie cellulare che svolgono un ruolo cruciale nell'adesione cellulare, nella migrazione e nella trasduzione del segnale. Le integrine sono coinvolte nella regolazione del ciclo cellulare, in particolare in processi come la divisione e la differenziazione cellulare. L'inibizione delle integrine può interrompere questi processi, portando all'arresto del ciclo cellulare e all'apoptosi, rendendo questi inibitori strumenti preziosi nella ricerca sul cancro e nello studio delle metastasi. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle integrine di alta qualità per supportare la tua ricerca sulla regolazione del ciclo cellulare, la biologia del cancro e lo sviluppo terapeutico.
Trovati 276 prodotti di "Integrina"
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Abrilumab
CAS:Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Purezza:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:143.80 kDaOrbofiban TFA
CAS:Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFormula:C19H24F3N5O6Purezza:97.21% - 98.72%Colore e forma:SolidPeso molecolare:475.42RWJ 50271
CAS:RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Formula:C18H17F3N4O2SPurezza:99.09%Colore e forma:SolidPeso molecolare:410.41Ref: TM-T12783
1mg120,00€5mg295,00€1mL*10mM (DMSO)326,00€10mg447,00€25mg707,00€50mg964,00€100mg1.243,00€200mg1.693,00€Foralumab
CAS:Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.Purezza:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:146.59 kDaEfalizumab
CAS:Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.Purezza:SDS-PAGE:95% SEC-HPLC:98.77%Colore e forma:LiquidPeso molecolare:146.14 kDaArg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.Formula:C17H31N7O10Purezza:98.14%Colore e forma:SolidPeso molecolare:493.47Otelixizumab
CAS:Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.Purezza:>95%Colore e forma:LiquidPeso molecolare:144.58 kDaATN-161 trifluoroacetate salt
CAS:ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formula:C25H36F3N9O10SPurezza:98% - 99.98%Colore e forma:SolidPeso molecolare:711.67ATN-161 acetate
CAS:ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.Formula:C25H39N9O10SPurezza:98.27%Colore e forma:SoildPeso molecolare:657.7Ref: TM-T10398L
1mg190,00€5mg471,00€10mg663,00€25mg1.036,00€50mg1.429,00€100mg1.830,00€200mg2.498,00€Abituzumab
CAS:Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.Purezza:>95%Colore e forma:LiquidPeso molecolare:144.58 kDaTadocizumab
CAS:Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.Purezza:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:47.59 kDaVedolizumab
CAS:Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.Purezza:SDS-PAGE:98.4%;SEC-HPLC:99.1%Colore e forma:LiquidPeso molecolare:146.80 kDaBersanlimab
CAS:Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Purezza:> 95% - > 95%Colore e forma:LiquidPeso molecolare:144.22 kDaElarofiban TFA
CAS:Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.Formula:C26H34F6N4O8Purezza:99.08%Colore e forma:SoildPeso molecolare:644.56Teplizumab
CAS:Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.Purezza:SDS-PAGE:95.8%;SEC-HPLC:99.7%Colore e forma:LiquidPeso molecolare:145.79 kDaCibisatamab
CAS:Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Purezza:SDS-PAGE:99.1%;SEC-HPLC:96.5%Colore e forma:LiquidPeso molecolare:191.1 kDaAbciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Purezza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Colore e forma:LiquidPeso molecolare:95.18 kDaGantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Formula:C21H29N5O6Purezza:99.57%Colore e forma:SolidPeso molecolare:447.48LDV FITC
CAS:fluorescent ligand that binds to the α4β1 integrin (VLA-4)Formula:C69H81N11O17SPurezza:98%Colore e forma:SolidPeso molecolare:1368.53Fibronectin CS1 Peptide
CAS:Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.Formula:C38H64N8O15Purezza:98%Colore e forma:SolidPeso molecolare:872.96
