Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2526 prodotti di "Cromatina/Epigenetica"
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MK-5108
CAS:MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formula:C22H21ClFN3O3SPurezza:99.22%Colore e forma:SolidPeso molecolare:461.94SCH-1473759 hydrochloride
CAS:SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Formula:C20H27ClN8OSPurezza:98.29%Colore e forma:SolidPeso molecolare:463Ref: TM-T12864
2mg361,00€5mgPrezzo su richiesta10mgPrezzo su richiesta1mL*10mM (DMSO)Prezzo su richiestaDehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formula:C22H24N2O7Purezza:99.79% - 99.92%Colore e forma:SolidPeso molecolare:428.44Ref: TM-T2S2362
1mg94,00€5mg216,00€10mg354,00€25mg582,00€50mg825,00€100mg1.111,00€200mg1.491,00€1mL*10mM (DMSO)255,00€GSK2807 Trifluoroacetate
CAS:GSK2807 Trifluoroacetate is a selective and SAM-competitive inhibitor of SMYD3 (Ki: 14 nM; IC50: 130 nM).Formula:C21H33F3N8O7Purezza:99.95%Colore e forma:SolidPeso molecolare:566.53NVP-BSK805
CAS:NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.Formula:C27H28F2N6OPurezza:98%Colore e forma:SolidPeso molecolare:490.55(R)-Dihydrolipoic acid
CAS:(R)-Dihydrolipoic acid, the biochemically significant R-enantiomer, partakes in biochemical transformations.Formula:C8H16O2S2Purezza:98%Colore e forma:SolidPeso molecolare:208.33Tazemetostat trihydrochloride
CAS:Tazemetostat trihydrochloride, an EZH2 inhibitor, orally active, IC50: 4nM (rat), Ki: 2.5nM (human), effective in peptide and nucleosome assays.Formula:C34H47Cl3N4O4Purezza:98%Colore e forma:SolidPeso molecolare:682.12Acedapsone
CAS:Acedapsone has antimalarial and antimicrobial action, but is mainly used as a depot leprostatic agent.Formula:C16H16N2O4SPurezza:98%Colore e forma:SolidPeso molecolare:332.37TETi76
CAS:TETi76 is an orally active inhibitor from the TET family, demonstrating IC50 values of 1.5, 9.4, and 8.8 μM against TET1, TET2, and TET3, respectively. The compound competitively binds to the active sites of TET enzymes, reducing cytosine hydroxymethylation and restricting clonal growth in mutated TET2 in vitro and in vivo, without affecting the growth of normal hematopoietic progenitor cells. TETi76 is utilized in leukemia research.Formula:C10H16O5Colore e forma:SolidPeso molecolare:216.232-PADQZ
CAS:DPQ is an antiviral compound.Formula:C14H19N5O2Purezza:98%Colore e forma:White PowderPeso molecolare:289.33Diethyl bipy55'DC
CAS:"Diethyl bipy55'DC blocks CP4H, crucial for collagen stability via hydroxylation in cells."
