Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2442 prodotti di "Cromatina/Epigenetica"
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103D5R
CAS:103D5R selectively inhibits hif-1α, reducing its levels in hypoxia or with cobalt ions, dose- and time-dependently.Formula:C20H21N3O2Colore e forma:SolidPeso molecolare:335.4Antiproliferative agent-17
CAS:Antiproliferative Agent-17 exhibits both antimicrobial properties against Gram-positive bacteria and anticancer activity [1].Formula:C26H28N2OSColore e forma:SolidPeso molecolare:416.58Sirt2-IN-6
CAS:Sirt2-IN-6 is a potent and selective inhibitor of SIRT2 (IC50: 0.815 μM) and can be used to study cancer.Formula:C26H26N6O3SColore e forma:SolidPeso molecolare:502.59ZYJ-25e
CAS:ZYJ-25e is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities.Formula:C30H40N4O8Purezza:98%Colore e forma:SolidPeso molecolare:584.66AA-CW236
CAS:AA-CW236 is a covalent inhibitor of human O(6)-alkylguanine DNA methyltransferase (MGMT).Formula:C17H16ClF3N4O2Colore e forma:SolidPeso molecolare:400.78NN-390
CAS:NN-390: selective HDAC6 inhibitor, IC50 9.8 μM, blood-brain barrier penetrant, potential for metastatic group 3 neural tube cancer research.Formula:C17H16F4N2O4SColore e forma:SolidPeso molecolare:420.38SPV106
CAS:SPV106 is a ligand of lysine acetyltransferases (KATs).Formula:C22H40O4Purezza:98%Colore e forma:SolidPeso molecolare:368.55EZH2-IN-9
CAS:EZH2-IN-9 inhibits EZH2, targeting SET mutations linked to cancer by reducing H3K27me3 levels.Formula:C28H32ClF2N3O5SColore e forma:SolidPeso molecolare:596.09HDAC/CK2-IN-1
CAS:HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.Formula:C15H18Br4N4O2Colore e forma:SolidPeso molecolare:605.95HDAC-IN-30
CAS:<p>HDAC-IN-30 is a potent HDAC inhibitor targeting HDAC1, 2, 3, 6, and 8 with strong antitumor efficacy.</p>Formula:C22H23N5O3Colore e forma:SolidPeso molecolare:405.45BIX-01338 hydrate
CAS:BIX-01338 hydrate is an inhibitor of histone lysine methyltransferase.Formula:C32H26F3N3O7Purezza:98%Colore e forma:SolidPeso molecolare:621.56AMPK activator 4
CAS:Potent, selective AMPK activator 4 enhances glucose tolerance and insulin sensitivity without affecting mitochondrial complex I.Formula:C24H21ClN2O3Purezza:99.97% - 99.99%Colore e forma:SolidPeso molecolare:420.89Ref: TM-T62238
1mg90,00€5mg183,00€10mg354,00€25mg595,00€50mg847,00€100mg1.159,00€500mg2.308,00€1mL*10mM (DMSO)215,00€Bromodomain inhibitor-9
CAS:Bromodomain inhibitor-9 selectively targets BRD4-1 (Kd 12 nM), used in metabolic, inflammatory, fibrotic, and autoimmune disease studies.Formula:C24H28N4O5SColore e forma:SolidPeso molecolare:484.57EZH2-IN-11
CAS:EZH2-IN-11, a potent E2HZ inhibitor with potential for cancer treatment, is highlighted in patent WO2019204490A1.Formula:C28H36ClN3O5SColore e forma:SolidPeso molecolare:562.12HDAC3 Inhibitor
CAS:HDAC3 inhibitor: allosteric, Ki=0.16 nM, favors HDAC3 over HDAC1/2, targets specific leukemia cells, EC50=36.37-151.7 nM.Formula:C20H23N3O2Colore e forma:SolidPeso molecolare:337.42DC-BPi-11
