Microtubulo associato
Gli inibitori delle proteine associate ai microtubuli prendono di mira le proteine che interagiscono con i microtubuli, i componenti strutturali del citoscheletro della cellula essenziali per la divisione cellulare. Queste proteine regolano la stabilità e la dinamica dei microtubuli durante la mitosi. L'inibizione delle proteine associate ai microtubuli può interrompere la funzione dei microtubuli, portando all'arresto del ciclo cellulare e all'apoptosi, in particolare nelle cellule tumorali a rapida divisione. Questi inibitori sono ampiamente utilizzati nella ricerca sul cancro e nello sviluppo di farmaci. Presso CymitQuimica, offriamo una gamma completa di inibitori di proteine associate ai microtubuli di alta qualità per supportare la tua ricerca sulla divisione cellulare, la dinamica del citoscheletro e la terapia del cancro.
Trovati 284 prodotti di "Microtubulo associato"
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Estramustine
CAS:Estramustine (LEO-275), a nitrogen mustard-estradiol compound, treats prostate cancer and protects against radiation.Formula:C23H31Cl2NO3Purezza:98.09%Colore e forma:SolidPeso molecolare:440.4Ref: TM-T20681
5mg47,00€10mg70,00€25mg126,00€50mg202,00€100mg329,00€200mg487,00€1mL*10mM (DMSO)50,00€Vindesine sulfate
CAS:Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.Formula:C43H57N5O11SPurezza:97.51%Colore e forma:Amorphous SolidPeso molecolare:8524-Isopropoxybenzoic acid
CAS:4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.Formula:C10H12O3Purezza:99.88%Colore e forma:White To Off-White PowderPeso molecolare:180.2Soblidotin
CAS:Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.Formula:C39H67N5O6Purezza:99.89%Colore e forma:SolidPeso molecolare:701.98N-Phenylbenzylamine
CAS:A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerizationFormula:C13H13NPurezza:98.75%Colore e forma:Colorless To Pale Yellow Crystalline PowderPeso molecolare:183.25Albendazole sulfoxide
CAS:Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.Formula:C12H15N3O3SPurezza:97.29%Colore e forma:White To Off-White PowderPeso molecolare:281.33Tau protein (592-597), Human TFA
Tau protein (592-597), Human (TFA) is a peptide fragment of human Tau protein.Formula:C36H63F3N10O11Purezza:>99.99%Colore e forma:SolidPeso molecolare:868.94TN-16
CAS:TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)Formula:C19H18N2O2Purezza:99.54%Colore e forma:SolidPeso molecolare:306.36Spastazoline
CAS:Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).Formula:C20H30N8Purezza:99.23%Colore e forma:SolidPeso molecolare:382.51Ref: TM-T8513
1mg35,00€5mg74,00€10mg111,00€25mg215,00€50mg324,00€100mg465,00€200mg645,00€1mL*10mM (DMSO)82,00€Curvulin
CAS:Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.Formula:C12H14O5Purezza:98.65%Colore e forma:SolidPeso molecolare:238.24Ref: TM-T36850
1mg145,00€5mg319,00€10mg472,00€25mg753,00€50mg1.074,00€100mg1.444,00€1mL*10mM (DMSO)284,00€Plinabulin
CAS:Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM).Formula:C19H20N4O2Purezza:98.69% - >99.99%Colore e forma:SolidPeso molecolare:336.39Tirbanibulin
CAS:Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Formula:C26H29N3O3Purezza:99.43% - 99.67%Colore e forma:SolidPeso molecolare:431.53Ref: TM-T6345
1mg35,00€5mg64,00€10mg77,00€25mg150,00€50mg266,00€100mg447,00€200mg640,00€1mL*10mM (DMSO)66,00€Suprafenacine
CAS:<p>Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces</p>Formula:C16H18N4OPurezza:99.91%Colore e forma:SolidPeso molecolare:282.34MAP4343
CAS:Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.Formula:C22H34O2Purezza:97.024%Colore e forma:SolidPeso molecolare:330.5MMAF
CAS:MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.Formula:C39H65N5O8Purezza:97.00% - 99.88%Colore e forma:SolidPeso molecolare:731.96LP-261
CAS:LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.Formula:C22H19N3O4SPurezza:99.91%Colore e forma:SolidPeso molecolare:421.47Ref: TM-T9595
1mg38,00€2mg49,00€5mg79,00€10mg119,00€25mg187,00€50mg354,00€100mg528,00€1mL*10mM (DMSO)87,00€D-64131
CAS:D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.Formula:C16H13NO2Purezza:99.48% - 99.67%Colore e forma:SolidPeso molecolare:251.28Clanfenur
CAS:Clanfenur belongs to a new group of substituted benzoylphenylureas. The drug shows both in vitro and in vivo antitumour activity.Formula:C16H15ClFN3O2Purezza:99.93%Colore e forma:SolidPeso molecolare:335.76Ref: TM-T5448
1mg37,00€5mg81,00€10mg116,00€25mg188,00€50mg284,00€100mg395,00€200mg560,00€1mL*10mM (DMSO)92,00€Valecobulin
CAS:Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.Formula:C26H28N6O5SPurezza:98%Colore e forma:SolidPeso molecolare:536.6NQTrp
CAS:NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.Formula:C21H16N2O4Purezza:98.35%Colore e forma:SolidPeso molecolare:360.36