Formula:C16H16N2O4Purezza:98%Colore e forma:SolidPeso molecolare:300.31193 D7
CAS:193 D7 is an inhibitor of histone demethylase JMJD1C (IC50= 0.59 μM in in vitro demethylation assay). In vivo, 193 D7 suppresses tumors by targeting intratumoral Treg cells in mouse tumor models.Formula:C16H15NO4SColore e forma:SolidPeso molecolare:317.36GSK 4027
CAS:GSK 4027 is a PCAF/GCN5 bromodomain chemical probe. In a time-resolved fluorescence resonance energy transfer (TR-FRET) assay, it has a pIC50 of 7.4±0.11 for PCAF.Formula:C17H21BrN4OColore e forma:SolidPeso molecolare:377.28Nicotinamide-d4
CAS:Nicotinamide-d4 is a deuterium-labelled compound of nicotinamide for isotope tracing. Nicotinamide, a vitamin B3 derivative, inhibits SIRT1 and SIRT2.Formula:C6H2D4N2OPurezza:99.746%Colore e forma:SolidPeso molecolare:126.15CrBKA
CAS:CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity [1] .Formula:C28H31N3O6Colore e forma:SolidPeso molecolare:505.56GSK-J1 lithium salt
CAS:GSK-J1 lithium salt is an effective inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with an IC 50 of 60 nM for KDM6B.Formula:C22H22LiN5O2Purezza:98%Colore e forma:SolidPeso molecolare:395.38KR-39038
CAS:KR-39038 is an oral GRK5 inhibitor for heart failure research; blocks HDAC5 pathway, IC50: 0.02 μM, fights cardiac hypertrophy.Formula:C24H32ClFN6OColore e forma:SolidPeso molecolare:475.00Asteltoxin
CAS:Asteltoxin is a useful organic compound for research related to life sciences. The catalog number is T124203 and the CAS number is 79663-49-3.Formula:C23H30O7Colore e forma:SolidPeso molecolare:418.486HDAC6-IN-27
CAS:HDAC6-IN-27 (compound 8C), an HDAC inhibitor, exhibits IC 50 values of 15.9 nM, 136.5 nM, and 6180.2 nM against HDAC6, HDAC8, and HDAC1, respectively. It also demonstrates potent antiparasitic effects [1].Formula:C15H15N3O4Colore e forma:SolidPeso molecolare:301.3BChE/HDAC6-IN-2
CAS:BChE/HDAC6-IN-2 is an inhibitor of BChE and HDAC6 with neuroprotective and ROS scavenging activity and a metal ion co-agonist and inhibits tau phosphorylation.Formula:C27H30N4O4Purezza:98.47%Colore e forma:SoildPeso molecolare:474.55BG47
CAS:BG47: a COMET probe for precise optical epigenetic control, inhibits histone deacetylases with light.Formula:C25H22N4O2SColore e forma:SolidPeso molecolare:442.54Guanosine-5'-triphosphate disodium salt
CAS:5'-GTP disodium salt boosts myogenic differentiation and fuels cellular processes.Formula:C10H14N5Na2O14P3Purezza:95.69% - 99.96%Colore e forma:Odorless White SolidPeso molecolare:567.14BRD 4354 ditrifluoroacetate
BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 μM).Formula:C25H25ClF6N4O5Purezza:98%Colore e forma:SolidPeso molecolare:610.93AdipoR agonist 1
CAS:AdipoR agonist 1 (Compound 112254), acting as an agonist for the adiponectin receptor (AdipoR), stimulates transcriptional regulators including peroxisome proliferator-activated receptors (PPARs), peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α), sirtuin 1 (SIRT1), and adenylate-activated protein kinase (AMPK). It is employed in the field of preventive doping research.Formula:C26H35N3O3Colore e forma:SolidPeso molecolare:437.57BG48
CAS:BG48, a COMET probe, enables precise optical epigenetic control and photochromically blocks human histone deacetylases with visible light.Formula:C25H23N5OSColore e forma:SolidPeso molecolare:441.55I-BET787
