Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2442 prodotti di "Cromatina/Epigenetica"
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YM-53601 free base
CAS:YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents.Formula:C21H21FN2OPurezza:98%Colore e forma:SolidPeso molecolare:336.4EP009
CAS:EP009, a novel, selective, and orally active inhibitor of JAK3, induces therapeutic response in T-cell malignancies.Formula:C14H24O2Colore e forma:SolidPeso molecolare:224.34MDK8228
CAS:MDK8228 is an inhibitor of CBP/p300 and BRD4 bromodomain. MDK8228 downregulates IL-6, IL-ß and IFN-ß in macrophages.Formula:C31H41N5O3Colore e forma:SolidPeso molecolare:531.69DDP-38003 dihydrochloride
CAS:DDP-38003 dihydrochloride is an orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor (IC50: 84 nM).Formula:C21H28Cl2N4OPurezza:99.76%Colore e forma:SolidPeso molecolare:423.38RM65
CAS:RM65 is an arginine methyltransferase inhibitor.Formula:C34H32N2O4S2Purezza:98%Colore e forma:SolidPeso molecolare:596.76M-110
CAS:M-110 selectively targets PIM kinases, best at PIM-3 (IC50=47nM), and inhibits prostate cancer cell growth (IC50=0.6-0.9μM).Formula:C22H28ClN5O3Purezza:99.55%Colore e forma:SolidPeso molecolare:445.94Ref: TM-T15830
5mg64,00€10mg92,00€25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)64,00€AZD-1897
CAS:AZD-1897 is a highly efficient ATP-competitive pan-PIM inhibitor with anti-cancer and anti-leukemia activity, used in multiple myeloma research.Formula:C18H23N3O3SPurezza:99.49%Colore e forma:SolidPeso molecolare:361.46p32 Inhibitor M36
CAS:p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.Formula:C23H28N8O2Purezza:98%Colore e forma:SolidPeso molecolare:448.52CEP-8983
CAS:CEP-8983 is a PARP inhibitor potentially for the treatment of solid tumours.Formula:C18H14N2O3Purezza:98%Colore e forma:SolidPeso molecolare:306.32ZIKV-IN-3
CAS:ZIKV-IN-3, an andrographolide derivative, inhibits ZIKV NS5 MTase (IC50: 18.34 μM) and replication. Used for Zika virus research.Formula:C39H41NO4Colore e forma:SolidPeso molecolare:587.75JNJ-7925476 free base
CAS:JNJ-7925476 is an TRI antidepressant agent.Formula:C20H19NPurezza:98%Colore e forma:SolidPeso molecolare:273.37Y08175
CAS:Y08175, a CBP Bromodomain inhibitor, IC50: 37 nM (AlphaScreen), 178.15 nM (HTRF). Useful in prostate cancer research.Formula:C23H19FN4O5Colore e forma:SolidPeso molecolare:450.42J1075
CAS:<p>J1075 is an histone deacetylase 8 (HDAC8) inhibitor.</p>Formula:C9H6ClNO2SPurezza:98%Colore e forma:SolidPeso molecolare:227.67S-Aristeromycinylhomocysteine
CAS:S-Aristeromycinylhomocysteine is an inhibitor of adenosylmethionine decarboxylase.Formula:C15H22N6O4SColore e forma:SolidPeso molecolare:382.44(R)-OR-S1
CAS:(R)-OR-S1 is a SAM-competitive, highly selective, orally bioavailable dual inhibitor of EZH1/2.Formula:C26H34BrN3O4Purezza:98%Colore e forma:SolidPeso molecolare:532.47JNJ-9350
CAS:JNJ-9350: SMOX inhibitor (IC50 0.01 μM), PAO inhibitor (IC50 0.79 μM), for cancer research.Formula:C25H22N6OColore e forma:SolidPeso molecolare:422.48HDAC-IN-28
CAS:<p>HDAC-IN-28 is a novel inhibitor of HDAC that significantly inhibits tumour growth and metastasis.</p>Formula:C23H26N4O4SColore e forma:SolidPeso molecolare:454.54ZLD10A
