Endocrinologia/Ormoni
Gli inibitori dell'endocrinologia/oromone sono composti che bloccano l'azione degli ormoni o interferiscono con le vie di segnalazione ormonale. Questi inibitori sono fondamentali per studiare la regolazione dei sistemi endocrini e per sviluppare trattamenti per malattie correlate agli ormoni, come il diabete, i disturbi della tiroide e i tumori ormono-dipendenti. Modulando l'attività ormonale, questi inibitori possono aiutare a chiarire le complesse interazioni all'interno del sistema endocrino. Presso CymitQuimica, offriamo un'ampia gamma di inibitori di alta qualità per endocrinologia/oromone per supportare le tue ricerche in endocrinologia, farmacologia e scienze mediche.
Sottocategorie di "Endocrinologia/Ormoni"
- Recettore degli androgeni(229 prodotti)
- Annessina A(16 prodotti)
- Aromatasi(22 prodotti)
- Recettore degli estrogeni/progestogeni(56 prodotti)
- GPR(1 prodotti)
- Recettore dei glucocorticoidi(166 prodotti)
- LHRH(1 prodotti)
- Recettore degli oppioidi(326 prodotti)
- Recettore della prostaglandina(122 prodotti)
- RAAS(90 prodotti)
- Riduttasi(50 prodotti)
- Somatostatina(57 prodotti)
- Recettore dell'ormone tiroideo (THR)(32 prodotti)
- Recettore della vasopressina(47 prodotti)
Mostrare 6 più sottocategorie
Trovati 3370 prodotti di "Endocrinologia/Ormoni"
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L 365209
CAS:L 365209 is an oxytocin antagonist.Formula:C40H50N8O6Purezza:98%Colore e forma:SolidPeso molecolare:738.88Mu opioid receptor antagonist 3
Potent, selective MOR antagonist (compound 26); crosses blood-brain barrier. Ki: 0.24 nM, EC50: 0.54 nM; for studying OUD.Formula:C25H28N2O4SColore e forma:SolidPeso molecolare:452.57Emd 52297
CAS:Emd 52297 is an inhibitor of renin.Formula:C39H59N11O7Purezza:98%Colore e forma:SolidPeso molecolare:793.96AT1R antagonist 2
AT1R antagonist 2 is a potent AT1R selective ligand with good AT1R affinity (Ki: 26 nM).Formula:C29H37N5O4S2Colore e forma:SolidPeso molecolare:583.77MTI013
MTI013 is a selective inhibitor of SARS-CoV-2 nsp14 Mtase (IC50: 2.98 µM) and an antiviral agent (IC50: 10.33 µM in HCoV-229E infected Huh7 cells). Additionally, MTI013 demonstrates synergistic antiviral effects when used in conjunction with the RdRp inhibitor SHEN26.Formula:C24H26N6O4SColore e forma:SolidPeso molecolare:494.57A4B17
A4B17 is an inhibitor of androgen receptor N-terminal with potential for androgen-responsive prostate cancer treatment.Formula:C14H7F4NSColore e forma:SolidPeso molecolare:297.27Pentomone
CAS:Pentomone (LY-113935) is an anti-androgen compound that acts as a prostate growth inhibitor.Formula:C24H26O5Colore e forma:SolidPeso molecolare:394.46ER degrader 10
CAS:<p>ER degrader 10 (Compound 51) is an orally active estrogen receptor (ER) selective degrader and antagonist, with a DC50 of 0.43 nM and an IC50 of 0.56 nM. It inhibits the proliferation of ER-positive cells, with an IC50 ranging from 0 to 15 nM. ER degrader 10 exhibits weak inhibitory activity on the hERG channel, with an IC50 greater than 40 μM. It has blood-brain barrier permeability, with a brain/plasma ratio (Kp) of 3.05. In mouse models, ER degrader 10 demonstrates antitumor activity.</p>Formula:C28H29F2NO3SColore e forma:SolidPeso molecolare:497.597ERα degrader 11
CAS:ERα degrader11 (compound B16) is a selective estrogen receptor degrader designed for use as a probe in examining the ER status within ER-positive breast cancer cells.Formula:C28H27F3N2O3Colore e forma:SolidPeso molecolare:496.52ADX61623