CAS:DC-BPi-11 inhibits BPTF at IC50 698 nM and significantly reduces leukemia cell growth.Formula:C20H23N5O2SColore e forma:SolidPeso molecolare:397.49DDO-2093 dihydrochloride
DDO-2093 dihydrochloride: potent MLL1-WDR5 inhibitor, IC50=8.6 nM, Kd=11.6 nM, antitumor.Formula:C29H39Cl3FN9O3Colore e forma:SolidPeso molecolare:687.04Dot1L-IN-2
CAS:Dot1l-in-2 is an effective, selective and oral bioutilization inhibitor of histone methyltransferase Dot1L, with IC50 and Ki of 0.4 nM and 0.08 nM, respectivelyFormula:C27H24N8OPurezza:98%Colore e forma:SolidPeso molecolare:476.53MC-1353
CAS:MC-1353 is a potent, selective inhibitor of HDAC class I.Formula:C16H16N2O3Colore e forma:SolidPeso molecolare:284.31CPI-455 HCl
CAS:CPI-455: specific KDM5A inhibitor, IC50=10±1nM, increases H3K4me3, reduces DTPs in cancer cells.Formula:C16H15ClN4OPurezza:98%Colore e forma:SolidPeso molecolare:314.77OTS186935
CAS:OTS186935 is a inhibitor of protein methyltransferase SUV39H2(IC50 of 6.49 nM).Formula:C25H26ClN5O2Purezza:98%Colore e forma:SolidPeso molecolare:463.96PARP-2/1-IN-2
CAS:PARP-2/1-IN-2, Veliparib's enantiomer, inhibits PARP-1/2 (Ki: 5/2 nM) with 3 nM EC50 in cell assay.Formula:C13H16N4OColore e forma:SolidPeso molecolare:244.29Tripartin
CAS:Tripartin specifically inhibits the histone H3 lysine 9 demethylase KDM4 in HeLa cells.Formula:C10H8Cl2O4Colore e forma:SolidPeso molecolare:263.07PBRM1-BD2-IN-1
CAS:PBRM1-BD2-IN-1: Selective PBRM1 inhibitor with Kd 0.7μM, IC50 0.2μM, useful in cancer research.Formula:C17H19ClN2OColore e forma:SolidPeso molecolare:302.8MI-2-2
CAS:MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.Formula:C17H20F3N5S2Purezza:99.65%Colore e forma:SolidPeso molecolare:415.5BAY-598 R-isomer
CAS:BAY-598 R-isomer, a SMYD2-selective inhibitor, is the R-enantiomer of BAY589, not targeting PAR1.Formula:C22H20Cl2F2N6O3Colore e forma:SolidPeso molecolare:525.34PRMT5-IN-C17
CAS:PRMT5-IN-C17 is a novel potent, selective, and cell active protein arginine methyltransferase 5 (PRMT5) inhibitor.Formula:C18H17N3O4SColore e forma:SolidPeso molecolare:371.415WKS
CAS:5WKS, or ZINC97756584, is a G9a inhibitor targeting H3K9me2 for gene silencing research in autoimmune diseases and tumors.Formula:C24H36ClN5O2Purezza:98%Colore e forma:SolidPeso molecolare:462.03ZL0454
CAS:ZL0454 is an effective and selective Bromodomain-containing protein 4 inhibitors (IC50: 49 and 32 nM for BD1 and BD2).Formula:C18H22N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:374.46PIM1-IN-7
CAS:PIM1-IN-7 inhibits PIM-1 (IC50: 0.67μM), toxic to HCT-116/MCF-7 cells (IC50: 42.9/7.68μM).Formula:C23H23N5OColore e forma:SolidPeso molecolare:385.46CL67
CAS:CL67 is a hypoxia-inducible factor pathway inhibitor. It acts by binding to a G-quadruplex higher-order structure in the HIF promoter sequence in vitro.Formula:C38H42N10O2Colore e forma:SolidPeso molecolare:670.81BRD4-BD1/2-IN-1
CAS:BRD4-BD1/2-IN-1 efficiently blocks BRD4 BD-1/2 under 100 nM IC50 (US20150148375A1, cmpd 5).Formula:C21H14F2N4O2Colore e forma:SolidPeso molecolare:392.36PDAT
CAS:PDAT is a noncompetitive Indolethylamine N-methyltransferase inhibitor.Formula:C15H23N3Purezza:98%Colore e forma:SolidPeso molecolare:245.36TM6008