CAS:ZLD10A is a highly potent and selective small molecule inhibitor of EZH2.Formula:C37H48N4O4Purezza:98%Colore e forma:SolidPeso molecolare:612.8WAY-260022
CAS:WAY-260022 is the norepinephrine transporter inhibitor.Formula:C21H31F3N2O2Purezza:97.61% - 99.41%Colore e forma:SolidPeso molecolare:400.48HPB
CAS:HPB is a selective HDAC6 deacetylase inhibitorFormula:C18H20N2O4Colore e forma:SolidPeso molecolare:328.36MC4343
MC4343, a potent dual inhibitor targeting both EZH2 and histone deacetylase, presents promising potential for cancer research applications.Formula:C36H41N5O4Colore e forma:SolidPeso molecolare:607.74PKN1/2-IN-1
CAS:PKN1/2-IN-1 is a potent and selective PKN2 inhibitor, membrane permeability and anticancer.Protein kinase N proteins (PKN) are effectors of Rho GTPases.Formula:C14H15N3OPurezza:99.72%Colore e forma:SolidPeso molecolare:241.29Ref: TM-T60339
2mg144,00€5mg235,00€10mg376,00€25mg747,00€50mg1.121,00€100mg1.768,00€1mL*10mM (DMSO)259,00€TK4b
CAS:TK4b, a JAK inhibitor, targets leukemia/lymphoid diseases, with IC50s: 18.42 nM (JAK3) & 19.40 nM (JAK2).Formula:C21H22N2O2Colore e forma:SolidPeso molecolare:334.41CBB1003
CAS:CBB1003 is a new inhibitor of histone demethylase LSD1 (IC50: 10.54 μM).Formula:C25H31N9O4Purezza:98%Colore e forma:SolidPeso molecolare:521.57CYP51/HDAC-IN-1
CAS:Orally active CYP51/HDAC-IN-1 dual inhibitor targets virulence factors and resistance genes; effective against Candidiasis and Cryptococcal meningitis.Formula:C30H40F2N6O4Colore e forma:SolidPeso molecolare:586.67MAT2A inhibitor 3
CAS:MAT2A inhibitor 3 can be used in the cancer research.Formula:C16H14ClN3OColore e forma:SolidPeso molecolare:299.75BPTF-IN-1
CAS:BPTF-IN-1 (AU1), a BPTF bromodomain inhibitor with 2.8 μM affinity, shows higher selectivity over BRD4 and possesses antimalarial properties.Formula:C23H23FN6O3Colore e forma:SolidPeso molecolare:450.47Cercosporamide
CAS:Cercosporamide is a ATP-competitive Pkc1 kinase inhibitor (IC50 <50 nM; Ki <7 nM). It also is a unique Mnk inhibitor.Formula:C16H13NO7Purezza:98%Colore e forma:SolidPeso molecolare:331.28NSD3-IN-1
CAS:NSD3-IN-1, a histone methyltransferase NSD3 inhibitor, demonstrates an IC50 of 28.58 μM.Formula:C13H13N5OSColore e forma:SolidPeso molecolare:287.34HDAC1-IN-4
CAS:HDAC1-IN-4 is a potent inhibitor of Plasmodium falciparum HDAC1 (PfHDAC1) with low cytotoxicity and antimalarial effects (IC50<5 nM).Formula:C21H24BrClN6O2Colore e forma:SolidPeso molecolare:507.82AMPK activator 6
CAS:AMPK activator 6 stimulates AMPK, lowers lipids in cells, and reduces serum TC, LDL-C, and TG. Useful for NAFLD and metabolic research.Formula:C25H28O5Colore e forma:SolidPeso molecolare:408.49HAT-IN-1
CAS:HAT-IN-1 is an inhibitor of HAT used in the research of cancer.Formula:C23H18BrF4N3O4Purezza:98%Colore e forma:SolidPeso molecolare:556.3HDAC6-IN-15
HDAC6-IN-15: selective HDAC6 inhibitor, IC50 of 38.2 nM, for cancer and neurodegenerative research.Formula:C25H28FFeN3O2Colore e forma:SolidPeso molecolare:477.35OUL245
CAS:OUL245: A selective PARP2 inhibitor (IC50=44nM), also inhibits other PARPs/TNKS (IC50=2.9-8.8μM).Formula:C8H5N3OSColore e forma:SolidPeso molecolare:191.21CTX-0124143
