Metiltransferasi del DNA
Le metiltransferasi del DNA (DNMT) sono enzimi che catalizzano l'aggiunta di gruppi metilici ai residui di citosina nel DNA, portando al silenziamento genico. Una metilazione aberrante del DNA è associata a varie malattie, incluso il cancro. Gli inibitori delle DNMT bloccano l'attività di questi enzimi, portando alla riattivazione dei geni silenziati e all'induzione dell'apoptosi nelle cellule tumorali. Gli inibitori delle DNMT sono ampiamente utilizzati nella ricerca epigenetica e nella terapia del cancro. Presso CymitQuimica, offriamo una gamma di inibitori delle DNMT di alta qualità per supportare la tua ricerca in epigenetica, metilazione del DNA e biologia del cancro.
Trovati 455 prodotti di "Metiltransferasi del DNA"
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Zebularine
CAS:Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.Formula:C9H12N2O5Purezza:99.04% - >99.99%Colore e forma:SolidPeso molecolare:228.2UNC0642
CAS:UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).Formula:C29H44F2N6O2Purezza:98.75% - 99.5%Colore e forma:SolidPeso molecolare:546.7Ref: TM-T4166
1mg40,00€2mg52,00€5mg87,00€10mg131,00€25mg230,00€50mg378,00€100mg567,00€200mg825,00€1mL*10mM (DMSO)95,00€SETDB1-TTD-IN-1
CAS:SETDB1-TTD-IN-1 is a potent and selective inhibitor of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD, Kd = 88 nM).Cost-effective and quality-assured.Formula:C28H31N5O2Purezza:98.26% - 99.96%Colore e forma:SolidPeso molecolare:469.58EED226
CAS:EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.Formula:C17H15N5O3SPurezza:98.14% - 99.33%Colore e forma:SolidPeso molecolare:369.4Succinic acid sodium
CAS:Succinic acid sodium is an orally active anxiolytic.Formula:C4H6O4·xNaColore e forma:Solidγ-Oryzanol
CAS:γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in theFormula:C40H58O4Purezza:mixture - mixtureColore e forma:White Or White Crystalline Powder OdourlessPeso molecolare:602.9SGC2085
CAS:SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).Formula:C19H24N2O2Purezza:99.61% - 99.71%Colore e forma:SolidPeso molecolare:312.41Ref: TM-T7089
1mg88,00€2mg119,00€5mg227,00€10mg341,00€25mg563,00€50mg820,00€100mg1.130,00€1mL*10mM (DMSO)160,00€OTS186935 hydrochloride
OTS186935 HCl inhibits SUV39H2 (IC50 6.49 nM), curbs tumor growth in mice, and modulates γ-H2AX in cancer cells.Formula:C25H27Cl2N5O2Colore e forma:SolidPeso molecolare:522.31BIX-01294
CAS:BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).Formula:C28H38N6O2Purezza:98.58% - 99.64%Colore e forma:SolidPeso molecolare:490.64Ref: TM-T7697
1mg40,00€5mg85,00€10mg117,00€25mg207,00€50mg311,00€100mg472,00€200mg642,00€1mL*10mM (DMSO)131,00€UNC1215
CAS:UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).Formula:C32H43N5O2Purezza:98% - 99.04%Colore e forma:SolidPeso molecolare:529.72SGC0946
CAS:SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.Formula:C28H40BrN7O4Purezza:98% - 99.82%Colore e forma:SolidPeso molecolare:618.57Gambogenic acid
CAS:Gambogenic acid is a natural product,is an effective inhibitor of EZH2,with anticancer activity.Formula:C38H46O8Purezza:97.47% - 99.6%Colore e forma:SolidPeso molecolare:630.77Ref: TM-T8201
1mg49,00€5mg97,00€10mg160,00€25mg283,00€50mg452,00€100mg723,00€200mg938,00€1mL*10mM (DMSO)135,00€EPZ004777
CAS:EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.Formula:C28H41N7O4Purezza:98.99% - 99.32%Colore e forma:SolidPeso molecolare:539.67A-196
CAS:A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective overFormula:C18H16Cl2N4Purezza:99.92%Colore e forma:SolidPeso molecolare:359.25UNC0646
CAS:UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP with low cellular toxicity.Formula:C36H59N7O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:621.9CM-579 trihydrochloride
CM-579 trihydrochloride: reversible G9a/DNMT inhibitor with IC50s 16 nM (G9a) & 32 nM (DNMT); potent against various cancer cells.Formula:C29H43Cl3N4O3Colore e forma:SolidPeso molecolare:602.04WDR5-0103
CAS:WDR5-0103 (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd: 450 nM).Formula:C21H25N3O4Purezza:98% - 99.61%Colore e forma:SolidPeso molecolare:383.44AZ505
CAS:AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).Formula:C29H38Cl2N4O4Purezza:98.18%Colore e forma:SolidPeso molecolare:577.54Ref: TM-TQ0100
1mg64,00€5mg137,00€10mg188,00€25mg311,00€50mg487,00€100mg658,00€1mL*10mM (DMSO)168,00€PF-06726304
CAS:PF-06726304: potent EZH2 inhibitor, effective against tumors, Kis at 0.7 nM (wild-type) and 3.0 nM (Y641N mutant).Formula:C22H21Cl2N3O3Purezza:98.19% - 99.51%Colore e forma:SolidPeso molecolare:446.33Ref: TM-T12428L
1mg39,00€2mg50,00€5mg81,00€10mg125,00€25mg279,00€50mg505,00€100mg730,00€1mL*10mM (DMSO)88,00€Piribedil
CAS:Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.Formula:C16H18N4O2Purezza:99.79% - 99.82%Colore e forma:SolidPeso molecolare:298.34