CAS:I-BET787, an orally active pan-BET bromodomain inhibitor, has demonstrated efficacy in murine inflammation models.Formula:C16H20ClN3O2Colore e forma:SolidPeso molecolare:321.80KAT6-IN-1
CAS:KAT6-IN-1 (compound E) is a selective, orally available inhibitor of histone acetyltransferases KAT6A and KAT6B, exhibiting antitumour activity for cancer.Formula:C19H18N4O5SPurezza:99.86%Colore e forma:SolidPeso molecolare:414.43BG14
CAS:BG14: High-res optical epigenetic control; photo-inhibits human histone deacetylases with visible light.Formula:C21H21N5OColore e forma:SolidPeso molecolare:359.433(3S,4S)-Tofacitinib
CAS:(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.Formula:C16H20N6OPurezza:98%Colore e forma:SolidPeso molecolare:312.37ZM39923
CAS:ZM39923 is a JAK3 inhibitor (pIC50: 7.1). ZM39923 also effectively inhibits tissue transglutaminase (IC50: 10 nM).Formula:C23H25NOPurezza:98%Colore e forma:SolidPeso molecolare:331.45HDAC2-IN-2
CAS:HDAC2-IN-2 (compound 124) acts as an HDAC2 inhibitor, exhibiting a Kd value ranging from 0.1-1 μM.Formula:C18H15N3O3SColore e forma:SolidPeso molecolare:353.40TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Formula:C26H25ClF3N5O3Purezza:99.73%Colore e forma:SolidPeso molecolare:547.96Ref: TM-T6039
1mg38,00€5mg80,00€10mg120,00€25mg216,00€50mg354,00€100mg512,00€200mg727,00€1mL*10mM (DMSO)96,00€TMPA
CAS:TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.Formula:C21H32O6Purezza:99.21%Colore e forma:SolidPeso molecolare:380.48Ref: TM-T13173
1mg75,00€5mg164,00€10mg260,00€25mg440,00€50mg620,00€100mg964,00€1mL*10mM (DMSO)167,00€E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Formula:C21H30O6Purezza:99.52%Colore e forma:SolidPeso molecolare:378.46GW843682X
CAS:GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).Formula:C22H18F3N3O4SPurezza:99.92%Colore e forma:SolidPeso molecolare:477.46MY-1B
CAS:MY-1B is a nitrogen-substituted butenamide stereoprobe that blocks stereoselective enrichment of NSUN2, binding selectively to the C271 of NSUN2.Formula:C22H18BrN3O2Purezza:99.81% - >99.99%Colore e forma:SoildPeso molecolare:436.3UNC0224
CAS:UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.Formula:C26H43N7O2Purezza:99.80%Colore e forma:SolidPeso molecolare:485.67Ref: TM-T17203
1mg51,00€2mg73,00€5mg97,00€10mg159,00€25mg354,00€50mg558,00€100mg797,00€500mg1.634,00€1mL*10mM (DMSO)107,00€GSK-1268997
CAS:GSK-1268997 is a bio-active chemical.Formula:C21H23N7O3SPurezza:99.33% - 99.81%Colore e forma:SolidPeso molecolare:453.52Phorbol 12,13-dibutyrate
CAS:Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.Formula:C28H40O8Purezza:99.32% - 99.37%Colore e forma:SolidPeso molecolare:504.61Ref: TM-T16526
1mg58,00€5mg160,00€10mg268,00€25mg530,00€50mg827,00€100mg1.314,00€200mg1.773,00€1mL*10mM (DMSO)170,00€LY 170198
CAS:LY 170198 is a protein kinase C inhibitor.Formula:C22H25N5O5Purezza:98%Colore e forma:SolidPeso molecolare:439.46TM6089
CAS:TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.Formula:C13H14N4O3SPurezza:99.70%Colore e forma:SolidPeso molecolare:306.34Ref: TM-T17105
1mg52,00€5mg115,00€10mg167,00€25mg301,00€50mg452,00€100mg658,00€200mg884,00€1mL*10mM (DMSO)123,00€DHPCC-9
CAS:DHPCC-9 is an inhibitor of Pim kinase.Formula:C15H10N2OColore e forma:SolidPeso molecolare:234.25DC_501
CAS:DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.Formula:C25H23Cl2N3OPurezza:98%Colore e forma:SolidPeso molecolare:452.38DCE_254