CAS:TM6008 is an inhibitor of prolyl hydroxylase that protects against cell death after hypoxia.Formula:C21H17N5O3Purezza:98%Colore e forma:SolidPeso molecolare:387.39UNC6212 (Kme2)
UNC6212 (Kme2), a dimethyllysine (Kme2)-containing ligand, has a K D for CBX5 of 5.7 μM .Formula:C39H53N7O11Colore e forma:SolidPeso molecolare:795.88SKF 91488 dihydrochloride
CAS:histamine N-methyltransferase inhibitorFormula:C7H19Cl2N3SPurezza:98%Colore e forma:SolidPeso molecolare:248.22aPKC-I
CAS:aPKC-I specifically inhibits PKCζ/i, blocks VEGF effects, and prevents IR-induced permeability in cells and live models.Formula:C15H17NO4SColore e forma:SolidPeso molecolare:307.36AMPK activator 9
CAS:AMPK activator 9 (ZM-6) is a potent α2β1γ1 agonist with an EC50 of 1.1 µM, potential for type 2 diabetes research.Formula:C31H28F4N4O4Colore e forma:SolidPeso molecolare:596.57NAT2-IN-1
CAS:NAT2-IN-1 (APA) is a selective inhibitor of the drug metabolism enzyme N-acetyltransferase 2 (NAT2), capable of targeting and eliminating cells with slow NAT2Formula:C19H20N4O3Colore e forma:SolidPeso molecolare:352.39SC-10
CAS:SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.Formula:C17H22ClNO2SPurezza:99.24% - 99.58%Colore e forma:SolidPeso molecolare:339.88VE-465
CAS:VE-465 is an inhibitor of Aurora kinase, which involves in multiple mitotic events.Formula:C22H28N8OSColore e forma:SolidPeso molecolare:452.58Tinostamustine HCl
CAS:Tinostamustine (EDO-S101) is an alkylating HDACi fusion molecule, enhancing potency and overcoming drug resistance.Formula:C19H29Cl3N4O2Colore e forma:SolidPeso molecolare:451.82FAK/aurora kinase-IN-1
CAS:FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].Formula:C23H24ClN7O3Colore e forma:SolidPeso molecolare:481.93CPI-4203
CAS:CPI-4203 is a selective inhibitor of KDM5 demethylases.Formula:C16H14N4OColore e forma:SolidPeso molecolare:278.31PRMT5-IN-17
CAS:PRMT5-IN-17 is a PRMT5-blocking compound with anticancer properties, linked to epigenetic changes.Formula:C26H33N7O2Colore e forma:SolidPeso molecolare:475.59IACS-9571 hydrochloride
CAS:IACS-9571 hydrochloride: potent TRIM24/BRPF1 inhibitor; IC50 = 8 nM (TRIM24); Kd = 31 nM (TRIM24), 14 nM (BRPF1).Formula:C32H43ClN4O8SColore e forma:SolidPeso molecolare:679.22KDM2B-IN-4
CAS:KDM2B-IN-4, from patent WO2016112284A1 as 182b, is a potent KDM2B inhibitor used in cancer research.Formula:C24H28N2O2Colore e forma:SolidPeso molecolare:376.49YM-53601
CAS:YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.Formula:C21H22ClFN2OPurezza:99.65%Colore e forma:SolidPeso molecolare:372.86CAY10721
CAS:CAY10721 inhibits SIRT3 (39% at 200 μM), linked to OSCC and breast cancer; lowers OSCC growth, enhances radio/chemo sensitivity.Formula:C18H13N3O3SColore e forma:SolidPeso molecolare:351.38Dihydro-5-azacytidine acetate
CAS:Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1Formula:C10H18N4O7Purezza:98%Colore e forma:SolidPeso molecolare:306.27CSV0C018875 Hydrochloride
CAS:CSV0C018875 Hydrochloride: Novel G9a inhibitor with low toxicity, effective in enzyme/cell assays, outperforms BIX-0129.Formula:C18H18Cl2N2OColore e forma:SolidPeso molecolare:349.255CAY10669
