Cromatina/Epigenetica
Gli inibitori della cromatina/epigenetica sono composti che modulano la struttura e la funzione della cromatina o interferiscono con le modificazioni epigenetiche, come la metilazione del DNA e la modifica degli istoni. Questi inibitori sono strumenti essenziali per studiare la regolazione dell'espressione genica e il ruolo dell'epigenetica in malattie come il cancro, i disturbi neurologici e le anomalie dello sviluppo. Mirando ai processi epigenetici, questi inibitori possono alterare i modelli di espressione genica e offrire nuove opportunità terapeutiche. Presso CymitQuimica, offriamo un'ampia selezione di inibitori della cromatina/epigenetica di alta qualità per supportare le tue ricerche in biologia molecolare, genetica ed epigenetica.
Sottocategorie di "Cromatina/Epigenetica"
Trovati 2597 prodotti di "Cromatina/Epigenetica"
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TP0463518
CAS:TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 nM for human and rat PHD2, respectively).Formula:C20H18ClN3O6Purezza:99.52%Colore e forma:SolidPeso molecolare:431.83Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purezza:99.97% - >99.99%Colore e forma:SolidPeso molecolare:346.42Ref: TM-T4672
1mg90,00€5mg203,00€10mg350,00€25mg578,00€50mg797,00€100mg1.071,00€500mg2.187,00€1mL*10mM (DMSO)224,00€RGB-286638 free base
CAS:RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formula:C29H35N7O4Purezza:98% - 99.91%Colore e forma:SolidPeso molecolare:545.63Windorphen
CAS:Windorphen is a Wnt inhibitor that selectively abrogates the Wnt signaling.Formula:C17H15ClO3Purezza:99.66%Colore e forma:SolidPeso molecolare:302.75Fedratinib hydrochloride hydrate
CAS:Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.Formula:C27H40Cl2N6O4SPurezza:98.96% - 99.87%Colore e forma:SolidPeso molecolare:615.61ME0328
CAS:ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.Formula:C19H19N3O2Purezza:99.22%Colore e forma:SolidPeso molecolare:321.37DL-α-Hydroxyglutaric acid disodium salt
CAS:DL-α-Hydroxyglutaric acid disodium salt (disodium 2-hydroxypentanedioate) is an α -hydroxyacid formed from the hydrolysis of (R) -5-oxy-2-tetrahydrofuranFormula:C5H6Na2O5Purezza:≥98%Colore e forma:SolidPeso molecolare:192.08ASP4132
CAS:ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.Formula:C46H51F3N6O8S2Purezza:98.34%Colore e forma:SolidPeso molecolare:937.06Ref: TM-T8432
1mg50,00€5mg114,00€10mg177,00€25mg321,00€50mg482,00€100mg677,00€200mg928,00€1mL*10mM (DMSO)185,00€PF-06409577
CAS:PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).Formula:C19H16ClNO3Purezza:95.17% - 98.21%Colore e forma:SolidPeso molecolare:341.79Ref: TM-T4427
1mg34,00€2mg43,00€5mg63,00€10mg100,00€25mg200,00€50mg334,00€100mg537,00€200mg762,00€1mL*10mM (DMSO)71,00€AG490
CAS:AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Formula:C17H14N2O3Purezza:98.6% - 99.85%Colore e forma:Yellow SolidPeso molecolare:294.3EPZ005687
CAS:EPZ005687 is a potent and selective inhibitor of EZH2.Formula:C32H37N5O3Purezza:97.06% - 99.64%Colore e forma:SolidPeso molecolare:539.67XL019
CAS:XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.Formula:C25H28N6O2Purezza:99.19%Colore e forma:SolidPeso molecolare:444.53Ref: TM-T3072
2mg46,00€5mg66,00€10mg97,00€25mg159,00€50mg226,00€100mg339,00€200mg502,00€1mL*10mM (DMSO)82,00€Filgotinib
CAS:Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formula:C21H23N5O3SPurezza:98.03% - ≥95%Colore e forma:SolidPeso molecolare:425.5OG-L002
CAS:OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.Formula:C15H15NOPurezza:97.05% - 98.62%Colore e forma:SolidPeso molecolare:225.29BEBT-908
CAS:BEBT-908 (PI3Kα inhibitor 1) is a selective PI3Kα inhibitor (IC50 <0.1 μM). BEBT-908 also inhibits HDAC (0.1 μM≤IC50≤1 μM).Formula:C23H25N9O3SPurezza:99.67%Colore e forma:SolidPeso molecolare:507.57Ref: TM-T16529
1mg94,00€5mg222,00€10mg334,00€25mg562,00€50mg802,00€100mg1.063,00€200mg1.459,00€1mL*10mM (DMSO)249,00€PF-CBP1 hydrochloride
CAS:PF-CBP1 HCl selectively inhibits CREBBP bromodomain (IC50: 125 nM) and p300 (IC50: 363 nM).Formula:C29H37ClN4O3Purezza:97.11% - 99.02%Colore e forma:SolidPeso molecolare:525.08Delgocitinib EtOH
CAS:Delgocitinib (LEO-124249/JTE052) is a selective JAK inhibitor used for reducing skin inflammation and treating chronic dermatitis.Formula:C18H24N6O2Colore e forma:SolidPeso molecolare:356.43Danusertib
CAS:Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Formula:C26H30N6O3Purezza:97.88% - 98.79%Colore e forma:White PowderPeso molecolare:474.55MPT0G211 mesylate
CAS:MPT0G211 mesylate: potent, selective HDAC6 inhibitor (IC50=0.291nM), oral, BBB-penetrating, anti-tau and metastasis, potential anticancer.Formula:C18H19N3O5SColore e forma:SolidPeso molecolare:389.43