CAS:DCE_254 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.Formula:C21H17N9OSPurezza:98%Colore e forma:SolidPeso molecolare:443.48Langkamide
CAS:Langkamide is a HIF-2 inhibitor with EC₅₀ values of 14.0 uM.Formula:C16H17NO5Purezza:98%Colore e forma:SolidPeso molecolare:303.31MAT2A-IN-5
CAS:MAT2A-IN-5 inhibits MAT2A in tumors, curbing growth in gastric, colon, liver, and pancreatic cancers.Formula:C17H12ClF3N2OColore e forma:SolidPeso molecolare:352.74BF1
CAS:BF1 is an inhibitor of HAT (histone acetyltransferase) active both in vitro and in vivo.Formula:C12H12ClN3SColore e forma:SolidPeso molecolare:265.76Farnesylthiotriazole
CAS:Farnesylthiotriazole is a persistent PKC activator agent.Formula:C17H27N3SPurezza:98%Colore e forma:SolidPeso molecolare:305.48Tenovin-D3
CAS:Tenovin-D3 is a sirtuin SirT2 inhibitor. It acts by increasing p21 (CDKN1A) expression in a p53-independent manner.Formula:C22H27Cl3N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:533.9ML399
CAS:ML399 inhibits menin–MLL interaction, selectively blocking oncogenic MLL signaling in leukemia cells, supporting functional genomics and therapeutic research.Formula:C27H28FN3O2Purezza:97.84% - 98.20%Colore e forma:SolidPeso molecolare:445.53HIF-IN-33
CAS:HIF-IN-33 is an inhibitor of HIF pathway.Formula:C21H17F3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:414.38BET-BAY 002
CAS:BET-BAY 002 is an effective BET bromodomain inhibitor demonstrating efficacy in vivo and in vitro against multiple myeloma and leukaemia models.Formula:C22H18ClN5OColore e forma:SolidPeso molecolare:403.86Fagaronine chloride
CAS:Fagaronine chloride is a potent inhibitor of Topoisomerases I.Formula:C21H20ClNO4Colore e forma:SolidPeso molecolare:385.84Lobelane Hydrochloride
CAS:Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor.Formula:C22H30ClNColore e forma:SolidPeso molecolare:343.93AMPK activator 8
CAS:AMPK activator 8 targets rAMPK α1β1γ1/α2β1γ1/α1β2γ1 (EC50: 11/27/4 nM) for type 2 diabetes research.Formula:C25H21ClN2O6Colore e forma:SolidPeso molecolare:480.9SirReal-1
CAS:SirReal-1 is an effective and selective inhibitor of Sirt2.Formula:C18H18N4OS2Purezza:98%Colore e forma:SolidPeso molecolare:370.49Prospasmine
CAS:Prospasmine is an anticholinergic.Formula:C17H28ClNO2Purezza:98%Colore e forma:SolidPeso molecolare:313.87Ilorasertib hydrochloride
CAS:Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:Formula:C25H22ClFN6O2SPurezza:98.45%Colore e forma:SolidPeso molecolare:525Hns 32
CAS:Hns 32 possesses antiarrhythmic properties in dog and guinea pig hearts. It also has vasodilator action.Formula:C24H29N3Purezza:98%Colore e forma:SolidPeso molecolare:359.51ZL0454
CAS:ZL0454 is an effective and selective Bromodomain-containing protein 4 inhibitors (IC50: 49 and 32 nM for BD1 and BD2).Formula:C18H22N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:374.46LP99
CAS:LP99 is an epigenetic probe.Formula:C26H30ClN3O4SPurezza:99.74%Colore e forma:SolidPeso molecolare:516.05Ref: TM-T15784
1mg43,00€5mg96,00€10mg145,00€25mg305,00€50mg442,00€100mgPrezzo su richiesta1mL*10mM (DMSO)97,00€CTPB
CAS:CTPB is a potent p300 histone acetyltransferase (HAT) activator that can be used in the preparation of hair growth promoters and/or hair loss treatments.Formula:C31H43ClF3NO2Purezza:99.51%Colore e forma:SolidPeso molecolare:554.13DM-01
CAS:DM-01 is a potent and selective inhibitor of EZH2.
