CymitQuimica logo
Integrina

Integrina

Gli inibitori delle integrine prendono di mira le integrine, una famiglia di recettori di superficie cellulare che svolgono un ruolo cruciale nell'adesione cellulare, nella migrazione e nella trasduzione del segnale. Le integrine sono coinvolte nella regolazione del ciclo cellulare, in particolare in processi come la divisione e la differenziazione cellulare. L'inibizione delle integrine può interrompere questi processi, portando all'arresto del ciclo cellulare e all'apoptosi, rendendo questi inibitori strumenti preziosi nella ricerca sul cancro e nello studio delle metastasi. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle integrine di alta qualità per supportare la tua ricerca sulla regolazione del ciclo cellulare, la biologia del cancro e lo sviluppo terapeutico.

Trovati 256 prodotti di "Integrina"

Ordinare per

Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
prodotti per pagina.
  • Surovatamig


    Surovatamig is a bispecific antibody of the (H-γ4_L-κ)_VH-G4(h-CH2-CH3) type, targeting CD3D/CD3E/CD19.
  • MORF-627

    CAS:
    MORF-627 is an orally active selective inhibitor of integrin αvβ6 (integrinαvβ6), with an IC50 of 9.2 nM as measured in a human serum ligand binding assay. It effectively inhibits αvβ6-mediated activation of TGF-β1 with an IC50 of 2.63 nM and suppresses SMAD2/3 phosphorylation, showing an IC50 of 8.3 nM. Additionally, MORF-627 ameliorates bleomycin-induced pulmonary fibrosis in mice.
    Formula:C31H40FN3O4
    Peso molecolare:537.67
  • αvβ6-IN-1


    αvβ6-IN-1 (compound 28) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 8.1. This compound shows potential for research in idiopathic pulmonary fibrosis.
    Formula:C25H32F2N4O3
    Colore e forma:Solid
    Peso molecolare:474.54
  • αvβ6-IN-2


    <p>αvβ6-IN-2 (compound 20) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 7.8. It shows potential for use in research on idiopathic pulmonary fibrosis.</p>
    Formula:C25H30F3N3O3
    Colore e forma:Solid
    Peso molecolare:477.52
  • c(avb6)-DOTA TFA


    c(avb6)-DOTA TFA is a conjugate formed by the coupling of a selective αvβ6 integrin cyclic peptide and a DPTA chelating agent. The Lu (III) complex of c(avb6)-DOTA TFA exhibits considerable affinity for αvβ6 integrin (IC50=0.8 nM), making it suitable for tumor diagnostics.
    Formula:C69H102F3N17O20
    Colore e forma:Solid
    Peso molecolare:1546.65
  • Indatuximab


    <p>Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.</p>
    Purezza:>95%
    Colore e forma:Liquid
    Peso molecolare:145.5 kDa
  • GRGDSPK

    CAS:
    <p>GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.</p>
    Formula:C28H49N11O11
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:715.76
  • C16Y

    CAS:
    C16Y, a short peptide, serves as an inhibitor for the integrins αvβ3 and α5β1. It targets the cell membrane and exerts its antitumor activity by inhibiting angiogenesis.
    Formula:C78H115N17O17
    Colore e forma:Solid
    Peso molecolare:1562.85
  • GSK 3008348 hydrochloride

    CAS:
    GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.
    Formula:C29H37N5O2xHCl
    Purezza:99.54%
    Colore e forma:Solid
    Peso molecolare:0
  • Azelaoyl PAF

    CAS:
    Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones.promotes the uptake of oxLDL by macrophages by upregulating CD36 expression.
    Formula:C33H66NO9P
    Colore e forma:Solid
    Peso molecolare:651.85
  • Obtustatin triacetate


    <p>Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of the</p>
    Formula:C184H284N52O57S8·3C2H4O2
    Purezza:99.51%
    Colore e forma:Solid
    Peso molecolare:4573.21
  • BT100


