Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2442 prodotti di "Cromatina/Epigenetica"
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LY 170198
CAS:LY 170198 is a protein kinase C inhibitor.Formula:C22H25N5O5Purezza:98%Colore e forma:SolidPeso molecolare:439.46BRD4 Inhibitor-26
BRD4 Inhibitor-26: blocks BRD4 (BD1 and BD2) with IC50 of 0.82 μM & 1.94 μM; used in ovarian cancer research.Formula:C29H27N5O6SColore e forma:SolidPeso molecolare:573.62DHPCC-9
CAS:DHPCC-9 is an inhibitor of Pim kinase.Formula:C15H10N2OColore e forma:SolidPeso molecolare:234.25DC_501
CAS:DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.Formula:C25H23Cl2N3OPurezza:98%Colore e forma:SolidPeso molecolare:452.38DCE_254
CAS:DCE_254 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.Formula:C21H17N9OSPurezza:98%Colore e forma:SolidPeso molecolare:443.48Langkamide
CAS:Langkamide is a HIF-2 inhibitor with EC₅₀ values of 14.0 uM.Formula:C16H17NO5Purezza:98%Colore e forma:SolidPeso molecolare:303.31Dot1L-IN-7
CAS:Dot1L-IN-7 (compound 25), a potent DOT1L inhibitor with an IC50 of 1.0 μM, selectively kills MLL-AF9, sparing E2A-HLF cells.Formula:C23H27N9O2Colore e forma:SolidPeso molecolare:461.526-Methyl-5-azacytidine
CAS:6-Methyl-5-azacytidine is a potent DNMT inhibitor.Formula:C9H14N4O5Purezza:98%Colore e forma:SolidPeso molecolare:258.23BF1
CAS:BF1 is an inhibitor of HAT (histone acetyltransferase) active both in vitro and in vivo.Formula:C12H12ClN3SColore e forma:SolidPeso molecolare:265.76Farnesylthiotriazole
CAS:Farnesylthiotriazole is a persistent PKC activator agent.Formula:C17H27N3SPurezza:98%Colore e forma:SolidPeso molecolare:305.48Tenovin-D3
CAS:Tenovin-D3 is a sirtuin SirT2 inhibitor. It acts by increasing p21 (CDKN1A) expression in a p53-independent manner.Formula:C22H27Cl3N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:533.9ML399
CAS:ML399 inhibits menin–MLL interaction, selectively blocking oncogenic MLL signaling in leukemia cells, supporting functional genomics and therapeutic research.Formula:C27H28FN3O2Purezza:97.84% - 98.20%Colore e forma:SolidPeso molecolare:445.53Ref: TM-T24484
1mgPrezzo su richiesta5mg730,00€10mgPrezzo su richiesta25mg1.539,00€50mg1.941,00€100mg2.451,00€150mg2.565,00€NVS-BET-1
CAS:NVS-BET-1 is a BET bromodomain inhibitor. NVS-BET-1 can regulate keratinocyte plasticity.Formula:C22H21ClN4O2Colore e forma:SolidPeso molecolare:408.88HIF-IN-33
CAS:HIF-IN-33 is an inhibitor of HIF pathway.Formula:C21H17F3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:414.38TP-238
CAS:"TP-238: Potent CECR2/BPTF dual probe; IC50: 30 nM/350 nM. Inhibits BRD9 (pIC50: 5.9); minimal activity on 338 other kinases."Formula:C22H30N6O3SColore e forma:SolidPeso molecolare:458.58BET-BAY 002
CAS:BET-BAY 002 is an effective BET bromodomain inhibitor demonstrating efficacy in vivo and in vitro against multiple myeloma and leukaemia models.Formula:C22H18ClN5OColore e forma:SolidPeso molecolare:403.86Fagaronine chloride
CAS:Fagaronine chloride is a potent inhibitor of Topoisomerases I.Formula:C21H20ClNO4Colore e forma:SolidPeso molecolare:385.84Lobelane Hydrochloride
