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CDK

CDK

Gli inibitori delle chinasi ciclina-dipendenti (CDK) sono composti che bloccano l'attività delle CDK, un gruppo di chinasi proteiche che regolano il ciclo cellulare, la trascrizione e altri processi cellulari. Le CDK vengono attivate legandosi alle cicline e la loro attività è cruciale per la progressione delle cellule attraverso le diverse fasi del ciclo cellulare. Inibire le CDK può bloccare la divisione cellulare, portando all'arresto del ciclo cellulare e all'apoptosi, in particolare nelle cellule tumorali in cui le CDK sono spesso disregolate. Gli inibitori delle CDK sono ampiamente utilizzati nella ricerca sul cancro e hanno un potenziale terapeutico nel trattamento di vari tipi di cancro. Presso CymitQuimica, offriamo una selezione completa di inibitori delle CDK di alta qualità per supportare la tua ricerca sul controllo del ciclo cellulare, sul cancro e sullo sviluppo terapeutico.

Trovati 522 prodotti di "CDK"

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  • LDC4297
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    LDC4297

    CAS:
    LDC4297 (LDC044297) is a potent and selective CDK7 inhibitor.
    Formula:C23H28N8O
    Purezza:98.25%
    Colore e forma:Solid
    Peso molecolare:432.52

    Ref: TM-T4051

  • CDK5-IN-3
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    CDK5-IN-3

    CAS:
    CDK5-IN-3 is a selective and potent CDK5 inhibitor that inhibits CDK5/p25 and CDK2/CycA, and can be used in the study of cancer.
    Formula:C22H26N4O
    Purezza:98.21%
    Colore e forma:Solid
    Peso molecolare:362.47

    Ref: TM-T61362

  • Palbociclib-d8
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    Palbociclib-d8

    CAS:
    Palbociclib-d8 (PD 0332991 D8) is the deuterated form of Palbociclib. Palbociclib is a CDK inhibitor that inhibits CDK4 and CDK6.
    Formula:C24H21D8N7O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:455.58

    Ref: TM-T12355

  • NCT02
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    NCT02

    CAS:
    NCT02 degrades cyclin K, leading to CCNK and CDK12 degradation, potentially aiding metastatic CRC research.
    Formula:C17H16N2O2S
    Colore e forma:Solid
    Peso molecolare:312.39

    Ref: TM-T60030

  • NU6102
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    NU6102

    CAS:
    NU6102 is a CDK2 inhibitor with antitumor activity against CDK1/cyclinB, CDK1/CDK2, CDK4, DYRK1A , PDK1, and ROCKII, and it can be used to study rectal cancer.
    Formula:C18H22N6O3S
    Purezza:99.76%
    Colore e forma:Solid
    Peso molecolare:402.47

    Ref: TM-T28218

  • Palbociclib hydrochloride
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    Palbociclib hydrochloride

    CAS:
    Palbociclib hydrochloride is the salt form of Palbociclib, a selective and orally available CDK4 and CDK6 inhibitor for breast and hepatocellular carcinoma.
    Formula:C24H31Cl2N7O2
    Purezza:99.89%
    Colore e forma:Solid
    Peso molecolare:520.46

    Ref: TM-T63576

  • FMF-04-159-2
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    FMF-04-159-2

    CAS:
    FMF-04-159-2 is a potent covalent CDK14 & CDK2 inhibito and is able to reduce α-Syn aggregation in neurons, and inhibits TNBC cancer progression.
    Formula:C28H30Cl3N7O5S
    Purezza:96.57%
    Colore e forma:Solid
    Peso molecolare:683.01

    Ref: TM-T11309

  • SB1317
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    SB1317

    CAS:
    SB1317 (TG02) is a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3).
    Formula:C23H24N4O
    Purezza:99.86%
    Colore e forma:Solid
    Peso molecolare:372.46

    Ref: TM-T2653

  • Ribociclib-d6
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    Ribociclib-d6

    CAS:
    Ribociclib-d6 is a deuterated compound of Ribociclib (LEE011) for isotope tracing.Ribociclib is an orally available CDK4/6 inhibitor with antitumor activity.
    Formula:C23H30N8O
    Colore e forma:Solid
    Peso molecolare:440.57

    Ref: TM-TMID-0003

  • CDK9-IN-1
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    CDK9-IN-1

    CAS:
    CDK9-IN-1 is a selective and potent CDK9 inhibitor with antiviral activity used in the study of PRRSV infections.
    Formula:C26H21N5O4S
    Purezza:98.52%
    Colore e forma:Solid
    Peso molecolare:499.54

    Ref: TM-T10741

  • (E/Z)-Zotiraciclib hydrochloride
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    (E/Z)-Zotiraciclib hydrochloride

    CAS:
    (E/Z)-Zotiraciclib ((E/Z)-TG02) hydrochloride is a potent inhibitor of CDK2, JAK2, and FLT3.
    Formula:C23H25ClN4O
    Colore e forma:Solid
    Peso molecolare:408.93

    Ref: TM-T62056

  • GP-82996
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    GP-82996

    CAS:
    GP-82996 (CINK4) inhibits CDK4/6; IC50s: 1.5 μM (CDK4/D1), 5.6 μM (CDK6/D1), 25 μM (Cdk5/p35); triggers U2OS cancer cell apoptosis.
    Formula:C27H32N6O
    Purezza:99.94%
    Colore e forma:Solid
    Peso molecolare:456.58

    Ref: TM-T21720

  • Atuveciclib
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    Atuveciclib

    CAS:
    Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.
    Formula:C18H18FN5O2S
    Purezza:98.8%
    Colore e forma:Solid
    Peso molecolare:387.43

    Ref: TM-T10464L

  • DRB
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    DRB

    CAS:
    <p>DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 μM)</p>
    Formula:C12H12Cl2N2O4
    Purezza:99.46% - 99.83%
    Colore e forma:White To Off-White Crystalline Solid
    Peso molecolare:319.14

    Ref: TM-T7789

  • Cdk5 Substrate acetate
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    Cdk5 Substrate acetate

    <p>Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.</p>
    Formula:C55H103N15O14
    Purezza:96.21%
    Colore e forma:Solid
    Peso molecolare:1198.5

    Ref: TM-T37207L

  • PF-06873600
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    PF-06873600

    CAS:
    PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.
    Formula:C20H27F2N5O4S
    Purezza:98.77% - 99.55%
    Colore e forma:Solid
    Peso molecolare:471.52

    Ref: TM-T8463

  • AMG 925 HCl
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    AMG 925 HCl

    CAS:
    AMG 925 HCl is a selective and potent dual inhibitor of FLT3 (IC50: 2±1 nM) and CDK4 (IC50: 3±1 nM).
    Formula:C26H30ClN7O2
    Colore e forma:Solid
    Peso molecolare:508.02

    Ref: TM-T63487

  • CKI-7
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    CKI-7

    CAS:
    CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.
    Formula:C11H14Cl3N3O2S
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:358.67

    Ref: TM-T19913

  • Palbociclib
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    Palbociclib

    CAS:
    Palbociclib is an oral CDK4/6 inhibitor, halts Rb phosphorylation, arrests cell cycle, and curbs tumor growth.
    Formula:C24H29N7O2
    Purezza:98% - 99.9%
    Colore e forma:Solid
    Peso molecolare:447.53

    Ref: TM-T1785

  • CDK9-IN-30
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    CDK9-IN-30

    CAS:
    CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.
    Formula:C16H20FNO3
    Purezza:99.75%
    Colore e forma:Solid
    Peso molecolare:293.33

    Ref: TM-T9632