Microtubulo associato
Gli inibitori delle proteine associate ai microtubuli prendono di mira le proteine che interagiscono con i microtubuli, i componenti strutturali del citoscheletro della cellula essenziali per la divisione cellulare. Queste proteine regolano la stabilità e la dinamica dei microtubuli durante la mitosi. L'inibizione delle proteine associate ai microtubuli può interrompere la funzione dei microtubuli, portando all'arresto del ciclo cellulare e all'apoptosi, in particolare nelle cellule tumorali a rapida divisione. Questi inibitori sono ampiamente utilizzati nella ricerca sul cancro e nello sviluppo di farmaci. Presso CymitQuimica, offriamo una gamma completa di inibitori di proteine associate ai microtubuli di alta qualità per supportare la tua ricerca sulla divisione cellulare, la dinamica del citoscheletro e la terapia del cancro.
Trovati 284 prodotti di "Microtubulo associato"
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Microtubule inhibitor 4
CAS:Microtubule inhibitor 4 (Compound 2) blocks polymerization, toxic to HT-29 cells (IC50: 2.1 nM).Formula:C25H23FN4O3Colore e forma:SolidPeso molecolare:446.47BNC105P
CAS:BNC105P, a prodrug VDA, converts to BNC105, blocks tubulin polymerization, disrupts tumor vessels, and evades P-glycoprotein resistance.Formula:C20H21O10PColore e forma:SolidPeso molecolare:452.3485Tubulin polymerization-IN-29
CAS:Tubulin polymerization-IN-29 inhibits microtubule assembly, has anti-proliferative properties, and arrests HeLa cells at G2/M.Formula:C25H20FNO6Colore e forma:SolidPeso molecolare:449.43isoCA-4
CAS:isoCA-4 is a Combretastatin A4 derivative. isoCA-4 is a tubulin polymerization inhibitor with anti-proliferative activities [1].Formula:C18H20O5Colore e forma:SolidPeso molecolare:316.35IDT
CAS:IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.Formula:C8H5NS2Purezza:98%Colore e forma:SolidPeso molecolare:179.26DHNQ
CAS:DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).Formula:C18H14N2OColore e forma:SolidPeso molecolare:274.32D011-2120
CAS:D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.Formula:C17H15NO3Purezza:98%Colore e forma:SolidPeso molecolare:281.31DAT1
CAS:DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.Formula:C17H15N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:325.38Acodazole
CAS:Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.Formula:C20H19N5OPurezza:98%Colore e forma:SolidPeso molecolare:345.4Acodazole hydrochloride
CAS:Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.Formula:C20H20ClN5OPurezza:98%Colore e forma:SolidPeso molecolare:381.86LDN-193665
CAS:LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.Formula:C15H11FN4OSPurezza:98%Colore e forma:SolidPeso molecolare:314.34MG-2119
CAS:MG-2119 is a potent inhibitor of monomeric tau and α-syn aggregation and can be used to study neurological diseases.Formula:C27H29N5O4Colore e forma:SolidPeso molecolare:487.55Aha1/Hsp90-IN-1
CAS:Aha1/Hsp90-IN-1 (Compound 17) inhibits Aha1/Hsp90, preventing tau aggregation; IC50 = 3.32 μM.Formula:C22H17F3N4O2Colore e forma:SolidPeso molecolare:426.39Tubulin polymerization-IN-27
CAS:Compound 5j inhibits tubulin polymerization, arrests cell cycle at G2/M phase, and induces apoptosis.Formula:C22H20N2O2Colore e forma:SolidPeso molecolare:344.41GF 15
CAS:GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.Formula:C23H21ClO6Purezza:98%Colore e forma:SolidPeso molecolare:428.86OSIP-486823
CAS:OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.Formula:C29H28FNO4Purezza:98.59%Colore e forma:SolidPeso molecolare:473.54DJ101
CAS:DJ101: A stable tubulin inhibitor that bypasses multidrug resistance efflux pumps.Formula:C23H20N4O3Purezza:98%Colore e forma:SolidPeso molecolare:400.43Tubulin polymerization-IN-19
CAS:Tubulin aggregation-IN-19 (compound 4) is a potent tubulin aggregation inhibitor that has shown potential in breast cancer and drug-resistant colon cancer.Formula:C25H25NO5Colore e forma:SolidPeso molecolare:419.47Anticancer agent 49
CAS:Anticancer agent 49, also 69, hinders cell growth and microtubule aggregation, with potential in solid and blood cancer research.Formula:C26H25N3O4Colore e forma:SolidPeso molecolare:443.49TOK-8801
CAS:TOK-8801 is a dihydroimidazole thiazole carboxamide with immunomodulatory activity.Formula:C17H21N3OSPurezza:99.97%Colore e forma:SolidPeso molecolare:315.43