    <p>BT100, an aptamer, impedes the interaction of von Willebrand factor (VWF) with platelet glycoprotein GPIb, thus obstructing arterial thrombosis [1].</p>
    Purezza:98%
    Colore e forma:Odour Solid
  • Volociximab

    CAS:
    <p>Volociximab (M200) is an IgG4 monoclonal antibody targeting the α5β1 integrin , with antiangiogenic, antitumor and anticancer activity, inhibits the growth of rabbit VX2 tumors and is used to study solid tumors.</p>
    Purezza:95%
    Colore e forma:Liquid
  • GPRP

    CAS:
    GPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor.
    Formula:C18H31N7O5
    Colore e forma:White To Off-White Powder
    Peso molecolare:425.48
  • RGD Trifluoroacetate

    CAS:
    RGD Trifluoroacetate is a tripeptide for cell adhesion, effective on 24 integrins, and widely used for synthetic surface binding.
    Formula:C14H23F3N6O8
    Purezza:98%
    Colore e forma:Soild
    Peso molecolare:460.36
  • Anti-Mouse CD3 Antibody (17A2)


    Anti-Mouse CD3 Antibody (17A2) is an IgG2b class antibody of murine origin targeting CD3 and can be used to study TCR signaling and antigen recognition.
    Colore e forma:Odour Liquid
  • Lifitegrast sodium

    CAS:
    <p>Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.</p>
    Formula:C29H23Cl2N2NaO7S
    Purezza:99.33%
    Colore e forma:Solid
    Peso molecolare:637.46
  • MK-0429

    CAS:
    MK-0429 is an orally active, selective, and nonpeptide antagonist of αvβ3 integrin (IC50: 80 nM).
    Formula:C23H29N5O4
    Colore e forma:Solid
    Peso molecolare:439.51
  • Cilengitide TFA

    CAS:
    Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.
    Formula:C29H41F3N8O9
    Colore e forma:Solid
    Peso molecolare:702.68
  • Arg-Gly-Asp TFA (99896-85-2(free base))


    Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.
    Formula:C14H23F3N6O8
    Purezza:99.2% - ≥98%
    Colore e forma:Solid
    Peso molecolare:460.36
  • Arginine-glycine-aspartic acid

    CAS:
    RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.
    Formula:C12H22N6O6
    Purezza:99.11%
    Colore e forma:Solid
    Peso molecolare:346.34
  • Cyclo(RADfK)

    CAS:
    Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.
    Formula:C28H43N9O7
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:617.7
  • Leukadherin-1

    CAS:
    Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.
    Formula:C22H15NO4S2
    Purezza:98.49% - 98.93%
    Colore e forma:Solid
    Peso molecolare:421.49
  • OSU-T315

    CAS:
    <p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>
    Formula:C30H30F3N5O
    Purezza:98.69%
    Colore e forma:Solid
    Peso molecolare:533.59
  • iRGD peptide

    CAS:
    <p>iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.</p>
    Formula:C35H57N13O14S2
    Purezza:98.77%
    Colore e forma:Solid
    Peso molecolare:948.04
  • H-Gly-Arg-Gly-Asp-Asn-Pro-OH

    CAS:
    RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.
    Formula:C23H38N10O10
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:614.61
  • Pyrintegrin

    CAS:
    <p>Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.</p>
    Formula:C23H25N5O3S
    Purezza:99.19%
    Colore e forma:Solid
    Peso molecolare:451.54
  • PND-1186

    CAS:
    PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).
    Formula:C25H26F3N5O3
    Purezza:99.14% - 99.75%
    Colore e forma:Solid
    Peso molecolare:501.5
  • Orbofiban

    CAS:
    Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.
    Formula:C17H23N5O4
    Colore e forma:Solid
    Peso molecolare:361.4
  • Cyclo(RGDyK) trifluoroacetate

