Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2462 prodotti di "Cromatina/Epigenetica"
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Ten01
Ten01 exhibits a 5.0 nM inhibition of JAK1 kinase.Formula:C18H20F6N4OColore e forma:SolidPeso molecolare:422.37I-BET282E
I-BET282E inhibits eight BET bromodomains (pIC50 6.4-7.7) with selectivity for other bromodomain proteins.Formula:C26H34N4O7SColore e forma:SolidPeso molecolare:546.64OM-153
CAS:OM-153 blocks tankyrase 1 (IC50: 13 nM) and 2 (IC50: 2 nM), stifling WNT signaling and COLO 320DM cell growth.Formula:C28H24FN7O2Colore e forma:SolidPeso molecolare:509.53PF-06726304 acetate
CAS:PF-06726304 acetate is a selective inhibitor of EZH2, with robust antitumor growth activity.Formula:C24H25Cl2N3O5Purezza:98%Colore e forma:SolidPeso molecolare:506.38GDC-0339
CAS:GDC-0339: oral Pim kinase inhibitor for multiple myeloma (Kis: Pim1 - 0.03 nM, Pim2 - 0.1 nM, Pim3 - 0.02 nM), well-tolerated.Formula:C20H22F3N7OSColore e forma:SolidPeso molecolare:465.5HDAC-IN-27
HDAC-IN-27 is a potent and orally active inhibitor of HDAC Class I (0.43 nM - 3.01 nM for HDAC1-3).Formula:C20H22N4O2Colore e forma:SolidPeso molecolare:350.41HIF-1α-IN-4
HIF-1α-IN-4 is an inhibitor of HIF-1α with IC50 of 24 nM in HEK293T cells which has potential antitumor effects.Formula:C16H12N2O3Colore e forma:SolidPeso molecolare:280.28LSD1/HDAC-IN-1
CAS:LSD1/HDAC-IN-1 (compound 2) serves as an effective inhibitor of both HDAC and LSD1, demonstrating IC50 values of 0.125 nM, 0.373 nM, 0.0118 nM, 0.103 nM, and 0.571 μM for HDAC1, HDAC2, HDAC6, HDAC8, and LSD1 respectively. This compound plays a crucial role in cancer research.Formula:C18H18N2O4SColore e forma:SolidPeso molecolare:358.41SCR-7952
CAS:SCR-7952, a MAT2A inhibitor, is utilized in cancer research.Formula:C19H15ClN4OColore e forma:SolidPeso molecolare:350.80Enzomenib
CAS:Enzomenib (DSP5336), a menin protein inhibitor encoded by the multiple endocrine neoplasia (MEN) gene, blocks the interaction between menin protein and mixed lineage leukemia (MLL) fusion proteins. This compound is utilized in researching hematological malignancies.Formula:C33H43FN6O3Colore e forma:SolidPeso molecolare:590.73Cenacitinib
CAS:Cenacitinib is an effective inhibitor of Janus kinase (Janus kinase) and possesses anti-inflammatory activity.Formula:C19H19F2N7O3Colore e forma:SolidPeso molecolare:431.40BRD-7880
CAS:BRD-7880 is a potent and highly specific inhibitor of aurora kinases B and C.Formula:C32H38N4O7Colore e forma:SolidPeso molecolare:590.67MU1656
CAS:MU1656 is a selective inhibitor of histone methyltransferase DOT1L, which significantly inhibits cancer cell proliferation in hematological malignancies.Formula:C32H45N7O2Purezza:96.92%Colore e forma:SolidPeso molecolare:559.75YLIU-4-105-1
CAS:YLIU-4-105-1 is a type II JAK2 inhibitor. Demonstrating in vivo pharmacological activity, YLIU-4-105-1 reduces splenic weight, decreases blood reticulocyte counts in a dose-dependent manner, and inhibits pSTAT5.Formula:C32H34F3N7O2Colore e forma:SolidPeso molecolare:605.65O-Desmethyl Midostaurin
CAS:O-Desmethyl Midostaurin is the active Midostaurin metabolite via cytochrome P450 liver enzyme metabolism.Formula:C34H28N4O4Purezza:98%Colore e forma:SolidPeso molecolare:556.61MAT2A-IN-17
CAS:<p>MAT2A-IN-17 is a potent inhibitor of MAT2A, with an IC50 of less than 100 nM. MAT2A-IN-17 is applicable in cancer research.</p>Formula:C23H18F3N7OColore e forma:SolidPeso molecolare:465.431PFI-6-COOH
CAS:PFI-6-COOH (Compound 18) is a ligand for the eleven-nineteen leukemia (ENL) protein, and is utilized in the synthesis of the ENL PROTAC degrader MS41.Formula:C23H21N3O6Colore e forma:SolidPeso molecolare:435.43MI-1481
CAS:MI-1481: potent MML1 inhibitor, IC50 3.6 nM; disrupts menin-MLL1, active in MLL leukemia.Formula:C29H30F3N7O2SPurezza:98%Colore e forma:SolidPeso molecolare:597.65HLCL-61
CAS:HLCL-61 is a premier small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5).Formula:C23H24N2OColore e forma:SolidPeso molecolare:344.45KAT6A-IN-1
CAS:KAT6A-IN-1 (compound 5) is an inhibitor of KAT6A.Formula:C23H27N5O5SColore e forma:SolidPeso molecolare:485.56