CAS:CTX-0124143 is a histone acetyltransferase inhibitor with an IC50 value of 1.0 μM for KAT6A.CTX-0124143 can be used to study cellular senescence.Formula:C17H13FN2O3SPurezza:98.24%Colore e forma:SolidPeso molecolare:344.36Ro 31-8830
CAS:Ro 31-8830, a derivative of Ro 31-8425, has in vivo anti-inflammatory activity.Formula:C28H28N4O2Purezza:98%Colore e forma:SolidPeso molecolare:452.55IHCH-3064
CAS:IHCH-3064: dual-action cancer immunotherapy, A2AR affinity (Ki 2.2 nM), selective HDAC1 inhibitor (IC50 80.2 nM).Formula:C25H21N9O2Colore e forma:SolidPeso molecolare:479.49JAK3i
CAS:<p>JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.</p>Formula:C18H15FN4O3Purezza:98.61% - 99.81%Colore e forma:SolidPeso molecolare:354.34SRI-42127
CAS:SRI-42127 is a novel small molecule inhibitor of the RNA regulatory factor HuR that inhibits tumor growth and reduces neuropathic pain following nerve injury.Formula:C19H20N6OPurezza:99.66%Colore e forma:SolidPeso molecolare:348.4HDAC6-IN-6
CAS:<p>HDAC6-IN-6: Potent HDAC6 blocker, BBB-permeable, IC50: 0.025μM; inhibits AChE, Aβ 1-42 aggregation; promotes neurite growth, low neurotoxicity.</p>Formula:C20H15N3O2Colore e forma:SolidPeso molecolare:329.35S2101
CAS:S2101 is a specific LSD1 histone demethylase inhibitor with an IC50 of 0.99 μM and a Ki of 0.61 μM, suitable for research into cancer and viral infections.Formula:C16H16ClF2NOPurezza:98%Colore e forma:SolidPeso molecolare:311.75LEM-14-1189
CAS:LEM-14-1189 inhibits NSD1/2/3 (IC50: 418/111/60 μM), targets nuclear receptors, and may treat cancer and blood diseases.Formula:C35H34N6O5S2Purezza:98.06%Colore e forma:SolidPeso molecolare:682.81BRD4-BD1-IN-2
CAS:<p>BRD4-BD1-IN-2: Potent, selective BRD4-BD1 inhibitor, IC50=2.51µM; 20x less active on BD2; for cardiovascular/cancer research.</p>Formula:C20H15Br3N4O2Purezza:99.39%Colore e forma:SolidPeso molecolare:583.07BiBET
CAS:BiBET is a potent, selective, bivalent inhibitor of BET bromodomains.Formula:C26H30N10O3Colore e forma:SolidPeso molecolare:530.58KF 13218
CAS:KF 13218 is a selective, potent and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.Formula:C20H20N2O3Purezza:98%Colore e forma:SolidPeso molecolare:336.38SIRT5 inhibitor 2
CAS:SIRT5 inhibitor 2 (compound 49) has inhibitory activity through SIRT5-dependent deacetylation and cancer and neurodegenerative diseases.Formula:C18H12Cl2N2O3SPurezza:99.38% - 99.87%Colore e forma:SolidPeso molecolare:407.27Y06036
CAS:Y06036, a potent and selective BET inhibitor, can bind to the BRD4(1) bromodomain (Kd: 82 nM).Formula:C16H15BrN2O5SPurezza:99.97%Colore e forma:SolidPeso molecolare:427.27Furamidine
CAS:Furamidine is a PRMT1-selective, cell-permeable inhibitor (IC50: 9.4μM), also targeting TDP-1, and is an antiparasitic bisbenzamidine derivative.Formula:C18H16N4OPurezza:98%Colore e forma:SolidPeso molecolare:304.35SHP2/HDAC-IN-1
CAS:SHP2/HDAC-IN-1: dual SHP2/HDAC inhibitor, IC50: 20.4 nM/25.3 nM, boosts antitumor immunity, aids cancer immunotherapy research.Formula:C34H35Cl2N7O3Colore e forma:SolidPeso molecolare:660.59JFD00244
CAS:JFD00244 is an inhibitor of sirtuin 2 (SIRT2). It has an anti-tumor effect.Formula:C30H26N2O4Purezza:98%Colore e forma:SolidPeso molecolare:478.54Aurora A/PKC-IN-1