    CAS:
    <p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>
    Formula:C31H43F6N9O12
    Purezza:95.28% - ≥95%
    Colore e forma:Solid
    Peso molecolare:847.72
  • TR-14035

    CAS:
    TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).
    Formula:C24H21Cl2NO5
    Purezza:98.98%
    Colore e forma:Solid
    Peso molecolare:474.33
  • Cyclo(-RGDfK)

    CAS:
    Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.
    Formula:C27H41N9O7
    Purezza:95.29% - >99.99%
    Colore e forma:Solid
    Peso molecolare:603.67
  • Carotegrast methyl HCl

    CAS:
    Carotegrast methyl (AJM300/PTC-100) is an oral α4 integrin blocker reducing inflammation and experimental colitis.
    Formula:C25H20Cl3N3O5
    Colore e forma:Solid
    Peso molecolare:548.801
  • Lifitegrast

    CAS:
    <p>Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.</p>
    Formula:C29H24Cl2N2O7S
    Purezza:99.39% - 99.66%
    Colore e forma:Solid
    Peso molecolare:615.48
  • ILK-IN-3

    CAS:
    ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.
    Formula:C10H12N6O
    Purezza:99.69%
    Colore e forma:Solid
    Peso molecolare:232.24
  • GLPG0187

    CAS:
    GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).
    Formula:C29H37N7O5S
    Purezza:99.4% - 99.70%
    Colore e forma:Solid
    Peso molecolare:595.71
  • Eptifibatide acetate (148031-34-9 free base)

    CAS:
    Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.
    Formula:C35H49N11O9S2·xC2H4O2
    Purezza:99.7% - 99.87%
    Colore e forma:Solid
    Peso molecolare:831.96 (free base)
  • Natalizumab

    CAS:
    Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.
    Purezza:97.15% (SDS-PAGE); 97.2% (SEC-HPLC) - 98.00%
    Colore e forma:Liquid
    Peso molecolare:N/A
  • Irigenin

    CAS:
    Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra
    Formula:C18H16O8
    Purezza:99.50% - 99.85%
    Colore e forma:Solid
    Peso molecolare:360.31
  • Carotegrast methyl

    CAS:
    Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.
    Formula:C28H26Cl2N4O5
    Purezza:99.26% - 99.72%
    Colore e forma:Solid
    Peso molecolare:569.44
  • Cilengitide

    CAS:
    Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.
    Formula:C27H40N8O7
    Purezza:98% - 99.8%
    Colore e forma:Solid
    Peso molecolare:588.66
  • Cucurbitacin B

    CAS:
    Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.
    Formula:C32H46O8
    Purezza:97.1% - 99.33%
    Colore e forma:Solid
    Peso molecolare:558.70
  • Cyclo(-RGDfK) TFA

    CAS:
    Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).
    Formula:C29H42F3N9O9
    Purezza:98.99% - 99.54%
    Colore e forma:Solid
    Peso molecolare:717.69
  • BIO-1211

    CAS:
    BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).
    Formula:C36H48N6O9
    Purezza:99.33%
    Colore e forma:Solid
    Peso molecolare:708.8
  • roxifiban

    CAS:
    <p>Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.</p>
    Formula:C21H29N5O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:447.48
  • CWHM-12

    CAS:
    <p>CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).</p>
    Formula:C26H32BrN5O6
    Purezza:98.05% - 99.83%
    Colore e forma:Solid
    Peso molecolare:590.47
  • E7820

    CAS:
    <p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>
    Formula:C17H12N4O2S
    Purezza:98.31% - 99.11%
    Colore e forma:Solid
    Peso molecolare:336.37
  • A-286982

    CAS:
    <p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>
    Formula:C24H27N3O4S
    Purezza:97.81%
    Colore e forma:Solid
    Peso molecolare:453.55
  • A-205804

    CAS:
    A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.
    Formula:C15H12N2OS2
    Purezza:98.07% - 98.52%
    Colore e forma:Solid
    Peso molecolare:300.4
  • MNS