CAS:CAY10669 inhibits PCAF (IC50 = 662 μM), is twice as potent as anacardic acid, and reduces H4 acetylation in HepG2 cells at 30-60 μM.Formula:C20H22O4Colore e forma:SolidPeso molecolare:326.39BETi-211
CAS:BETi-211 is a selective inhibitor BET bromodomain.Formula:C26H29N7O3Colore e forma:SolidPeso molecolare:487.55IND 1316
CAS:IND 1316 is an activator of AMP-activated protein kinase (AMPK).Formula:C22H17NO3Colore e forma:SolidPeso molecolare:343.38Galegine hydrochloride
CAS:Galegine hydrochloride, from G. officinalis, leads to weight loss, activates AMPK in various cells, and has antibacterial properties.Formula:C6H14ClN3Colore e forma:SolidPeso molecolare:163.65I-BET151 dihydrochloride
CAS:I-BET 151 dihydrochloride is a BET bromodomain inhibitor that prevents BET from recruiting to chromatin.Formula:C23H23Cl2N5O3Purezza:98%Colore e forma:SolidPeso molecolare:488.37Vibsanin A
CAS:Vibsanin A, an activator of protein kinase C (PKC) and an inhibitor of HSP90, demonstrates anti-proliferative effects on human cancer cell lines.Formula:C25H38O4Colore e forma:SolidPeso molecolare:402.57Acefylline piperazine
CAS:Acefylline piperazine, a less toxic theophylline derivative, treats asthma and bronchitis by bronchodilation, stimulating respiration and CNS.Formula:C9H10N4O4·xC4H10N2Colore e forma:SolidPeso molecolare:562.54G9a-IN-2
CAS:G9a-IN-2 (Compound 7i) is an inhibitor of the histone methyltransferase G9a, with an IC50 of 0.024 μM. It can reduce the levels of H3K9me2 and induce the expression of γ-globin mRNA. G9a-IN-2 shows potential for improving Sickle Cell Disease (SCD).Formula:C30H42N4O4Colore e forma:SolidPeso molecolare:522.68SMTIN-T140
CAS:SMTIN-T140: strong TRAP1 inhibitor, IC50=1.646μM, anticancer; disrupts mitochondria, boosts ROS, activates AMPK, shrinks PC3 tumors, no in vivo toxicity.Formula:C36H34BrClFN5OPPurezza:98%Colore e forma:SolidPeso molecolare:718.02HMS607P03
CAS:HMS607P03 is an activator of SIRT1 which induces autophagic cell death via the AMPK-mTOR-ULK complex and induces mitophagy by the SIRT1-PINK1-Parkin pathway.Formula:C26H19ClN4O3S2Colore e forma:SolidPeso molecolare:535.04IACS-9571
CAS:IACS-9571 is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).Formula:C32H42N4O8SPurezza:98%Colore e forma:SolidPeso molecolare:642.76CSV0C018875
CAS:CSV0C018875 is a quinoline-based EHMT2/G9a inhibitor with lower cytotoxicity than BIX-01294 [1].Formula:C18H17ClN2OColore e forma:SolidPeso molecolare:312.79HDAC/NAMPT-IN-1
CAS:HDAC/NAMPT-IN-1 (compound 39h) simultaneously inhibits HDAC and NAMPT, exhibiting IC 50 values ranging from 0.72 to 37081 nM for HDAC and 1618 nM for NAMPT [1].Formula:C19H21N5O2Colore e forma:SolidPeso molecolare:351.4(2R,5S)-Ritlecitinib
CAS:(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective inhibitor of JAK3 with IC 50 of 144.8 nM[1].Formula:C15H19N5OColore e forma:SolidPeso molecolare:285.34MI-3
CAS:MI-3 (Menin-MLL Inhibitor) (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).Formula:C18H25N5S2Purezza:98.66% - 99.61%Colore e forma:SolidPeso molecolare:375.55Povorcitinib
