c-Myc
Gli inibitori di c-Myc prendono di mira la proteina c-Myc, un fattore di trascrizione che svolge un ruolo cruciale nella crescita cellulare, proliferazione e apoptosi. c-Myc regola l'espressione di numerosi geni coinvolti nel ciclo cellulare ed è spesso sovraespresso in vari tipi di cancro, portando a una proliferazione cellulare incontrollata e alla crescita tumorale. L'inibizione di c-Myc può interrompere questi processi, inducendo l'arresto del ciclo cellulare e l'apoptosi nelle cellule tumorali. Gli inibitori di c-Myc sono strumenti importanti nella ricerca sul cancro e nello sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori di c-Myc di alta qualità per supportare la tua ricerca in oncologia, regolazione del ciclo cellulare e controllo trascrizionale.
Trovati 76 prodotti di "c-Myc"
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MYCi975
CAS:MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.Formula:C25H16Cl2F6N2O2Purezza:99.3% - 99.82%Colore e forma:SolidPeso molecolare:561.3FIDAS-5
CAS:FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.Formula:C15H13ClFNPurezza:98.3% - 99.17%Colore e forma:SolidPeso molecolare:261.72Ref: TM-T11285
1mg59,00€2mg85,00€5mg116,00€10mg187,00€25mg331,00€50mg512,00€100mg740,00€500mg1.415,00€Eragidomide
CAS:Eragidomide (Cereblon modulator 1) is a CRBN E3 ligase modulator, specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.Formula:C22H18ClF2N3O4Purezza:97.51% - 99.63%Colore e forma:SolidPeso molecolare:461.85Ref: TM-T10765
1mg38,00€5mg82,00€10mg133,00€25mg269,00€50mg442,00€100mg595,00€200mg802,00€1mL*10mM (DMSO)84,00€Saxagliptin hydrate
CAS:Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).Formula:C18H25N3O2·H2OPurezza:99.52%Colore e forma:SolidPeso molecolare:333.43MYCi361
CAS:MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).Formula:C26H16ClF9N2O2Purezza:99.52%Colore e forma:SolidPeso molecolare:594.86Ceramides Mixture
CAS:Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.Formula:C36H71NO4Purezza:98%Colore e forma:SolidPeso molecolare:581.967MYCMI-6
CAS:MYCMI-6 inhibits MYC:MAX, reduces tumor growth, triggers apoptosis, minimal side effects.Formula:C20H19N7OPurezza:99.23%Colore e forma:SolidPeso molecolare:373.41Ref: TM-T12134
1mg71,00€5mg152,00€10mg222,00€25mg358,00€50mg512,00€100mg707,00€200mg973,00€500mg1.431,00€KJ Pyr 9
CAS:KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).Formula:C22H15N3O4Purezza:99.56% - ≥98%Colore e forma:SolidPeso molecolare:385.37Ref: TM-T15665
2mg37,00€5mg54,00€10mg77,00€25mg138,00€50mg264,00€100mg482,00€200mg647,00€500mg1.009,00€1mL*10mM (DMSO)59,00€FIDAS-3
CAS:FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activitiesFormula:C16H15F2NPurezza:97.75%Colore e forma:SolidPeso molecolare:259.29Ref: TM-T11284
5mg49,00€10mg73,00€25mg127,00€50mg182,00€100mg264,00€200mg354,00€1mL*10mM (DMSO)48,00€APTO-253
CAS:APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells.Formula:C22H14FN5Purezza:98.73%Colore e forma:SolidPeso molecolare:367.38Ref: TM-T10352
1mg40,00€2mg52,00€5mg75,00€10mg96,00€25mg170,00€50mg255,00€100mg371,00€1mL*10mM (DMSO)84,00€PROTAC MTP3 degrade-1
PROTACMTP3 degrade-1 is a PROTAC degrader for MYC.Formula:C44H38N6O8Colore e forma:SolidPeso molecolare:778.27511c-Myc inhibitor 10
CAS:c-Myc inhibitor 10 enhances cell potency with improved permeability from methylated morpholine nitrogen.Formula:C28H38N6O3Colore e forma:SolidPeso molecolare:506.64Anticancer agent 263
Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.Formula:C13H20N2O6Colore e forma:SolidPeso molecolare:300.308c-Myc inhibitor 7
CAS:c-Myc inhibitor 7 degrades c-MYC, CK1α, GSPT1, IKZF1/2/3 proteins in tumors, for research on related diseases.Formula:C35H30N6O5Colore e forma:SoildPeso molecolare:614.65H122
H122 is a TEADPROTAC degrader effective in degrading TEAD1 with a DC50 of 3 nM, and it shows strong affinity for TEAD2, TEAD3, and TEAD4 with Ki values of 2.0, 3.6, and 1.6 nM, respectively. H122 also downregulates Myc expression and inhibits the growth of MSTO-211H and NCI-H226 cells, with IC50 values of 21.3 nM and 0.6 nM, respectively, demonstrating antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligaseCereblon)Formula:C45H45ClFN5O8Colore e forma:SolidPeso molecolare:838.319VTX-0811
VTX-0811 is a human IgG4 monoclonal antibody (mAb) that targets PSGL1/CD162. It modulates immune signaling pathways by enhancing TNF-α/NF-κB and chemokine-mediated signaling while reducing oxidative phosphorylation, fatty acid metabolism, and Myc signaling. VTX-0811 increases the proportion of CD8+ T cells among infiltrating T cells and exhibits antitumor activity in humanized mouse PDX models of melanoma.Colore e forma:Odour LiquidVGN50
VGN50 is a bioactive molecule that mimics the function of K-Rta, capable of downregulating MYC-mediated gene transcription. VGN50 exhibits antitumor activity.Formula:C121H218N46O32Peso molecolare:2827.68453RA-V
RA-V is a natural product that can be used as a reference standard.Formula:C160H202N24O41Colore e forma:SolidPeso molecolare:3117.5c-Myc inhibitor 13
c-Myc inhibitor13 (compound A6) is an inhibitor of c-MYC transcription. It selectively stabilizes c-MYCG4 and inhibits G4-related c-MYC transcription.Formula:C30H39N9OPeso molecolare:541.32776Methylcarbamyl PAF C-8
Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.Colore e forma:Odour Solid
