c-Myc
Gli inibitori di c-Myc prendono di mira la proteina c-Myc, un fattore di trascrizione che svolge un ruolo cruciale nella crescita cellulare, proliferazione e apoptosi. c-Myc regola l'espressione di numerosi geni coinvolti nel ciclo cellulare ed è spesso sovraespresso in vari tipi di cancro, portando a una proliferazione cellulare incontrollata e alla crescita tumorale. L'inibizione di c-Myc può interrompere questi processi, inducendo l'arresto del ciclo cellulare e l'apoptosi nelle cellule tumorali. Gli inibitori di c-Myc sono strumenti importanti nella ricerca sul cancro e nello sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori di c-Myc di alta qualità per supportare la tua ricerca in oncologia, regolazione del ciclo cellulare e controllo trascrizionale.
Trovati 69 prodotti di "c-Myc"
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Ceramides Mixture
CAS:<p>Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.</p>Formula:C36H71NO4Purezza:98%Colore e forma:SolidPeso molecolare:581.967FIDAS-5
CAS:<p>FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.</p>Formula:C15H13ClFNPurezza:97.66% - 98.3%Colore e forma:SolidPeso molecolare:261.72Eragidomide
CAS:<p>Eragidomide (Cereblon modulator 1) is a CRBN E3 ligase modulator, specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.</p>Formula:C22H18ClF2N3O4Purezza:97.51% - 99.63%Colore e forma:SolidPeso molecolare:461.85MYCi361
CAS:<p>MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).</p>Formula:C26H16ClF9N2O2Purezza:99.52%Colore e forma:SolidPeso molecolare:594.86MYCMI-6
CAS:<p>MYCMI-6 inhibits MYC:MAX, reduces tumor growth, triggers apoptosis, minimal side effects.</p>Formula:C20H19N7OPurezza:99.23%Colore e forma:SolidPeso molecolare:373.41MYCi975
CAS:<p>MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.</p>Formula:C25H16Cl2F6N2O2Purezza:99.3% - 99.82%Colore e forma:SolidPeso molecolare:561.3Saxagliptin hydrate
CAS:<p>Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).</p>Formula:C18H25N3O2·H2OPurezza:99.52%Colore e forma:SolidPeso molecolare:333.43KJ Pyr 9
CAS:<p>KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).</p>Formula:C22H15N3O4Purezza:99.56% - ≥98%Colore e forma:SolidPeso molecolare:385.37FIDAS-3
CAS:<p>FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities</p>Formula:C16H15F2NPurezza:97.75%Colore e forma:SolidPeso molecolare:259.29APTO-253
CAS:<p>APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells.</p>Formula:C22H14FN5Purezza:98.73%Colore e forma:SolidPeso molecolare:367.38c-Myc inhibitor 10
CAS:<p>c-Myc inhibitor 10 enhances cell potency with improved permeability from methylated morpholine nitrogen.</p>Formula:C28H38N6O3Colore e forma:SolidPeso molecolare:506.64c-Myc inhibitor 5
<p>DA3: Fluorescent c-Myc inhibitor, targets c-MYC G-quadruplex (K D 16 μM), selective, suppresses c-MYC expression.</p>Formula:C30H46N12Colore e forma:SolidPeso molecolare:574.77Anti-c-myc Antibody (9E10)
<p>Anti-c-myc Antibody (9E10) is a chimeric mouse IgG1 antibody targeting human c-myc.</p>Colore e forma:Odour LiquidAnticancer agent 263
<p>Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.</p>Formula:C13H20N2O6Colore e forma:SolidPeso molecolare:300.308Cotylenin A
CAS:<p>Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.</p>Formula:C33H50O11Colore e forma:SolidPeso molecolare:622.744H122
<p>H122 is a TEADPROTAC degrader effective in degrading TEAD1 with a DC50 of 3 nM, and it shows strong affinity for TEAD2, TEAD3, and TEAD4 with Ki values of 2.0, 3.6, and 1.6 nM, respectively. H122 also downregulates Myc expression and inhibits the growth of MSTO-211H and NCI-H226 cells, with IC50 values of 21.3 nM and 0.6 nM, respectively, demonstrating antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligaseCereblon)</p>Formula:C45H45ClFN5O8Colore e forma:SolidPeso molecolare:838.319Methylcarbamyl PAF C-8
<p>Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.</p>Colore e forma:Odour SolidRA-V
<p>RA-V is a natural product that can be used as a reference standard.</p>Formula:C160H202N24O41Colore e forma:SolidPeso molecolare:3117.5VGN50
<p>VGN50 is a bioactive molecule that mimics the function of K-Rta, capable of downregulating MYC-mediated gene transcription. VGN50 exhibits antitumor activity.</p>Formula:C121H218N46O32Peso molecolare:2827.68453MYC-IN-2
CAS:<p>MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.</p>Formula:C25H17N3O2SColore e forma:SolidPeso molecolare:423.49