    CAS:
    MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
    Formula:C9H7NO4
    Purezza:98.53%
    Colore e forma:Yellow Powder
    Peso molecolare:193.16
  • Tirofiban hydrochloride monohydrate

    CAS:
    <p>Tirofiban(MK383) hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>
    Formula:C22H39ClN2O6S
    Purezza:98.81% - >99.99%
    Colore e forma:White Solid
    Peso molecolare:495.07
  • ILK-IN-2

    CAS:
    <p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>
    Formula:C30H30F3N5O
    Purezza:99.30%
    Colore e forma:Solid
    Peso molecolare:533.59
  • LXW7

    CAS:
    <p>LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (</p>
    Formula:C29H48N12O12S2
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:820.89
  • GPRP acetate (67869-62-9 free base)

    CAS:
    <p>GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.</p>
    Formula:C20H35N7O7
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:485.53
  • Etaracizumab

    CAS:
    <p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>
    Purezza:96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)
    Colore e forma:Liquid
    Peso molecolare:144.3 (kDa)
  • RO0270608

    CAS:
    RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.
    Formula:C24H19Cl3N2O4
    Purezza:98.26%
    Colore e forma:Solid
    Peso molecolare:505.78
  • Bexotegrast

    CAS:
    Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).
    Formula:C27H36N6O3
    Purezza:99.53%
    Colore e forma:Solid
    Peso molecolare:492.61
  • Muromonab

    CAS:
    <p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>
    Purezza:95% - 97.51% (SEC-HPLC)
    Colore e forma:Liquid
  • Vonsetamig

    CAS:
    Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.
    Colore e forma:Liquid
  • Linvoseltamab

    CAS:
    Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/
    Colore e forma:Liquid
  • Vibecotamab

    CAS:
    Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.
    Colore e forma:Liquid
  • Obrindatamab

    CAS:
    Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.
    Colore e forma:Liquid
  • Anti-Mouse TCR γ/δ Antibody (UC7-13D5)


    Anti-Mouse TCR gamma/delta Antibody is a host Armenian Hamster-derived IgG class inhibitor targeting the mouse TCR gamma/delta receptor.
    Colore e forma:Odour Liquid
  • Voxalatamab

    CAS:
    Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].
    Colore e forma:Liquid
  • Pacanalotamab

    CAS:
    Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.
    Colore e forma:Liquid
  • Alnuctamab

    CAS:
    Alnuctamab (EM901) is a humanized, asymmetric two-arm IgG T-cell engager (TCE) with potential applications in immunological research [1].
    Colore e forma:Liquid
  • Anti-Mouse IL-1a Antibody (ALF-161)


    Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.
    Purezza:98%
    Colore e forma:Odour Liquid
  • Vatelizumab

    CAS:
    Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.
    Purezza:95%
    Colore e forma:Liquid
  • OS-2966


    OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.
    Purezza:95%
    Colore e forma:Odour Liquid
  • Caplacizumab

    CAS:
    Caplacizumab (ALX-0681), a humanized anti-von Willebrand factor (vWF) nanobody, serves to impede vWF-mediated platelet adhesion, thereby averting additional
    Colore e forma:Liquid
  • Anti-Mouse CD3ε Antibody (145-2C11)


    Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activation
    Purezza:99%
    Colore e forma:Odour Liquid
  • Gresonitamab

    CAS:
    Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.
    Colore e forma:Liquid
  • Rovelizumab

    CAS:
    Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.
    Purezza:95% - 95%
    Colore e forma:Liquid
  • Vepsitamab

    CAS:
    Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.
    Colore e forma:Liquid
  • Cevostamab

    CAS:
    <p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>
    Colore e forma:Liquid
  • Pavurutamab

    CAS:
    Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.
    Colore e forma:Liquid
  • Enlimomab

    CAS:
    <p>Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.</p>
    Colore e forma:Liquid
  • Pasotuxizumab

