Microtubulo associato
Gli inibitori delle proteine associate ai microtubuli prendono di mira le proteine che interagiscono con i microtubuli, i componenti strutturali del citoscheletro della cellula essenziali per la divisione cellulare. Queste proteine regolano la stabilità e la dinamica dei microtubuli durante la mitosi. L'inibizione delle proteine associate ai microtubuli può interrompere la funzione dei microtubuli, portando all'arresto del ciclo cellulare e all'apoptosi, in particolare nelle cellule tumorali a rapida divisione. Questi inibitori sono ampiamente utilizzati nella ricerca sul cancro e nello sviluppo di farmaci. Presso CymitQuimica, offriamo una gamma completa di inibitori di proteine associate ai microtubuli di alta qualità per supportare la tua ricerca sulla divisione cellulare, la dinamica del citoscheletro e la terapia del cancro.
Trovati 283 prodotti di "Microtubulo associato"
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Phomopsin A
CAS:Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.Formula:C36H45ClN6O12Purezza:98%Colore e forma:SolidPeso molecolare:789.23Tubulin polymerization-IN-78
Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.Colore e forma:Odour SolidTBL-100
TBL-100 is a human monoclonal antibody (mAb) that targets Tau. It is applicable for research in Alzheimer's disease (AD) and progressive supranuclear palsy.Colore e forma:Odour LiquidAntiproliferative agent-66
Antiproliferative agent-66 (Compound B3) is an antiproliferative compound that induces apoptosis and causes cell cycle arrest. It demonstrates IC50 values ranging from 2.03 to 3.6 µM against SH-SY5Y neuroblastoma, HT-29 colorectal adenocarcinoma, and fibroblasts. Additionally, Antiproliferative agent-66 functions as a microtubule polymerization inhibitor with an IC50 of 0.79 µM.Formula:C18H15N3SColore e forma:SolidPeso molecolare:305.397Vinblastine
CAS:Vinblastine inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM, used to treat certain kinds of cancer.Formula:C46H58N4O9Purezza:97.42%Colore e forma:PowderPeso molecolare:810.97Breast cancer targeting peptide 18-4
CAS:Breastcancertargeting peptide 18–4 is a keratin 1 (KRT1) receptor-targeting peptide with a dissociation constant (Kd) of 0.98 μM. Its amino acid sequence is WxEAAYQrFL, and it is an analogue of the P160 peptide. When covalently bonded with the anticancer peptide MccJ25, it significantly enhances MccJ25 uptake in breast cancer cells and boosts its anticancer efficacy. The IC50 values for this covalent compound are 14.2, 20, and 25 μM against MCF-7, MDA-MB-435, and MDA-MB-435-MDR, respectively.Formula:C63H89N15O15Peso molecolare:1296.47PhosTAC7
CAS:PhosTAC7 successfully induced ternary protein complex formation of Halo-FOXO3a in a dose-dependent manner.Formula:C58H87ClN2O17Purezza:98.96%Colore e forma:SolidPeso molecolare:1119.77Ombrabulin hydrochloride
CAS:<p>Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and</p>Formula:C21H27ClN2O6Purezza:98%Colore e forma:SolidPeso molecolare:438.9Tirbanibulin dihydrochloride
CAS:Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formula:C26H31Cl2N3O3Purezza:98%Colore e forma:SolidPeso molecolare:504.45Trifluralin
CAS:<p>Trifluralin (Treflan) is an agricultural herbicide with mild toxicity. Trifluralin is a novel pollutant that can interfere with mitochondrial respiration.</p>Formula:C13H16F3N3O4Purezza:99.84%Colore e forma:Yellow-Orange Crystalline SolidPeso molecolare:335.28colchiceine
CAS:colchiceine has a wide range of applications in life science related research.Formula:C21H23NO6Purezza:99.38%Colore e forma:SolidPeso molecolare:385.41TTBK1-IN-1
CAS:TTBK1-IN-1 (compound 31) is a potent and selective TTBK1 inhibitor with CNS penetration that inhibits tau phosphorylation , Alzheimer's disease.Formula:C18H19N5O2Colore e forma:SolidPeso molecolare:337.38Amiprofos methyl
CAS:Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.Formula:C11H17N2O4PSPurezza:99.66%Colore e forma:SolidPeso molecolare:304.30BSc3094
CAS:BSc3094 is a potent Tau aggregation inhibitor that demonstrates the potential for Alzheimer's disease (AD) research.Formula:C17H12N6O3SColore e forma:SolidPeso molecolare:380.38Avanbulin
CAS:Avanbulin hinders tubulin polymerization, has unique antitumor properties, and is effective against various human tumors at low concentrations.Formula:C20H17N7O2Colore e forma:SolidPeso molecolare:387.39Oryzalin
CAS:Oryzalin is a selective pre-emergence herbicide belonging to the dinitroaniline class, which exerts its effect by inhibiting cell division in weeds.Formula:C12H18N4O6SPurezza:99.86%Colore e forma:SolidPeso molecolare:346.36Valecobulin
CAS:Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.Formula:C26H28N6O5SPurezza:98%Colore e forma:SolidPeso molecolare:536.6Vindesine sulfate
CAS:Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.Formula:C43H57N5O11SPurezza:97.51%Colore e forma:Amorphous SolidPeso molecolare:8524-Isopropoxybenzoic acid
CAS:4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.Formula:C10H12O3Purezza:99.88%Colore e forma:White To Off-White PowderPeso molecolare:180.2Spastazoline
CAS:Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).Formula:C20H30N8Purezza:99.23%Colore e forma:SolidPeso molecolare:382.51
