Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2486 prodotti di "Cromatina/Epigenetica"
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JAK-IN-4
CAS:JAK-IN-4 is a prodrug of a JAK inhibitor, effective in murine collagen induced arthritis model.Formula:C18H21N4Na2O6PPurezza:98%Colore e forma:SolidPeso molecolare:466.341Sirt2-IN-5
CAS:Sirt2-IN-5 is a potent inhibitor of SIRT2.Formula:C26H27Cl2N5O3Colore e forma:SolidPeso molecolare:528.43CLB-016
CAS:CLB-016 is an inhibitor of hypoxia-inducible factor (HIF)-1.Formula:C17H20N6O3Purezza:98%Colore e forma:SolidPeso molecolare:356.38KAT modulator-1
CAS:KAT modulator-1 (Compound 3), an epigenetics research tool, selectively interacts with the full-length p300 protein but not its catalytic domain [1].Formula:C20H36O2Purezza:98%Colore e forma:SolidPeso molecolare:308.5Antitumor agent-101
CAS:Antitumor agent-101 is a selective, covalent inhibitor targeting lysine methyltransferases G9a/GLP, demonstrating IC50 values of 8.5 nM for G9a and 5.5 nM forFormula:C26H38N6O3Purezza:98%Colore e forma:SolidPeso molecolare:482.62CBP/p300-IN-19 hydrochloride
CAS:CBP/p300-IN-19 HCl is a p300/CBP HAT inhibitor (IC50: p300 1.4 μM, CBP 2.2 μM) with antitumor properties.Formula:C30H28ClN3O3Colore e forma:SolidPeso molecolare:514.02SJ1461
CAS:SJ1461 is a potent, orally active inhibitor of the BET family, selectively targeting and inhibiting BRD2 (BD1), BRD2 (BD2), BRD4 (BD1), and BRD4 (BD2) withFormula:C21H18ClN7OS2Purezza:98%Colore e forma:SolidPeso molecolare:484HSP70/SIRT2-IN-2
CAS:<p>HSP70/SIRT2-IN-2 (Compounds 1a), a dual inhibitor of SIRT2 and HSP70, exhibits an IC50 of 45.1±5.0 μM against SIRT2 and demonstrates antitumor activity [1].</p>Formula:C17H13N3S3Purezza:98%Colore e forma:SolidPeso molecolare:355.5A1B11
CAS:A1B11 is a selective SIRT2 inhibitor.Formula:C22H25N5OColore e forma:SolidPeso molecolare:375.47AMPK activator 7
CAS:<p>AMPK activator 7 (I-3-24, EC50: 8.8 nM) targets AMPK-related disorders like type 2 diabetes and obesity.</p>Formula:C23H22F3N3O5Colore e forma:SolidPeso molecolare:477.43PF-06679142
CAS:PF-06679142 is an effective AMPK activator. PF-06679142 exhibited robust activation of AMPK in rat kidneys as well as desirable oral absorption.Formula:C20H17F2NO3Purezza:98%Colore e forma:SolidPeso molecolare:357.35TC-AC28
CAS:TC-AC28 is a novel potent and selective Brd2(2) ligand.Formula:C23H21N5O3Purezza:98%Colore e forma:SolidPeso molecolare:415.44SIRT6-IN-3
CAS:SIRT6-IN-3 (compound 8a), a selective SIRT6 inhibitor (IC50 = 7.49 μM), impedes the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and promptsFormula:C21H30Br3ClN6SPurezza:98%Colore e forma:SolidPeso molecolare:673.73PARP7-probe-1
CAS:PARP7-probe-1: biotinylated, chemiluminescent PARP7 active site probe for research use.Formula:C36H49F3N8O5SColore e forma:SolidPeso molecolare:762.89MS31
CAS:MS31 is a potent and highly affinity inhibitor of spindlin 1 (SPIN1).Formula:C20H27N3O2Purezza:98%Colore e forma:SolidPeso molecolare:341.45Tyk2-IN-9
CAS:Tyk2-IN-9: selective Tyk-2 inhibitor, IC50 of 0.076 nM (TYK2-JH2), 1.8 nM (JAK1-JH2), for inflammation/autoimmune research.Formula:C20H17N9Purezza:98%Colore e forma:SolidPeso molecolare:383.41MAK683-CH2CH2COOH
CAS:MAK683-CH2CH2COOH, an EED-targeting chemical, serves as a foundation for EED degrader-1 and PROTAC EED degrader-2 design.Formula:C23H21FN6O3Purezza:98%Colore e forma:SolidPeso molecolare:448.45Compound SA91-0178
CAS:SA91-0178 (3-{[(1-methyl-2-oxo-1'-phenyl-1,2-dihydrospiro[indole-3,4'-piperidine]-5-carbonyl)amino]methyl}benzoic acid) is a specific METTL1 inhibitor and effectively alleviated tissue injury during septic inflammation.Formula:C28H27N3O4Peso molecolare:469.54GSK3368715 hydrochloride
CAS:GSK3368715, a first-in-class, orally active, potent, and selective SAM-noncompetitive inhibitor of Type I Protein Arginine Methyltransferases (PRMTs), exhibits anti-tumor efficacy across multiple cancer models and alters exon usage with IC50 values in the lower nM range. It synergizes with GSK3326595 (Type II inhibitor) (Axon 3750) to inhibit tumor growth.Formula:C20H38N4O2·HClColore e forma:SolidPeso molecolare:403MTDH-SND1 blocker 1
CAS:MTDH-SND1 Blocker 1 (Compound C26-A6) serves as an inhibitor targeting the MTDH-SND1 protein, effectively suppressing cancer metastasis [1].Formula:C14H13ClN4O3SColore e forma:SolidPeso molecolare:352.8