CAS:ADX61623 is an effective negative allosteric modulator (NAM) of the follicle-stimulating hormone receptor (FSHR). It also exhibits activity on the luteinizing hormone receptor (LH-R) but is inactive on the thyroid-stimulating hormone (TSH) receptor. ADX61623 can be utilized in research on estrogen-dependent diseases.Formula:C19H20N2O3Colore e forma:SolidPeso molecolare:324.37ACT 178882
CAS:ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).Formula:C33H38Cl3N3O4Purezza:98%Colore e forma:SolidPeso molecolare:647.03Allyphenyline oxalate
CAS:<p>The pKi values of Allyphenyline oxalate (compound 9) for the α2-adrenergic receptor subtypes α2A, α2B, and α2C are 7.24, 6.47, and 7.07, respectively.</p>Formula:C16H20N2O5Colore e forma:SolidPeso molecolare:320.34BU09059
CAS:BU09059 is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR).Formula:C28H37N3O5Purezza:98%Colore e forma:SolidPeso molecolare:495.61Norbinaltorphimine dihydrochloride
CAS:Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses in mice.Formula:C40H45Cl2N3O6Purezza:98.17% - 99.88%Colore e forma:SolidPeso molecolare:734.71Ref: TM-T12241
1mg38,00€5mg85,00€10mg120,00€25mg235,00€50mg409,00€100mg652,00€200mg908,00€1mL*10mM (DMSO)124,00€Naldemedine tosylate
CAS:Naldemedine (S-297995) tosylate, a PAMORA, targets μ-, δ-, κ-opioid receptors, aiding OIC research, may bind to SARS-CoV2's 3CL pro.Formula:C39H42N4O9SColore e forma:SolidPeso molecolare:742.84Glucocorticoid receptor activator 1
CAS:Glucocorticoid Receptor Activator 1, a phenyl nitrogen-heterocyclic precursor, acts as an activator of the glucocorticoid receptor (GR). By activating GR, it downregulates the expression of pro-inflammatory genes stimulated by TNF, making it useful for inflammation research.Formula:C11H15Cl2NO2Colore e forma:SolidPeso molecolare:264.15Androgen receptor antagonist 12
CAS:Compound EF2 (Androgen receptor antagonist 12) is an orally active antagonist of the androgen receptor (AR) with an IC50 of 0.30 µM. It inhibits the transcriptional activity of mutant AR and the proliferation of AR-positive PCa (prostate cancer) cell lines. Additionally, Compound EF2 blocks the nuclear translocation of AR and suppresses tumor growth in the C4-2B xenograft mouse model. This compound is used for research in prostate cancer.Formula:C12H8F3N3O2Colore e forma:SolidPeso molecolare:283.2122-Hydroxy mifepristone
CAS:22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcohol metabolite that exhibits both anti-progestational and anti-glucocorticoid activities. This compound contains an alkyne group and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. Furthermore, 22-Hydroxy Mifepristone demonstrates a relative binding affinity of 48% to the human glucocorticoid receptor.Formula:C29H35NO3Colore e forma:SolidPeso molecolare:445.59LX1
CAS:LX1, an anti-prostate cancer compound, specifically targets the androgen receptor (AR), AR variants, and the steroidogenic enzyme AKR1C3. It inhibits AKR1C3's enzymatic function, decreases the conversion of androstenedione to testosterone, and reduces the expression of both AR and AR-V7, subsequently downregulating their target genes. Additionally, LX1 is effective in overcoming tumor cell resistance to Enzalutamide, and when combined with Enzalutamide, it further suppresses tumor growth.Formula:C22H15F6NO2Colore e forma:SolidPeso molecolare:439.35Androgen receptor degrader-5
CAS:Androgen receptor degrader-5 (compound 14k) demonstrates superior capabilities, specifically in androgen receptor degradation and antiproliferative activity, showcasing its promising properties.Formula:C29H25F4N5O2Colore e forma:SolidPeso molecolare:551.53