Formula:C23H24F3N3O2Colore e forma:SolidPeso molecolare:431.45HDAC1-IN-4
CAS:HDAC1-IN-4 is a potent inhibitor of Plasmodium falciparum HDAC1 (PfHDAC1) with low cytotoxicity and antimalarial effects (IC50<5 nM).Formula:C21H24BrClN6O2Colore e forma:SolidPeso molecolare:507.82F-amidine
CAS:F-amidine is a bioavailable irreversible PAD4 inactivator.Formula:C14H19FN4O2Colore e forma:SolidPeso molecolare:294.32Piribedil Maleate
CAS:Piribedil Maleate is a direct agonist of dopamine that acts by showing selectivity for the D3 subtype.Formula:C20H22N4O6Purezza:98%Colore e forma:SolidPeso molecolare:414.41OICR-0547
CAS:OICR-0547 is an inactive derivative of OICR-9429 and is commonly used as a negative control for OICR-9429.Formula:C28H29F3N4O4Purezza:98%Colore e forma:SolidPeso molecolare:542.55UNC0379 TFA
CAS:UNC0379 TFA inhibits SETD8 (IC50: 7.3 μM), selective for 15+ methyltransferases.Formula:C25H36F3N5O4Colore e forma:SolidPeso molecolare:527.589AC430
CAS:AC430, a specific JAK2 inhibitor for cancer and autoimmune therapy, excels in preclinical trials with low doses. Developed by Ambit.Formula:C19H16FN5OColore e forma:SolidPeso molecolare:349.36ZIKV-IN-2
CAS:ZIKV-IN-2 blocks ZIKV replication, is a strong NS5 MTase inhibitor (IC50: 38.86 μM), and aids Zika virus research.Formula:C39H42O4Colore e forma:SolidPeso molecolare:574.75NCD38
CAS:NCD38 is a potent, selective LSD1 inhibitor.Formula:C37H37ClF3N3O4Purezza:98.21% - 98.86%Colore e forma:SolidPeso molecolare:680.16DDO-2093 dihydrochloride
DDO-2093 dihydrochloride: potent MLL1-WDR5 inhibitor, IC50=8.6 nM, Kd=11.6 nM, antitumor.Formula:C29H39Cl3FN9O3Colore e forma:SolidPeso molecolare:687.04SPC-180002
CAS:SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively.Formula:C18H23NO4Purezza:98%Colore e forma:SolidPeso molecolare:317.38Helenalin Acetate
CAS:Helenalin Acetate: anti-inflammatory, anti-cancer, hinders C/EBPß and p300 cooperation.Formula:C17H20O5Purezza:98%Colore e forma:SolidPeso molecolare:304.34NSC 698600
CAS:NSC 698600 is a potent inhibitor of PCAF(p300/CBP-associated factor) with IC 50 of 6.51 μM that shows good inhibition activity of cancer cell proliferation [1].Formula:C14H12N2O2SColore e forma:SolidPeso molecolare:272.32NSD3-IN-2
CAS:NSD3-IN-2: Potent NSD3 inhibitor, IC50 17.97μM, halts NSCLC growth (H460, H1299, H1650) with anticancer effects.Formula:C17H15N5OSColore e forma:SolidPeso molecolare:337.4CX-6258
CAS:CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.Formula:C26H24ClN3O3Purezza:97.46%Colore e forma:SolidPeso molecolare:461.94Ref: TM-T1834
1mg34,00€5mg75,00€10mg101,00€25mg197,00€50mg295,00€100mg447,00€200mg623,00€1mL*10mM (DMSO)77,00€BAY-6035-R-isomer
CAS:BAY-6035 is an inhibitor of the methylation of MEKK2 peptide.Formula:C22H28N4O3Colore e forma:SolidPeso molecolare:396.48PARP-2/1-IN-2
CAS:PARP-2/1-IN-2, Veliparib's enantiomer, inhibits PARP-1/2 (Ki: 5/2 nM) with 3 nM EC50 in cell assay.Formula:C13H16N4OColore e forma:SolidPeso molecolare:244.29DS-437
CAS:DS-437 is a dual PRMT5/7 inhibitor (IC50s: 6 μM). DS-437 also inhibits DNMT3A and DNMT3B (IC50s: 52 and 62 μM). DS-437 inhibits the methylation of FOXP3.Formula:C15H23N7O4SPurezza:98%Colore e forma:SolidPeso molecolare:397.45HIF-1α inhibitor-1
CAS:HIF-1α inhibitor-1 is a HIF-1 alpha inhibitor.Formula:C15H11N3O4Colore e forma:SolidPeso molecolare:297.27TFMB-(S)-2-HG
CAS:TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase.Formula:C13H11F3O4Purezza:98.07%Colore e forma:SolidPeso molecolare:288.22Ref: TM-T24871
2mg34,00€5mg50,00€10mg79,00€25mg146,00€50mg227,00€100mg339,00€500mg713,00€1mL*10mM (DMSO)49,00€PI3K/Akt/CREB activator 1
CAS:PI3K/Akt/CREB activator 1 (AE-18) is an iNOS inhibitor that can be used to study vascular dementia and Parkinson's.Formula:C19H15F4NO3Colore e forma:SolidPeso molecolare:381.32DPQ
CAS:DPQ inhibits PARP-1, aids in neuroprotection, restores ATP, and lessens neuronal injury from NMDA.
