Microtubulo associato
Gli inibitori delle proteine associate ai microtubuli prendono di mira le proteine che interagiscono con i microtubuli, i componenti strutturali del citoscheletro della cellula essenziali per la divisione cellulare. Queste proteine regolano la stabilità e la dinamica dei microtubuli durante la mitosi. L'inibizione delle proteine associate ai microtubuli può interrompere la funzione dei microtubuli, portando all'arresto del ciclo cellulare e all'apoptosi, in particolare nelle cellule tumorali a rapida divisione. Questi inibitori sono ampiamente utilizzati nella ricerca sul cancro e nello sviluppo di farmaci. Presso CymitQuimica, offriamo una gamma completa di inibitori di proteine associate ai microtubuli di alta qualità per supportare la tua ricerca sulla divisione cellulare, la dinamica del citoscheletro e la terapia del cancro.
Trovati 280 prodotti di "Microtubulo associato"
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Tubulin polymerization-IN-25
CAS:Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) & FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.Formula:C24H18N2O3SColore e forma:SolidPeso molecolare:414.48Tubulin polymerization-IN-15
CAS:Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].Formula:C18H17N3O4Colore e forma:SolidPeso molecolare:339.35Tubulin inhibitor 18
CAS:"Tubulin inhibitor 18 (5j), a potent chalcone, uniquely structured for cancer research."Formula:C22H26O5Colore e forma:SolidPeso molecolare:370.44Tubulin/MMP-IN-1
Tubulin/MMP-IN-1 inhibits tubulin, MMP, and cancer cell growth; disrupts cell cycles and induces apoptosis.Formula:C38H44NO9PColore e forma:SolidPeso molecolare:689.73Tubulin inhibitor 12
CAS:New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.Formula:C24H20N2OColore e forma:SolidPeso molecolare:352.43Tau tracer 1
CAS:Tau tracer 1 is a radiopharmaceutical for imaging Tau aggregates linked to neurodegenerative disease diagnosis.Formula:C34H23N5O2Colore e forma:SolidPeso molecolare:533.591Iso-Fludelone
CAS:Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.Formula:C27H36F3NO6Colore e forma:SolidPeso molecolare:527.57Antitumor agent-68
CAS:Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.Formula:C17H11NO2Colore e forma:SolidPeso molecolare:261.27Antitumor agent-71
CAS:Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.Formula:C26H31N5O4SColore e forma:SolidPeso molecolare:509.62IDT
CAS:IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.Formula:C8H5NS2Purezza:98%Colore e forma:SolidPeso molecolare:179.26DHNQ
CAS:DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).Formula:C18H14N2OColore e forma:SolidPeso molecolare:274.32D011-2120
CAS:D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.Formula:C17H15NO3Purezza:98%Colore e forma:SolidPeso molecolare:281.31DAT1
CAS:DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.Formula:C17H15N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:325.38Acodazole
CAS:Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.Formula:C20H19N5OPurezza:98%Colore e forma:SolidPeso molecolare:345.4Acodazole hydrochloride
CAS:Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.Formula:C20H20ClN5OPurezza:98%Colore e forma:SolidPeso molecolare:381.86LDN-193665
CAS:LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.Formula:C15H11FN4OSPurezza:98%Colore e forma:SolidPeso molecolare:314.34GF 15
CAS:GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.Formula:C23H21ClO6Purezza:98%Colore e forma:SolidPeso molecolare:428.86TOK-8801
CAS:TOK-8801 is a dihydroimidazole thiazole carboxamide with immunomodulatory activity.Formula:C17H21N3OSPurezza:99.97%Colore e forma:SolidPeso molecolare:315.43Alyssin, (R)-
CAS:Alyssin, (R)-, is an analogue of Sulforaphane that has been shown to have cytotoxic effect on CCRF-SB leukemia cells and lymphoblastoid cells.Formula:C7H13NOS2Colore e forma:SolidPeso molecolare:191.31Cemadotin hydrochloride
CAS:Cemadotin hydrochloride (LU103793) is a synthetic mitosis inhibitor derived from Dolastatin 15 for treating solid tumors.Formula:C35H57ClN6O5Colore e forma:SolidPeso molecolare:677.33