CAS:Povorcitinib is a highly potent and selective JAK1 inhibitor with significant potential for the investigation of cutaneous lupus erythematosus (CLE) and Lichen planus (LP).Formula:C23H22F5N7OColore e forma:SolidPeso molecolare:507.469SRTCX1003
CAS:SRTCX1003, a SIRT1 activator, suppresses inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity.Formula:C23H23N5O3SColore e forma:SolidPeso molecolare:449.53HDAC6-IN-5
CAS:HDAC6-IN-5 (11b), potent HDAC6 blocker, crosses BBB, IC50: 0.025μM, hinders Aβ1-42/AChE aggregation, boosts neurites, low toxicity.Formula:C20H14BrN3O2Colore e forma:SolidPeso molecolare:408.255-Octyl-α-ketoglutarate
CAS:In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes.Formula:C13H22O5Colore e forma:SolidPeso molecolare:258.31AMPK activator 1
CAS:AMPK activator 1 is an AMPK activator(compound No.1-75, EC50: <0.1μM).Formula:C32H33F3N4O3Purezza:98%Colore e forma:SolidPeso molecolare:578.62Aurora Kinases-IN-3
CAS:Aurora Kinases-IN-3 is an oral AURKB inhibitor that disrupts its mitotic localization, not its H3 Ser10 phosphorylation.Formula:C20H16F3N3O4Colore e forma:SolidPeso molecolare:419.355-Aza-4'-thio-2'-deoxycytidine
CAS:5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].Formula:C8H12N4O3SColore e forma:SolidPeso molecolare:244.27Bizine dihydrochloride
CAS:Bizine dihydrochloride is a potent LSD1 inhibitor in vitro, being selective versus monoamine oxidases A/B and the LSD1 homologue, LSD2.Formula:C18H25Cl2N3OColore e forma:SolidPeso molecolare:370.32(Rac)-BAY1238097
CAS:(Rac)-BAY1238097 is a inhibitor of BET(IC50 of 1.02 μM for BRD4),used in cancer research.Formula:C25H33N5O3Purezza:98%Colore e forma:SolidPeso molecolare:451.56BNS
CAS:BNS is a potent, prolyl-hydroxylase 2 (PHD2)-selective inhibitor.Formula:C18H16N2O6S2Purezza:98%Colore e forma:SolidPeso molecolare:420.46NR-160
CAS:NR-160 is a selective HDAC6 inhibitor (IC50=0.03μM), weaker on HDAC1-4,8, toxic to 7 cancer lines, boosts bortezomib and anthracycline effects.Formula:C25H21F3N6O3Colore e forma:SolidPeso molecolare:510.47EZH2-IN-7
CAS:EZH2-IN-7 inhibits EZH2, reducing H3K27me3 and tumor growth (e.g., breast, prostate cancer, leukemia). Potential in cancer research.Formula:C31H37D2N5O3SColore e forma:SolidPeso molecolare:563.75NCD38
CAS:NCD38 is a potent, selective LSD1 inhibitor.Formula:C37H37ClF3N3O4Purezza:98.21% - 98.86%Colore e forma:SolidPeso molecolare:680.16GNE-272
CAS:GNE-272 is a selective inhibitor of CBP/EP300 (IC50: 0.02, 0.03, and 13 μM for CBP, EP300, and BRD4, respectively) and a selective in vivo probe for CBP/EP300.Formula:C22H25FN6O2Colore e forma:SolidPeso molecolare:424.47HDAC ligand-1
CAS:HDAC ligand-1 is a synthetic precursor utilized in the production of PROTAC-based HDAC degraders [1].Formula:C7H8N2OPurezza:98%Colore e forma:SolidPeso molecolare:136.15SIRT2-IN-11
CAS:SIRT2-IN-11 (AEM1), a SIRT2 inhibitor (IC50 18.5μM), induces apoptosis and affects p53, used in cancer research.Formula:C21H22N2OColore e forma:SolidPeso molecolare:318.41PRMT5:MEP50 PPI
