RAAS
Gli inibitori del sistema renina-angiotensina-aldosterone (RAAS) sono composti che prendono di mira la via del RAAS, nota principalmente per il suo ruolo nella regolazione della pressione sanguigna e dell'equilibrio dei fluidi, ma che influenza anche l'angiogenesi. La via del RAAS può contribuire allo sviluppo di nuovi vasi sanguigni nei tumori, supportandone così la crescita. Inibire i componenti del RAAS può quindi avere effetti anti-angiogenici, rendendo questi inibitori preziosi nel trattamento di alcuni tumori e disturbi vascolari. Presso CymitQuimica, offriamo una gamma di inibitori di alta qualità del RAAS per supportare la tua ricerca in biologia cardiovascolare, oncologia e angiogenesi.
Trovati 90 prodotti di "RAAS"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Pomisartan 2HCl
<p>Pomisartan 2HCl (BIBR363 2HCL) is a small molecule AT1R antagonist used to study heart failure and hypertension.</p>Formula:C31H32Cl2N4O2Purezza:99.88%Colore e forma:SoildPeso molecolare:563.52Zansecimab
CAS:<p>Zansecimab (LY-3127804) is a monoclonal antibody targeting angiopoietin 2 (Ang 2) for the study of cardiovascular and immune diseases.</p>Purezza:97.8% (SDS-PAGE); 99.7% (SEC-HPLC) - 97.8% (SDS-PAGE); 99.7% (SEC-HPLC)Colore e forma:LiquidLosartan potassium
CAS:Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to theFormula:C22H22ClKN6OPurezza:99.9% - >99.99%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:461.01Olmesartan Medoxomil
CAS:Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.Formula:C29H30N6O6Purezza:99.89% - 99.9%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:558.59Ref: TM-T1518
5mg35,00€10mg52,00€25mg60,00€50mg66,00€100mg87,00€200mg144,00€500mg274,00€1mL*10mM (DMSO)58,00€Losartan
CAS:Losartan (DuP-753) is an angiotensin II receptor antagonist.Formula:C22H23ClN6OPurezza:99.48% - >99.99%Colore e forma:Off White Solid PowderPeso molecolare:422.91CGP-42112 acetate
CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.Formula:C54H73N13O13Purezza:99.06% - 99.92%Colore e forma:SoildPeso molecolare:1112.24Ref: TM-T14939L
1mg87,00€5mg294,00€10mg424,00€25mg658,00€50mg884,00€100mg1.169,00€200mg1.586,00€1mL*10mM (DMSO)657,00€TRV055 acetate
TRV055 acetate is a ligand of angiotensin II type 1 receptor and stimulates cellular Gq-mediated signaling.Formula:C44H61N9O11Purezza:99.84%Colore e forma:SolidPeso molecolare:892.01Ref: TM-T40220L
1mg115,00€2mg162,00€5mg249,00€10mg369,00€25mg562,00€50mg787,00€100mg1.054,00€200mg1.406,00€1mL*10mM (DMSO)Prezzo su richiestaAlunacedase alfa
CAS:Alunacedase alfa (APN-01) is an angiotensin-converting enzyme 2 with antiviral activity.Purezza:99.1% (SDS-PAGE); 99.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 99.9% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:85.03 kDa[Sar1, Ile8]-Angiotensin II
CAS:[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.Formula:C46H73N13O10Purezza:98%Colore e forma:SolidPeso molecolare:968.15[Sar1, Ile8]-Angiotensin II acetate
'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.Formula:C48H77N13O12Purezza:99.36%Colore e forma:SolidPeso molecolare:1028.2Ref: TM-T7575L1
2mg35,00€5mg48,00€10mg64,00€25mg126,00€50mg202,00€100mg304,00€200mg439,00€1mL*10mM (DMSO)96,00€Handle region peptide, rat
CAS:Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.Formula:C54H101N15O12SPurezza:98%Colore e forma:SolidPeso molecolare:1184.54Azilsartan Medoxomil Potassium
CAS:Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.Formula:C30H23N4O8·KPurezza:99.99%Colore e forma:SolidPeso molecolare:606.62[Sar1, Ile8]-Angiotensin II TFA
[Sar1,Ile8]-Angiotensin II (TFA) contracts arteries and affects cell growth in vascular muscle.Formula:C48H74F3N13O12Purezza:98%Colore e forma:SolidPeso molecolare:1082.18Angiotensin II (1-4), human TFA
Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.Formula:C26H38F3N7O10Purezza:98%Colore e forma:SolidPeso molecolare:665.62Angiotensin II 5-valine
CAS:ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.Formula:C49H69N13O12Purezza:98%Colore e forma:SolidPeso molecolare:N/AAngiotensin amide
CAS:Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.Formula:C49H70N14O11Purezza:98%Colore e forma:SolidPeso molecolare:1031.17Aliskiren D6 Hydrochloride
CAS:Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).Formula:C30H54ClN3O6Purezza:98%Colore e forma:SolidPeso molecolare:594.26Brain Natriuretic Peptide (1-32), rat
