Microtubulo associato
Gli inibitori delle proteine associate ai microtubuli prendono di mira le proteine che interagiscono con i microtubuli, i componenti strutturali del citoscheletro della cellula essenziali per la divisione cellulare. Queste proteine regolano la stabilità e la dinamica dei microtubuli durante la mitosi. L'inibizione delle proteine associate ai microtubuli può interrompere la funzione dei microtubuli, portando all'arresto del ciclo cellulare e all'apoptosi, in particolare nelle cellule tumorali a rapida divisione. Questi inibitori sono ampiamente utilizzati nella ricerca sul cancro e nello sviluppo di farmaci. Presso CymitQuimica, offriamo una gamma completa di inibitori di proteine associate ai microtubuli di alta qualità per supportare la tua ricerca sulla divisione cellulare, la dinamica del citoscheletro e la terapia del cancro.
Trovati 283 prodotti di "Microtubulo associato"
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MT-7
CAS:MT-7 is a tubulin polymerization inhibitor.Formula:C22H17N3O2Purezza:98%Colore e forma:SolidPeso molecolare:355.39Tubulin inhibitor 7
CAS:Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (Formula:C21H14N2O4Purezza:98%Colore e forma:SolidPeso molecolare:358.35Alyssin, (R)-
CAS:Alyssin, (R)-, is an analogue of Sulforaphane that has been shown to have cytotoxic effect on CCRF-SB leukemia cells and lymphoblastoid cells.Formula:C7H13NOS2Colore e forma:SolidPeso molecolare:191.31Cemadotin hydrochloride
CAS:Cemadotin hydrochloride (LU103793) is a synthetic mitosis inhibitor derived from Dolastatin 15 for treating solid tumors.Formula:C35H57ClN6O5Colore e forma:SolidPeso molecolare:677.33Alyssin, (S)-
CAS:Alyssin, (S)-, is an analogue of Sulforaphane that has been shown to have cytotoxic effect on CCRF-SB leukemia cells and lymphoblastoid cells.Formula:C7H13NOS2Colore e forma:SolidPeso molecolare:191.31OX01914
CAS:OX01914 is a soluble modulator to increase utrophin in DMD studies, EC50 20.5 μM.Formula:C17H14N4OColore e forma:SolidPeso molecolare:290.32Denibulin HCl
CAS:Denibulin (MN-029) disrupts tumor blood vessels by inhibiting microtubule assembly, enhancing radiation and cisplatin efficacy.Formula:C18H20ClN5O3SColore e forma:SolidPeso molecolare:421.9Centmitor-1
CAS:Centmitor-1 is a novel mitotic inducer that modulates the positive end of microtubules and reduces microtubule dynamics.Formula:C22H16BrN3O3Colore e forma:SolidPeso molecolare:450.28CAY10701
CAS:CAY10701, a 7-deazahypoxanthine, impedes cell growth (GI50: 9-38 nM) while sparing normal fibroblasts (>1,500-fold), and shrinks mouse colorectal tumors.Formula:C24H19N3O2Colore e forma:SolidPeso molecolare:381.43CHM-1-P-Na
CAS:CHM-1-P-Na is used as a hydrophilic prodrug of CHM-1.Formula:C16H11FNNaO6PColore e forma:SolidPeso molecolare:386.227Tubulin inhibitor 28
CAS:Compound 2g, a tubulin inhibitor with an IC50 of 1.2 μM, inhibits MCF-7 cell proliferation.Formula:C12H8Br2S2Colore e forma:SolidPeso molecolare:376.13Tubulin polymerization-IN-39
Tubulin-IN-39 inhibits polymerization (IC50: 4.9 μM), blocks colchicine site, stops cancer growth.Formula:C21H21N5O5Colore e forma:SolidPeso molecolare:423.42Anticancer agent 48
CAS:Compound 48: broad-spectrum, anti-proliferative, inhibits microtubules, active in vivo, with potential for tumor research.Formula:C26H25N3O4Colore e forma:SolidPeso molecolare:443.49Microtubule inhibitor 1
CAS:Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity(IC50 = 9-16 nM, in cancer cells).Formula:C21H19NO3Purezza:98%Colore e forma:SolidPeso molecolare:333.38Microtubule inhibitor 3
CAS:Compounds 17o and 17p with furan have IC50s of 14.0 and 2.9 nM, respectively, against NCI-H460 cancer cells.Formula:C26H23FN4O3Colore e forma:SolidPeso molecolare:458.48Amphethinile
CAS:Amphethinile is an anti-tubulin agent. The Ka of Amphethinile with tubulin is 1.3 μM.Formula:C15H11N3SPurezza:98%Colore e forma:SolidPeso molecolare:265.33Sirt1/2-IN-1
CAS:Sirt1/2-IN-1 inhibits SIRT1 (IC50: 1.81 μg/mL) and SIRT2 (2.10 μg/mL), less on SIRT3 (20.5 μg/mL), with anticancer properties.Formula:C22H13ClN2OS2Colore e forma:SolidPeso molecolare:420.93Tubulozole
CAS:Tubulozole blocks mitosis by inhibiting microtubule dynamics, leading to cell cycle arrest and apoptosis.Formula:C23H23Cl2N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:508.42Mivobulin
CAS:Mivobulin is an inhibitor of tubulin .Formula:C17H19N5O2Purezza:98%Colore e forma:SolidPeso molecolare:325.37S-methyl DM1
CAS:S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.Formula:C36H50ClN3O10SPurezza:98%Colore e forma:SolidPeso molecolare:752.31