CAS:Aurora A/PKC-IN-1 inhibits AurA (IC50: 6.9 nM), PKCα (IC50: 16.9 nM), and hinders breast cancer cell growth and spread.Formula:C16H14N6OSe2Colore e forma:SolidPeso molecolare:464.24BI-9321
CAS:BI-9321: Selective NSD3-PWWP1 antagonist, Kd 166 nM. Inactive against NSD2-PWWP1/NSD3-PWWP2.Formula:C22H21FN4Purezza:98%Colore e forma:SolidPeso molecolare:360.43JAK-2/3-IN-2
CAS:JAK-2/3-IN-2 (Compound 3h) is a potent JAK2 & JAK3 inhibitor with IC50s of 23.85 nM (JAK2) & 18.9 nM (JAK3).Formula:C19H19ClN2OSColore e forma:SolidPeso molecolare:358.89AMPK activator 12
CAS:AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level of GDF15 protein for cancer research.Formula:C23H24BrNO2Purezza:99.55%Colore e forma:SolidPeso molecolare:426.35HDAC6-IN-11
CAS:HDAC6-IN-11 (Compound 9) is a cancer cell growth blocker, selectively inhibiting HDAC6 (>300-fold) with an IC50 of 20.7 nM.Formula:C19H16N2O4Colore e forma:SolidPeso molecolare:336.34LSD1-IN-13
CAS:LSD1-IN-13, an oral LSD1 blocker (IC50: 24.43 nM), boosts CD86 (EC50: 470 nM), and triggers AML cell line differentiation.Formula:C23H29N3O2SColore e forma:SolidPeso molecolare:411.56BET-IN-7
CAS:BET-IN-7 is a potent BET inhibitor with a Ki of 12.27 μM and Kd of 89.3 μM, useful in sepsis research.Formula:C18H12ClN3OSColore e forma:SolidPeso molecolare:353.83Aurora kinase inhibitor-9
CAS:Aurora kinase inhibitor-9 (9d) targets AURKA/B with IC50: 0.093 μM for A and 0.09 μM for B, with wide anti-proliferative effects.Formula:C19H17Cl2N3O4SColore e forma:SolidPeso molecolare:454.33TAK-418
CAS:TAK-418 is an orally active LSD1/KDM1A inhibitor with a 2.9 nM IC50, potential for autism therapy.Formula:C17H25ClN2O2SPurezza:99.69%Colore e forma:SolidPeso molecolare:356.91Ref: TM-T39252
1mg138,00€5mg329,00€10mg520,00€25mg1.064,00€50mg1.434,00€100mg1.920,00€200mg2.593,00€1mL*10mM (DMSO)386,00€HDAC1/MAO-B-IN-1
CAS:HDAC1/MAO-B-IN-1 is a selective Alzheimer’s research inhibitor with IC50s: HDAC1 (21.4 nM) & MAO-B (99 nM); crosses the blood-brain barrier.Formula:C18H17ClN2O2Colore e forma:SolidPeso molecolare:328.79A2B57
CAS:A2B57 is a selective SIRT2 inhibitor.Formula:C22H19N5OPurezza:98%Colore e forma:SolidPeso molecolare:369.42Furamidine dihydrochloride
CAS:Furamidine dihydrochloride is a cell-permeable, selective PRMT1 inhibitor that also binds AT-rich DNA. It blocks proliferation in leukemia cell lines.Formula:C18H18Cl2N4OPurezza:98.16%Colore e forma:SolidPeso molecolare:377.27JAK3-IN-12
CAS:JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.Formula:C19H19N5O4SColore e forma:SolidPeso molecolare:413.45PARP11 inhibitor ITK7
CAS:ITK7 is a potent, selective PARP11 inhibitor with an IC50 of 14 nM, useful for cellular localization research.Formula:C17H14N4OSColore e forma:SolidPeso molecolare:322.38HDAC-IN-41
CAS:HDAC-IN-41 is a selective class I HDAC inhibiting HDAC1, 2, & 3 with IC50: 0.62-1.46 µM; oral use; has NO-release.Formula:C20H22N4O6SColore e forma:SolidPeso molecolare:446.48CTPB
CAS:CTPB is a potent p300 histone acetyltransferase (HAT) activator that can be used in the preparation of hair growth promoters and/or hair loss treatments.Formula:C31H43ClF3NO2Purezza:99.51%Colore e forma:SolidPeso molecolare:554.13A2AAR/HDAC-IN-1
