Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2441 prodotti di "Cromatina/Epigenetica"
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SJ988497
CAS:SJ988497: PROTAC JAK2 degrader, inhibits CRLF2r cell growth, degrades GSPT1, combines Ruxolitinib, linker, Pomalidomide; researched for ALL.Formula:C36H36N10O5Colore e forma:SolidPeso molecolare:688.74Malantide
CAS:Malantide, a synthetic dodecapeptide, boosts and measures PKA activity by undergoing PKA-induced phosphorylation.Formula:C72H124N22O21Purezza:98%Colore e forma:SolidPeso molecolare:1633.89Cath-L-dBET1
Cath-L-dBET1 is a PROTAC degrader targeting BRD4. It has an IC50 value of 2.8 μM in MDA-MB-231 cells. Activated by cathepsin L (Cath-L), Cath-L-dBET1 recruits E3 ubiquitin ligase to degrade BRD4 via the ubiquitin-proteasome system. Hyp-dBET1 is applicable for antitumor research.Colore e forma:Odour SolidThalidomide-NH-CBP/p300 ligand 2
CAS:Thalidomide-NH-CBP/p300 ligand 2 (P-007) is a PROTAC-based compound designed to degrade CBP and p300, acting as a functional antagonist (WO2020173440).Formula:C48H57F2N11O6Colore e forma:SolidPeso molecolare:922.052RMM23
RMM23 is an inhibitor that targets PfBDP1, exhibiting a Kd of 1.24 μM. In vitro, it shows EC50 values of 18 μM against the 3D7 wild-type strain, 14 μM against the NF54 wild-type strain, and 20 μM against the multidrug-resistant K1 strain during the blood stage.Colore e forma:Odour Solid7-Hydroxyneolamellarin A
CAS:7-Hydroxyneolamellarin A, from Dendrilla nigra, inhibits HIF-1α and VEGF in cancer research.Formula:C24H19NO5Colore e forma:SolidPeso molecolare:401.41SIRT1-IN-1
CAS:SIRT1-IN-1 is a selective inhibitor of SIRT1 with an IC50 of 205 nM.Cost-effective and quality-assured.Formula:C14H16N2OPurezza:99.58%Colore e forma:SolidPeso molecolare:228.29Ref: TM-T9648
1mg96,00€5mg202,00€10mg311,00€25mg533,00€50mg747,00€100mg1.017,00€200mg1.359,00€1mL*10mM (DMSO)207,00€PROTAC HDAC6 degrader 3
PROTACHDAC6 degrader 3 (Compound 4) is a selective inhibitor and degrader of HDAC6, with an IC50 of 686 nM and a DC50 of 171 nM. It enhances the acetylation of α-tubulin. [Pink: ligand for target protein; Blue: ligand for E3ligaseVHL.]Formula:C46H56F2N10O9SColore e forma:SolidPeso molecolare:963.06SIRT5 inhibitor 9
CAS:SIRT5 inhibitor 9 (compound 14) is a moderately selective and substrate-competitive SIRT5 inhibitor with IC50=4.07 μM and has potential anticancer effects.Formula:C24H29ClN8O4SPurezza:98.68%Colore e forma:SolidPeso molecolare:561.06VinSpinIn
CAS:VinSpinIn is a probe for the Spin family proteins.Formula:C42H58N8O4Colore e forma:SolidPeso molecolare:738.98FKBP12 PROTAC dTAG-7
CAS:dTAG-7 selectively degrades BRD4 and FKBP12F36V by linking BET bromodomains to E3 ligase CRBN; it's a heterobifunctional degrader.Formula:C63H79N5O19Purezza:98%Colore e forma:SolidPeso molecolare:1210.32PROTAC BET Degrader-10
CAS:PROTAC BET Degrader-10 targets and degrades BRD4 with a DC50 of 49 nM, using Cereblon ligands.Formula:C39H39ClN8O6SColore e forma:SolidPeso molecolare:783.3Ref: TM-T39374
5mg236,00€10mg379,00€25mg710,00€50mg1.054,00€100mg1.568,00€200mgPrezzo su richiesta500mgPrezzo su richiesta1mL*10mM (DMSO)326,00€SJ10542
CAS:SJ10542: potent JAK2/3-targeting PG-PROTAC; DC50s: JAK2 - 14 nM, JAK3 - 11 nM, JAK2-fusion ALL - 24 nM; CRBN recruiter.Formula:C41H46N12O5SColore e forma:SolidPeso molecolare:818.95PROTAC BRM degrader-1
CAS:PROTAC BRM degrader-1 (compound 17) serves as a PROTAC-based degrader targeting both BRM and BRG1, exhibiting DC50 values of 93 pM and 4.9 nM, respectively [1].Formula:C57H69N11O8SColore e forma:SolidPeso molecolare:1068.29(rel)-Tranylcypromine D5 hydrochloride
CAS:(rel)-Tranylcypromine D5 hydrochloride is a deuterium labeled (rel)-Tranylcypromine hydrochloride.Formula:C9H12ClNPurezza:98%Colore e forma:SolidPeso molecolare:174.682Fluorescein-NAD+
Fluorescein NAD+ is a non-radioactive PARP assay substrate, enabling direct enzyme measurement by fluorescence. Comes as 81μg in 250μl water.Colore e forma:SolidMz325
Mz325 serves as a dual inhibitor of both HDAC and Sirt2, exhibiting an IC50 of 9.7 µM against Sirt2, which are implicated in the pathogenesis of cancer andPurezza:98%Colore e forma:Odour SolidEZH2-IN-15
CAS:A compound inhibits EZH2, overexpressed in cancers, affecting Treg activity and innate immunity.Formula:C32H44N4O4Purezza:99.88%Colore e forma:SolidPeso molecolare:548.72Ref: TM-T67883
1mg143,00€5mg344,00€10mg525,00€25mg833,00€50mg1.121,00€100mg1.510,00€200mg2.023,00€1mL*10mM (DMSO)418,00€JAK3-IN-15
JAK3-IN-15 (compound 22) is a JAK3 inhibitor that reduces the secretion of p-JAK3 induced by LPS. It is utilized in research for rheumatoid arthritis.Colore e forma:Odour SolidE67-2
CAS:E67-2: Low-toxic, KIAA1718 inhibitor with IC50 of 3.4μM, targets H3K9/H3K4 demethylases.Formula:C21H36N6O2Colore e forma:SolidPeso molecolare:404.559