CAS:Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor.Formula:C22H30ClNColore e forma:SolidPeso molecolare:343.93SirReal-1
CAS:SirReal-1 is an effective and selective inhibitor of Sirt2.Formula:C18H18N4OS2Purezza:98%Colore e forma:SolidPeso molecolare:370.49Prospasmine
CAS:Prospasmine is an anticholinergic.Formula:C17H28ClNO2Purezza:98%Colore e forma:SolidPeso molecolare:313.87BRD4-BD1-IN-1
CAS:BRD4-BD1-IN-1 (Compound 9a) is a BRD4-BD1 inhibitor(IC50= 38.20 μM).Formula:C16H15BrN4O4Colore e forma:SolidPeso molecolare:407.22Hns 32
CAS:Hns 32 possesses antiarrhythmic properties in dog and guinea pig hearts. It also has vasodilator action.Formula:C24H29N3Purezza:98%Colore e forma:SolidPeso molecolare:359.51PI3K/HDAC-IN-1
CAS:<p>PI3K/HDAC-IN-1 is a potent PI3K and HDAC dual inhibitor(IC50s of 8.1 nM and 1.4 nM, respectively).</p>Formula:C22H25FN4O4Purezza:98%Colore e forma:SolidPeso molecolare:428.46INCB054329 Racemate
CAS:INCB054329 Racemate is an inhibitor of BET protein.Formula:C19H16N4O3Purezza:98%Colore e forma:SolidPeso molecolare:348.36BRD4 Inhibitor-19
CAS:BRD4 inhibitors -19 are BET inhibitors that act on BRD4-BD1 (IC50: 55 nM) and can be used to study multiple myeloma.Formula:C29H25N5O3Colore e forma:SolidPeso molecolare:491.54CBHA
CAS:m-Carboxycinnamic bishydroxamide: HDAC inhibitor, ID50 = 10 nM (HDAC1), 70 nM (HDAC3), induces apoptosis and tumor growth suppression.Formula:C10H10N2O4Colore e forma:SolidPeso molecolare:222.2TK4g
CAS:TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) & 15.80 nM (JAK3); promising for lymphoid diseases & leukemia research.Formula:C19H19N3O4SColore e forma:SolidPeso molecolare:385.44NSC-311068
CAS:NSC-311068: A selective TET1 inhibitor, reducing 5hmC and AML cell viability with high TET1.Formula:C10H6N4O4SColore e forma:SolidPeso molecolare:278.24TyK2-IN-2
CAS:TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).Formula:C16H18N6OPurezza:98%Colore e forma:SolidPeso molecolare:310.35ABT-472
CAS:ABT-472 is a novel PARP inhibitorFormula:C20H28N4O5Colore e forma:SolidPeso molecolare:404.46GSK926
CAS:GSK926 is a selective, SAM-competitive, and cell-active EZH2 inhibitor.Formula:C29H35N7O2Colore e forma:SolidPeso molecolare:513.63YUKA1
CAS:YUKA1, a cell-permeable KDM5A inhibitor with a weak effect on KDM5C, increase H3K4me3 and inhibit the proliferation, prevent drug-resistant.Formula:C13H16N4O2SPurezza:99.85%Colore e forma:SolidPeso molecolare:292.36Ref: TM-T17278
1mg111,00€5mg264,00€10mg432,00€25mg847,00€50mg1.293,00€100mg1.882,00€200mg2.593,00€1mL*10mM (DMSO)283,00€CREBBP-IN-9
CAS:CREBBP-IN-9, a CREBBP inhibitor, acts on the bromodomain of the protein.Formula:C16H15N5O2SPurezza:98%Colore e forma:SolidPeso molecolare:341.39CP-690550A
CAS:Cp-690550a is a novel JAK3 inhibitor, which is used to treat rheumatoid arthritis, graft rejection, psoriasis, and other immune-mediated diseases.Formula:C15H21N5O2Colore e forma:SolidPeso molecolare:303.36SDR-04
CAS:SDR-04 inhibits BRD4-BD1 with high affinity, suppressing MV4;11 cancer cell growth as a BET inhibitor.Formula:C19H16N4O2Colore e forma:SolidPeso molecolare:332.36H8-A5
CAS:H8-A5, a HDAC8 inhibitor, shows antiproliferation activity in MDA-MB-231 cancer cells.Formula:C14H9F3N2O2SPurezza:98%Colore e forma:SolidPeso molecolare:326.29CPI703