CAS:A2AAR/HDAC-IN-1 (compound 14c) is an orally active, balanced A2AAR/HDAC dual inhibitor of A2AAR (Ki: 163.5 nM), HDAC1 (IC50: 145.3 nM). effect.Formula:C24H21N7O2Colore e forma:SolidPeso molecolare:439.47MARK-IN-4
CAS:MARK-IN-4 inhibits microtubule kinase (MARK) effectively (IC50: 1 nM), a target for Alzheimer's therapy.Formula:C21H23N7OSColore e forma:SolidPeso molecolare:421.52BI-831266
CAS:BI-831266 is a potent and selective Aurora kinase B inhibitor.Formula:C27H38ClN7O2Colore e forma:SolidPeso molecolare:528.09INO-1001 methanesulfonate
CAS:INO-1001 methanesulfonate is a strong PARP inhibitor with chemosensitization and radiosensitization effects.Formula:C24H29N3O7S2Colore e forma:SolidPeso molecolare:535.63PARP1-IN-9
CAS:PARP1-IN-9, potent PARP1 inhibitor with 30.51 nM IC50, outperforms Olaparib in anticancer efficacy.Formula:C18H21N3O5Colore e forma:SolidPeso molecolare:359.38HDAC6-IN-14
HDAC6-IN-14, an inhibitor of HDAC6 (HDAC), exhibits high selectivity with an IC50 value of 42 nM, demonstrating over 100-fold selectivity compared to HDAC1,Formula:C24H30FN3O4Colore e forma:SolidPeso molecolare:443.51TUL01101
CAS:TUL01101, a selective oral JAK1 inhibitor (IC50: 3 nM), also targets JAK2, JAK3, TYK2; for rheumatoid arthritis research.Formula:C22H25F2N5O2Colore e forma:SolidPeso molecolare:429.46NCDM-32B
CAS:NCDM-32B, a novel potent and selective KDM4 inhibitor, impairs viability and transforms phenotypes of basal breast cancer.Formula:C15H30N2O4Purezza:98%Colore e forma:SolidPeso molecolare:302.41(R)-BAY1238097
CAS:(R)-BAY1238097 is a selective inhibitor against the binding of BET proteins to histones, used in acute myeloid leukemia (AML) and multiple myeloma (MM) studies.Formula:C25H33N5O3Purezza:98.77%Colore e forma:SolidPeso molecolare:451.56Ref: TM-T13442
1mg51,00€5mg106,00€10mg175,00€25mg375,00€50mg655,00€100mg1.103,00€200mg1.483,00€1mL*10mM (DMSO)119,00€D 595
CAS:D595 is a phenethylamine-type calcium channel blocker. The most potent phenylethylamine with respect to negative inotropy was D595 (EC50: 794 nmol/l).Formula:C25H32Cl2N2O2Purezza:98%Colore e forma:SolidPeso molecolare:463.44HDAC8/BRPF1-IN-1
CAS:Compound 23a, dual HDAC8/BRPF1 inhibitor: IC50 HDAC8 = 443 nM, Kd BRPF1 = 67 nM; weak against HDAC1/6.Formula:C19H19N3O6SColore e forma:SolidPeso molecolare:417.44RSC-133
CAS:promotes the reprogramming of human somatic cells to pluripotent stem cellsFormula:C18H15N3O2Purezza:98%Colore e forma:SolidPeso molecolare:305.33J1038
CAS:J1038 is a novel Histone Deacetylase 8 (HDAC8) Inhibitor .Formula:C10H10N2O3SColore e forma:SolidPeso molecolare:238.26DFPM
CAS:DFPM activates plant resistance, inhibits root growth, reduces Col-0 root cell viability, and is light-sensitive in water.Formula:C16H15Cl2NOSColore e forma:SolidPeso molecolare:340.27MAT2A-IN-6
CAS:MAT2A-IN-6 inhibits MAT2A, may slow MTAP-deficient cancer cell growth, has research value in cancer.Formula:C18H13ClF3N3O3Colore e forma:SolidPeso molecolare:411.76Metformin icosapent
CAS:Metformin icosapent activates AMPK, enhancing insulin sensitivity and reducing glucose absorption for better glycemic control.Formula:C24H41N5O2Colore e forma:SolidPeso molecolare:431.62KD 5170
