Endocrinologia/Ormoni
Gli inibitori dell'endocrinologia/oromone sono composti che bloccano l'azione degli ormoni o interferiscono con le vie di segnalazione ormonale. Questi inibitori sono fondamentali per studiare la regolazione dei sistemi endocrini e per sviluppare trattamenti per malattie correlate agli ormoni, come il diabete, i disturbi della tiroide e i tumori ormono-dipendenti. Modulando l'attività ormonale, questi inibitori possono aiutare a chiarire le complesse interazioni all'interno del sistema endocrino. Presso CymitQuimica, offriamo un'ampia gamma di inibitori di alta qualità per endocrinologia/oromone per supportare le tue ricerche in endocrinologia, farmacologia e scienze mediche.
Sottocategorie di "Endocrinologia/Ormoni"
- Recettore degli androgeni(229 prodotti)
- Annessina A(16 prodotti)
- Aromatasi(22 prodotti)
- Recettore degli estrogeni/progestogeni(64 prodotti)
- GPR(1 prodotti)
- Recettore dei glucocorticoidi(165 prodotti)
- LHRH(2 prodotti)
- Recettore degli oppioidi(326 prodotti)
- Recettore della prostaglandina(122 prodotti)
- RAAS(86 prodotti)
- Riduttasi(51 prodotti)
- Somatostatina(57 prodotti)
- Recettore dell'ormone tiroideo (THR)(33 prodotti)
- Recettore della vasopressina(48 prodotti)
Mostrare 6 più sottocategorie
Trovati 3415 prodotti di "Endocrinologia/Ormoni"
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ERα degrader 12
ERα degrader12 (Compound RA3) is an estrogen receptor alpha (ERα) degrader with antitumor properties. It significantly suppresses tumor growth in a xenograft mouse model of breast cancer.Formula:C39H41NO9SColore e forma:SolidPeso molecolare:699.81Nurr1 agonist 5
Compound 5o, a Nurr1 agonist, exhibits neuroprotective properties as a transcription factor Nurr1 agonist, possessing a dissociation constant (Kd) of 0.5 μM andColore e forma:Odour SolidLO-4-25
LO-4-25 is a covalent degrader targeting the androgen receptor (AR) and its splice variant AR-V7. It covalently binds to the E3 ubiquitin ligase CUL4 DCAF16, facilitating the ubiquitination of both AR and AR-V7, which are then recognized and degraded by the proteasome, leading to reduced protein levels of AR and AR-V7 in cells. LO-4-25 is promising for research on androgen-independent prostate cancer.Colore e forma:Odour SolidUrotensin II (114-124), human TFA
Urotensin II (114-124), human TFA, is an 11-amino acid peptide and potent vasoconstrictor, acting as GPR14 agonist.Formula:C66H86F3N13O20S2Purezza:98%Colore e forma:SolidPeso molecolare:1502.59Zavacorilant
CAS:Zavacorilant is capable of modulating glucocorticoid receptor (GR).Formula:C25H26FN7O3S2Colore e forma:SolidPeso molecolare:555.65PROTAC AR Degrader-4 TFA
PROTAC AR Degrader-4: IAP ligand, linker, AR binder; it's a SNIPER that degrades AR non-genetically.Formula:C45H68F3N3O11Colore e forma:SolidPeso molecolare:884.03KOR agonist 4
KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.Formula:C21H25N3Colore e forma:SolidPeso molecolare:319.44HINT1-IN-1
HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).Formula:C23H24N8O5Colore e forma:SolidPeso molecolare:492.49PROTAC AR-V7 degrader-1
CAS:Potent, oral AR-V7 degrader (Compound 6); DC50: 0.32µM; targets AR-DBD via VHL E3; EC50: 0.88µM in 22Rv1 cells.Formula:C41H52N6O6S2Colore e forma:SolidPeso molecolare:789.02BI 653048 phosphate
CAS:BI 653048 phosphate is a selective and orally active agonist of nonsteroidal glucocorticoid (GC)(IC50 : 55 nM).Formula:C23H28F4N3O8PSPurezza:98%Colore e forma:SolidPeso molecolare:613.52Enclomiphene-d4
Enclomiphene-d4 is the deuterium-labeled analog of Enclomiphene. Enclomiphene functions as a potent and orally active estrogen receptor antagonist, exhibiting antiestrogenic properties.Colore e forma:Odour SolidCgp 29287
CAS:Cgp 29287 is a primate-specific renin inhibitor. It also has a prolonged duration of action.Formula:C72H110N20O15Colore e forma:SolidPeso molecolare:1495.77RLA-4842
RLA-4842: iron-based anti-androgen; inhibits mCRPC cell proliferation.Formula:C42H46F3N5O8SColore e forma:SolidPeso molecolare:837.94A7C-301
4A7C-301, a Nurr1 agonist, exhibits potent neuroprotective effects in vitro and markedly mitigates neuropathological abnormalities while enhancing motor andColore e forma:Odour SolidARCC-4
CAS:ARCC-4: A VHL-recruiting, low-nanomolar (DC50=5nM) AR degrader; outshines enzalutamide; degrades AR mutants resistant to therapy.Formula:C53H56F3N7O7S2Purezza:98%Colore e forma:SolidPeso molecolare:1024.18Parathyroid hormone (1-34) (rat)
CAS:Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats.Formula:C180H291N55O48S2Purezza:98%Colore e forma:SolidPeso molecolare:4057.74Biphalin TFA
CAS:Biphalin TFA is an opioid peptide analog that penetrates the blood-brain barrier (BBB) and encompasses two active enkephalin pharmacophores.Formula:C46H56N10O10·xC2HF3O2Purezza:98%Colore e forma:SolidPeso molecolare:909.00 (free base)Betamethasone acibutate
CAS:Betamethasone acibutate, a glucocorticoid, is derived from Betamethasone.Formula:C28H37FO7Purezza:98%Colore e forma:SolidPeso molecolare:504.59Remikiren
CAS:Remikiren is a highly specific renin inhibitor with oral activity for the treatment of hypertensio.Formula:C33H50N4O6SColore e forma:SolidPeso molecolare:630.842-Ethylhexyl trans-4-methoxycinnamate
CAS:2-Ethylhexyl trans-4-methoxycinnamate is a sunscreen agent.Formula:C18H26O3Purezza:98.92%Colore e forma:Pale Yellow LiquidPeso molecolare:290.4