CAS:CPI703 is a novel potent and specific CBP/EP300 bromodomain inhibitor.Formula:C17H22N4OPurezza:98%Colore e forma:SolidPeso molecolare:298.38PARP1-IN-11
CAS:PARP1-IN-11 is a potent PARP1 inhibitor (IC50=0.082 μM), also reducing PARP3, TNKS1, and TNKS2 activity.Formula:C16H12N2O4Colore e forma:SolidPeso molecolare:296.28KDM2B-IN-3
CAS:KDM2B-IN-3, from patent WO2016112284A1 as compound 183c, potently inhibits histone demethylase KDM2B, with cancer research potential.Formula:C25H30N2O2Colore e forma:SolidPeso molecolare:390.52Arazine
CAS:Arazine, a cell-permeable G protein modulator, is an isoprenylcysteine methyltransferase substrate.Formula:C20H33NO3SPurezza:90%Colore e forma:SolidPeso molecolare:367.55UNC2327
CAS:UNC2327 is a potent and selective inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50:230 nM).Formula:C14H17N5O2SPurezza:98%Colore e forma:SolidPeso molecolare:319.38OHM1
CAS:OHM1, an analog of HIF1α CTAD, effectively inhibits the interaction between HIF1α CTAD and p300/CBP by targeting the CH1 domain with a binding affinity of 0.53Formula:C24H42N6O5Colore e forma:SolidPeso molecolare:494.63MS453
CAS:MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.Formula:C20H27N5O3Colore e forma:SolidPeso molecolare:385.46ARTD10/PARP10-IN-2
CAS:ARTD10/PARP10-IN-2: A potent, non-selective PARP inhibitor, IC50: ARTD10/PARP10 (2.0μM), ARTD1/PARP1 (9.7μM).Formula:C12H13N3O3Colore e forma:SolidPeso molecolare:247.25BAY1238097
CAS:BAY1238097 is a BET inhibitor with anticancer activity and antiproliferative activity for the study of advanced refractory malignancies.Formula:C25H33N5O3Purezza:98.1% - 98.79%Colore e forma:SolidPeso molecolare:451.56Ref: TM-T12660L
1mg51,00€5mg106,00€10mg175,00€25mg375,00€50mg655,00€100mg1.103,00€200mg1.483,00€1mL*10mM (DMSO)119,00€CMP-5 hydrochloride
CAS:CMP-5 hydrochloride: potent, selective PRMT5 inhibitor; inactive against PRMT1/4/7; blocks S2Me-H4R3 on histones.Formula:C21H22ClN3Purezza:98%Colore e forma:SolidPeso molecolare:351.87Dimethyl-bisphenol A
CAS:DMBPA inhibits HIF-1α, promotes its degradation by detaching Hsp90, and reduces Vegfa mRNA expression.Formula:C17H20O2Colore e forma:SolidPeso molecolare:256.34JS1310
CAS:JS1310 is a selective PRMT7 inhibitor (IC50: 5 μM against human PRMT7). JS1310 has shown anti-cancer effects on different cancer cells.Formula:C23H22FN5O3Colore e forma:SolidPeso molecolare:435.45HDAC3-IN-T247
CAS:HDAC3-IN-T247 (HDAC3 inhibitor T247) is a histone deacetylase 3 (HDAC3) inhibitor with antiviral activity that inhibits the proliferation of cancer cells.Formula:C21H19N5OSPurezza:98.11% - 98.94%Colore e forma:SolidPeso molecolare:389.47Ref: TM-T24131
1mg92,00€5mg188,00€10mg311,00€25mg643,00€50mg914,00€100mg1.216,00€1mL*10mM (DMSO)215,00€JAK-IN-14
CAS:JAK-IN-14 (compound 16) is a specific JAK1 inhibitor. It prevents JAK1 phosphorylation by binding to the active site of JAK in immune, inflammation and cancer.Formula:C19H15FN4OPurezza:98.27%Colore e forma:SolidPeso molecolare:334.35Ref: TM-T9764
1mg86,00€5mg180,00€10mg283,00€25mg587,00€50mg938,00€100mg1.491,00€200mg1.985,00€1mL*10mM (DMSO)188,00€