CAS:KD 5170, a pan inhibitor of histone deacetylases (HDACs), demonstrates widespread antitumor activity both in vitro and in vivo [1].Formula:C20H25N3O5S2Colore e forma:SolidPeso molecolare:451.56MZ-242
CAS:MZ-242 is an effective and selective inhibitor of Sirt2.Formula:C24H27N7O3S2Purezza:98%Colore e forma:SolidPeso molecolare:525.65KDOAM-25
CAS:KDOAM-25, a potent KDM5 inhibitor, enhances H3K4 methylation, hampers MM1S cell growth; IC50: 71 nM (5A), 19 nM (5B), 69 nM (5C/D).Formula:C15H25N5O2Purezza:98%Colore e forma:SolidPeso molecolare:307.39UL04
CAS:UL04 is an inhibitor of CREBBP bromodomain.Formula:C18H17NO5Colore e forma:SolidPeso molecolare:327.33BRD4 Inhibitor-25
BRD4 Inhibitor-25 blocks BRD4 (BD1: IC50 0.82 μM, BD2: 1.94 μM), induces cell death in ovarian cancer, used in cancer research.Formula:C29H27N5O6SColore e forma:SolidPeso molecolare:573.62PRMT5-IN-2
CAS:PRMT5-IN-2 is an inhibitor of protein arginine methyltransferase 5.Formula:C17H16ClFN4O4Purezza:98%Colore e forma:SolidPeso molecolare:394.781,2-Didecanoylglycerol
CAS:1,2-Didecanoylglycerol has functions as bioregulator of protein kinase C in human platelets.Formula:C23H44O5Colore e forma:SolidPeso molecolare:400.59CAY10685
CAS:CAY10685, a CPTH2 analog with an alkyne for click reactions, inhibits NAT10 to study cancer-related chromatin changes.Formula:C17H16ClN3SColore e forma:SolidPeso molecolare:329.85DNMT3A-IN-1
CAS:DNMT3A-IN-1 is a potent, selective DNMT3A inhibitor with KI 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC).Formula:C30H38N6O4Colore e forma:SolidPeso molecolare:546.66AChE/HDAC-IN-1
CAS:COX-2-IN-23 (A10) inhibits AChE & HDAC (IC50s: 0.12 & 0.23 nM), has antioxidant/metal-binding traits, and is used in Alzheimer's research.Formula:C26H27ClN4O3Colore e forma:SolidPeso molecolare:478.97Aurora Kinases-IN-2
CAS:Aurora Kinases-IN-2 (12Aj) hinders Aurora A/B kinases (IC50: 90/152 nM), used in cancer studies.Formula:C22H18ClN5O3Colore e forma:SolidPeso molecolare:435.86TYK2-IN-11
CAS:TYK2-IN-11 (5B) selectively inhibits TYK2 (IC50: 0.016 nM) and JAK1 (IC50: 0.31 nM), aiding autoimmune and inflammatory disease research.Formula:C18H17N5O3SColore e forma:SolidPeso molecolare:383.42F-amidine
CAS:F-amidine is a bioavailable irreversible PAD4 inactivator.Formula:C14H19FN4O2Colore e forma:SolidPeso molecolare:294.32CypD inhibitor C-9
CAS:<p>CypD inhibitor C-9 is a CypD inhibitor, it attenuates mitochondrial and cellular perturbation insulted by Aß and calcium stress.</p>Formula:C22H22N4O4S2Colore e forma:SolidPeso molecolare:470.564-iodo-SAHA
CAS:4-Iodo-SAHA (1k), an oral HDAC inhibitor for cancer research, has EC50s from 0.12 to 1.3 μM across various cell lines.Formula:C14H19IN2O3Colore e forma:SolidPeso molecolare:390.22JAK-IN-20
CAS:JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.Formula:C28H30FN7O2Colore e forma:SolidPeso molecolare:515.58UNC0379 TFA
CAS:UNC0379 TFA inhibits SETD8 (IC50: 7.3 μM), selective for 15+ methyltransferases.Formula:C25H36F3N5O4Colore e forma:SolidPeso molecolare:527.589Peficitinib hydrochloride
CAS:Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).Formula:C18H23ClN4O2Colore e forma:SolidPeso molecolare:362.86