Formula:C18H26N2O2Purezza:98%Colore e forma:SolidPeso molecolare:302.41JAK3-IN-1
CAS:JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune system disorders.Formula:C26H30ClN7O2Colore e forma:SolidPeso molecolare:508.02BAY-598 R-isomer
CAS:BAY-598 R-isomer, a SMYD2-selective inhibitor, is the R-enantiomer of BAY589, not targeting PAR1.Formula:C22H20Cl2F2N6O3Colore e forma:SolidPeso molecolare:525.34CPI-455 HCl
CAS:CPI-455: specific KDM5A inhibitor, IC50=10±1nM, increases H3K4me3, reduces DTPs in cancer cells.Formula:C16H15ClN4OPurezza:98%Colore e forma:SolidPeso molecolare:314.77BRD4 Inhibitor-19
CAS:BRD4 inhibitors -19 are BET inhibitors that act on BRD4-BD1 (IC50: 55 nM) and can be used to study multiple myeloma.Formula:C29H25N5O3Colore e forma:SolidPeso molecolare:491.54Thi-DPPY
CAS:Thi-DPPY: Potent JAK3/BTK inhibitor (IC50: 1.38/62.4 nM), anti-proliferative, anti-inflammatory, potential in IPF research.Formula:C28H28ClN5O4SColore e forma:SolidPeso molecolare:566.07LT052
CAS:LT052 is a BET BD1 inhibitor with anti-inflammatory activity. It mediates the BRD4/NF-κB/NLRP3 signaling inflammatory pathway.Formula:C22H19N5O4SPurezza:98.82%Colore e forma:SolidPeso molecolare:449.48SIRT5 inhibitor 4
CAS:SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitorand no inhibitory effect on SIRT1/2/3,anticancer.Formula:C18H15N3O4SPurezza:99.97%Colore e forma:SolidPeso molecolare:369.39WD2000-012547
CAS:WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).Formula:C17H14N2OPurezza:98%Colore e forma:SolidPeso molecolare:262.31UNC6212 (Kme2)
UNC6212 (Kme2), a dimethyllysine (Kme2)-containing ligand, has a K D for CBX5 of 5.7 μM .Formula:C39H53N7O11Colore e forma:SolidPeso molecolare:795.88PIM1-IN-6
CAS:PIM1-IN-6 (5h) inhibits PIM-1 (IC50: 0.60 μM) and is cytotoxic to HCT-116 (IC50: 1.51 μM) and MCF-7 cells (IC50: 15.2 μM).Formula:C21H18N6O4Colore e forma:SolidPeso molecolare:418.41GS-626510
CAS:GS-626510 is an orally bioavailable inhibitor of BET family bromodomains (Kd: 0.59-3.2 nM for BRD2/3/4; IC50: 83 nM and 78 nM for BD1 and BD2).Formula:C25H22N4OColore e forma:SolidPeso molecolare:394.47YM-53601
CAS:YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.Formula:C21H22ClFN2OPurezza:99.65%Colore e forma:SolidPeso molecolare:372.86SIRT5 inhibitor 6
CAS:SIRT5 inhibitor 6 is Sirtuin 5 inhibitor for sepsis-associated acute kidney injury (AKI) modulates protein succinylation and pro-inflammatory cytokine release.Formula:C21H28N6O4SPurezza:99.84%Colore e forma:SolidPeso molecolare:460.55IACS-9571
CAS:IACS-9571 is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).Formula:C32H42N4O8SPurezza:98%Colore e forma:SolidPeso molecolare:642.76Dot1L-IN-5
CAS:Dot1L-IN-5 is a potent inhibitor of the disruptor of telomeric silencing 1-like protein ( DOT1L ) with an IC 50 SPA DOT1L of 0.17 nM [1].Formula:C23H19ClF2N8O5SColore e forma:SolidPeso molecolare:592.96GNA002
CAS:GNA002 is a highly potent, specific, and covalent EZH2 (Enhancer of zeste homolog 2) inhibitor (IC50: 1.1 μM).Formula:C42H55NO8Purezza:98%Colore e forma:SolidPeso molecolare:701.89
