Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2441 prodotti di "Cromatina/Epigenetica"
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PRMT5-IN-18
CAS:PRMT5-IN-18 (Compound 002) is a potent inhibitor of PRMT5 and can be used in the study of PRMT5-mediated diseases, such as tumours.Formula:C32H42N4O4Colore e forma:SolidPeso molecolare:546.70LSD1/2-IN-4
LSD1/2-IN-4, a PCPA derivative, inhibits LSD1 (Ki 0.11 μM) & LSD2 (Ki 130 μM), potentially useful in T-cell leukemia research.Formula:C9H8BrF2NColore e forma:SolidPeso molecolare:248.07PAD-IN-2
CAS:PAD-IN-2, potent PAD4 inhibitor, IC50 <1 μM; targets autoimmune/cancer disorders.Formula:C27H28ClN5O2Colore e forma:SolidPeso molecolare:490LSD1-IN-13 hydrochloride
CAS:LSD1-IN-13 hydrochloride (7e) is an oral LSD1 inhibitor (IC50: 24.43 nM), promoting differentiation in AML cell lines.Formula:C23H30ClN3O2SColore e forma:SolidPeso molecolare:448.02ROPA
CAS:ROPA, a potent PKCalpha and PKCgamma activator, promotes tumor growth through PKC-activation.Formula:C28H32O6Purezza:98%Colore e forma:SolidPeso molecolare:464.55MC2652
MC2652, a potent LSD1 inhibitor, suppresses leukemia (MV4-11, NB4) and impedes prostate cancer (LNCaP) cell growth.Formula:C22H20N2OColore e forma:SolidPeso molecolare:328.41ATR kinase-IN-2
CAS:ATRkinase-IN-2 (Compound I-G-27) is an inhibitor of the ATR protein kinase, with a Ki value ranging from 0.01 to 1 μΜ. It is utilized in tumor research.Formula:C24H29F2N9O2Colore e forma:SolidPeso molecolare:513.54HDAC6-IN-13
HDAC6-IN-13: potent, selective HDAC6 inhibitor; oral; IC50=0.019μM; targets HDAC1/2/3; crosses blood-brain barrier; anti-inflammatory.Formula:C23H22N4OColore e forma:SolidPeso molecolare:370.45PARP14 inhibitor 1
CAS:<p>PARP14 inhibitor1 (compound Q22) is a selective inhibitor of PARP14 with an IC50 of 5.52 nM. It also exhibits anti-inflammatory properties and has a half-life of 182 minutes in mouse liver microsomes. This compound is applicable for atopic dermatitis research.</p>Formula:C23H27FN4O3Colore e forma:SolidPeso molecolare:426.484NSD2-PWWP1-IN-3
CAS:<p>NSD2-PWWP1-IN-3 (compound 36) is an effective inhibitor of NSD2-PWWP1, with an IC50 value of 8.05 µM. It has potential applications in cancer research.</p>Formula:C34H39N5O2Colore e forma:SolidPeso molecolare:549.706AZ0108
CAS:AZ0108, an oral PARP1,2,6 inhibitor, selectively blocks centrosome clustering, is viable for in vivo studies, and doesn't inhibit PARP3/TNKS1.Formula:C24H20F4N6O2Colore e forma:SolidPeso molecolare:500.45ER272
CAS:ER272 is a natural PKC activator, inducing hippocampal neurogenesis.Formula:C24H34O6Colore e forma:SolidPeso molecolare:418.52TK-129
TK-129: Oral KDM5B inhibitor, IC50=44 nM, low-toxicity, cardioprotective, aids in heart disease research.Formula:C15H23N5O2Colore e forma:SolidPeso molecolare:305.38HDAC6-IN-12
HDAC6-IN-12 is a potent inhibitor of HDAC6 that binds in the DNA chain, causing DNA damage and exhibiting anticancer effects that can be used in cancer researchFormula:C24H39F2N3O5Colore e forma:SolidPeso molecolare:487.58HDAC/HSP90-IN-4
HDAC/HSP90-IN-4 inhibits HDAC (20 IC50=194nM, 26 IC50=360nM) & HSP90α (20 IC50=153nM, 26 IC50=77nM), affects cancer cell survival and invasion.Formula:C20H23N3O6Colore e forma:SolidPeso molecolare:401.15869CBP/p300-IN-16
CBP/p300-IN-16 (compound 1) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.61 μM) and LK2 H3K27 (IC50: 2.24 μM).Formula:C26H31N3O4Colore e forma:SolidPeso molecolare:449.54PARP1-IN-5
PARP1-IN-5 is a potent, selective, orally active, low-toxicity PARP-1 inhibitor with an IC50 value of 14.7 nM. PARP1-IN-5 can be used in cancer research.Formula:C25H24N2O5SColore e forma:SolidPeso molecolare:464.53RK-582
CAS:RK-582: oral spiroindolinone tankyrase inhibitor, halts colon cancer growth in COLO-320DM mouse model.Formula:C27H35FN6O3Colore e forma:SolidPeso molecolare:510.6PARP10/15-IN-1
PARP10/15-IN-1 (compound 8l) is a dual PARP10 and PARP15 inhibitor with IC50s of 160 nM and 370 nM, respectively. It can be used in cancer research[1].Formula:C13H10N2O3SColore e forma:SolidPeso molecolare:274.3(2S,3R)-LP99
CAS:(2S,3R)-LP99 is a less active enantiomer of LP99.Formula:C26H30ClN3O4SPurezza:98%Colore e forma:SolidPeso molecolare:516.05