PRMT5:MEP50 PPI inhibitor with anti-tumor and anti-proliferative effects on lung and prostate cancers.Formula:C24H22N4O4Colore e forma:SolidPeso molecolare:430.46PBRM1-BD2-IN-6
CAS:PBRM1-BD2-IN-6: potent PBRM1 inhibitor with 0.22 µM IC50, anti-cancer research potential.Formula:C16H15ClN2OColore e forma:SolidPeso molecolare:286.76JAK-IN-11
CAS:JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.Formula:C23H22FN5O4SPurezza:99.75%Colore e forma:SolidPeso molecolare:483.52NV03
CAS:NV03 is a selective antagonist of the UHRF1-H3K9me3 interaction (Kd=2.4 μM) for cancer research. a ligand for E3 ligases in PROTAC synthesis.Formula:C19H27N5O2SPurezza:99.88%Colore e forma:SolidPeso molecolare:389.52M122
CAS:M122 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.Formula:C24H25N5OS2Colore e forma:SolidPeso molecolare:463.62HIF-1/2α-IN-2
CAS:HIF-1/2α-IN-2 is a potent inhibitor of HIF-1/2α, which effectively reduces the levels of HIF-1/2α.Formula:C16H11FN4O2SColore e forma:SolidPeso molecolare:342.35CAY10727
CAS:CAY10727 selectively inhibits PAD3 (15,600 M^-1min^-1) over PAD1, PAD2, and PAD4.Formula:C21H22Cl2N4O2Colore e forma:SolidPeso molecolare:433.33FNDR-20123 free base
CAS:FNDR-20123 is a safe, oral first-in-class anti-malarial HDAC inhibitor with low IC50s against Plasmodium and human HDACs.Formula:C21H23N5O2Colore e forma:SolidPeso molecolare:377.44CTK7A
CAS:CTK7A is a water-soluble inhibitor of p300. CTK7A inhibits tumor growth in xenografted mice.Formula:C28H24N2NaO6Purezza:98%Colore e forma:SolidPeso molecolare:507.498NL-103
CAS:NL-103, a dual-targeting compound, inhibits HDACs & Hh pathway, countering vismodegib-resistant Smo mutations.Formula:C26H27Cl2N5O4Colore e forma:SolidPeso molecolare:544.43Bromodomain inhibitor-10
CAS:Bromodomain inhibitor-10 (compound 128) suppresses BRD4-1/2 with Kd 15 nM/2.5 μM and curbs IL12p40 production.Formula:C20H20N4O3Colore e forma:SolidPeso molecolare:364.4EPZ033294
CAS:EPZ033294 has potential anticancer and antiproliferative activity.Formula:C20H22ClN7OPurezza:99.95%Colore e forma:SolidPeso molecolare:411.89SD-1029
CAS:SD-1029 is a JAK2 inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation and JAK-STAT signaling.Formula:C25H32Br2Cl2N2O3Colore e forma:SolidPeso molecolare:639.25HDAC6-IN-46
CAS:HDAC6-IN-46 (compound 12) is a selective inhibitor of histone deacetylase 6 (HDAC6), exhibiting an IC50 of 6.2 nM. It is utilized in research related to Alzheimer's disease.Formula:C26H21N3O4Colore e forma:SolidPeso molecolare:439.46Jaspamycin
CAS:Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα.Formula:C12H12N4O5Colore e forma:SolidPeso molecolare:292.25MAT2A inhibitor 1
CAS:MAT2A inhibitor 1 is an inhibitor of methionine adenosyltransferase 2A (MATA2) (IC50 < l00 nM).Formula:C31H22N6OSColore e forma:SolidPeso molecolare:526.61UMB-32
CAS:UMB-32: Potent, selective BRD4 inhibitor, Kd 550 nM, IC50 637 nM, also targets TAF1.Formula:C21H23N5OColore e forma:SolidPeso molecolare:361.44JJO-1
CAS:JJO-1 is a bi-quinoline activating all AMPK αβγ isoforms except γ3; it requires low ATP and is unaffected by γ mutations or β deletions.Formula:C19H13N3Colore e forma:SolidPeso molecolare:283.33