    CAS:
    <p>Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA &amp; CD3 with K D s 47.0 &amp; 9.4 nM, for mCRPC research.</p>
    Colore e forma:Liquid
  • Ubamatamab

    CAS:
    <p>Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].</p>
    Colore e forma:Liquid
  • Tepoditamab

    CAS:
    <p>Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.</p>
    Colore e forma:Liquid
  • Flotetuzumab

    CAS:
    Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.
    Colore e forma:Liquid
  • SB273005

    CAS:
    SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
    Formula:C22H24F3N3O4
    Purezza:99.58%
    Colore e forma:Solid
    Peso molecolare:451.44
  • Tirofiban

    CAS:
    Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
    Formula:C22H36N2O5S
    Purezza:99.83%
    Colore e forma:Solid
    Peso molecolare:440.6
  • Integrin modulator 1

    CAS:
    Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.
    Formula:C13H14N2O4
    Purezza:99.61%
    Colore e forma:Solid
    Peso molecolare:262.26
  • RUC-1

    CAS:
    RUC-1 is an αIIbβ3-selective ADP-induced platelet aggregation inhibitor.
    Formula:C11H15N5OS
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:265.33
  • Valategrast

    CAS:
    Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.
    Formula:C30H32Cl3N3O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:604.95
  • Integrin-IN-2

    CAS:
    Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.
    Formula:C27H30N4O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:458.55
  • IS-741 potassium

    CAS:
    IS-741 potassium is a phospholipase A2 inhibitor.
    Formula:C15H19F3KN3O3S
    Colore e forma:Solid
    Peso molecolare:417.49
  • IS-741 calcium

    CAS:
    IS-741 calcium is a phospholipase A2 inhibitor.
    Formula:C30H38CaF6N6O6S2
    Colore e forma:Solid
    Peso molecolare:796.86
  • UR-2922

    CAS:
    UR-2922: Oral GPIIb/IIIa blocker with <1 nM affinity, slow 90 min k(off), no LIBS or prothrombotic effects.
    Formula:C25H25N7O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:519.51
  • Zaurategrast ethyl ester sulfate

    CAS:
    Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.
    Formula:C56H60Br2N8O10S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1197.01
  • Chrysotobibenzyl

    CAS:
    Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.
    Formula:C19H24O5
    Colore e forma:Solid
    Peso molecolare:332.39
  • Zaurategrast ethyl ester

    CAS:
    Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.
    Formula:C28H29BrN4O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:549.46
  • IMB-10

    CAS:
    IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.
    Formula:C19H15NOS2
    Colore e forma:Solid
    Peso molecolare:337.46
  • XVA143

    CAS:
    XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.
    Formula:C25H21Cl2N3O8
    Colore e forma:Solid
    Peso molecolare:562.36
  • MK-0668 Mesylate

    CAS:
    MK-0668 Mesylate is the mesylate form of MK-0668 that is a very potent and orally active very late antigen-4 antagonist.
    Formula:C32H34Cl2N6O9S2
    Colore e forma:Solid
    Peso molecolare:781.68
  • MK-0668

    CAS:
    <p>MK-0668 is a very potent and orally active very late antigen-4 antagonist.</p>
    Formula:C31H30Cl2N6O6S
    Colore e forma:Solid
    Peso molecolare:685.58
  • Nexinhib20

    CAS:
    Nexinhib20 is an inhibitor of exosome synthesis and transport with anti-inflammatory activity, inhibits RAB27A and neutral sphingomyelinase 2 (nSMase2) nsMase2.
    Formula:C15H16N4O3
    Purezza:99.89%
    Colore e forma:Solid
    Peso molecolare:300.31
  • GR 144053 trihydrochloride

    CAS:
    platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist
    Formula:C18H30Cl3N5O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:454.82
  • Zalunfiban

    CAS:
    RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.
    Formula:C16H18N8O2S
    Colore e forma:Solid
    Peso molecolare:386.43