CAS:Rat Brain Natriuretic Peptide (1-32) is a 32-amino-acid peptide from heart, released when ventricles stretch excessively.Formula:C146H239N47O44S3Purezza:98%Colore e forma:SolidPeso molecolare:3452.94Angiotensin II (5-8), human
CAS:Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin IIFormula:C26H36N6O5Purezza:98%Colore e forma:SolidPeso molecolare:512.6Angiotensin II (1-4), human
CAS:Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.Formula:C24H37N7O8Purezza:98%Colore e forma:SolidPeso molecolare:551.59Saralasin
CAS:Competitive non-selective angiotensin II antagonist.Formula:C42H65N13O10Purezza:98%Colore e forma:PowderPeso molecolare:912C-Type Natriuretic Peptide (1-53), human
CAS:CNP, from natriuretic family, first in pigs, now in other species, processes into CNP-22/CNP-53, similar to ANP/BNP, with varying potencies.Formula:C251H417N81O71S3Purezza:98%Colore e forma:SolidPeso molecolare:5801.77TRV056
CAS:TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.Formula:C52H74N14O13Colore e forma:SolidPeso molecolare:1103.249Aclerastide
CAS:Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.Formula:C42H64N12O11Colore e forma:SolidPeso molecolare:913.03Eprosartan
CAS:Eprosartan is a selective AT1 receptor blocker with IC50s of 9.2 nM (rat) and 3.9 nM (human), used for hypertension.Formula:C23H24N2O4SPurezza:99.99%Colore e forma:SolidPeso molecolare:424.51PRO20
<p>PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.</p>Colore e forma:Odour SolidTetrahydro Aldosterone
CAS:<p>Tetrahydro Aldosterone is a steroidal compound that inhibits the adrenal angiotensin II receptor, with an IC50 of 10 μM.</p>Formula:C21H32O5Colore e forma:SolidPeso molecolare:364.48Angiotensin II (3-8), human TFA
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.Formula:C42H55F3N8O10Purezza:98%Colore e forma:SolidPeso molecolare:888.93Renin FRET Substrate I
CAS:Renin FRET Substrate I, designed for human renin, contains angiotensinogen's N-terminal cleavage site.Formula:C90H120N22O16SPeso molecolare:1798.15BIBS 39
CAS:BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.Formula:C32H36N4O3Purezza:99.28%Colore e forma:SolidPeso molecolare:524.65A 779
CAS:A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.Formula:C39H60N12O11Purezza:98%Colore e forma:SolidPeso molecolare:872.97Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg
Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg is a fluorescent renin substrate based on the N-terminal tetrapeptide sequence of human angiotensinogen (hTDP).Formula:C129H179N37O24SPeso molecolare:2662.36444Chymase
CAS:Chymase is a proteolytic enzyme predominantly found in mast cells (MC), fibroblasts, and vascular endothelial cells. It is released into the extracellular matrix in response to inflammatory signals, tissue damage, and cellular stress. Chymase also plays a role in the generation of angiotensin II (Ang II), making it significant for cardiovascular disease research.Nesvacumab
CAS:Nesvacumab (REGN910) is a fully human monoclonal antibody targeting Angiopoietin 2 (Ang2), which can be used for studying advanced solid tumors.Purezza:98.7% (SDS-PAGE); 95.7% (SEC-HPLC) - 99.11% (SEC-HPLC)Colore e forma:LiquidValsartan Methyl Ester
CAS:<p>Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.</p>Formula:C25H31N5O3Purezza:99.54%Colore e forma:SolidPeso molecolare:449.55Losartan (D4 Carboxylic Acid)
CAS:Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.Formula:C22H21ClN6O2Purezza:98%Colore e forma:SolidPeso molecolare:440.92Olmesartan-d4
CAS:Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.Formula:C24H26N6O3Purezza:98%Colore e forma:SolidPeso molecolare:450.53Azilsartan-d5
CAS:Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.Formula:C25H20N4O5Purezza:98%Colore e forma:SolidPeso molecolare:461.48Angiotensin II (3-8), human
CAS:Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.Colore e forma:SolidValsartan-d9
CAS:Valsartan D9: deuterium-labeled, angiotensin II receptor antagonist, treats hypertension & heart failure.Formula:C24H29N5O3Purezza:98%Colore e forma:SolidPeso molecolare:444.57Angiogenin (108-122)
CAS:Angiogenin (108-122) peptide treats cancer, infectious, fibrotic, inflammatory, neurodegenerative, autoimmune, and heart diseases.Formula:C78H125N25O23Colore e forma:SolidPeso molecolare:1780.98PD 123319 ditrifluoroacetate
CAS:PD 123319 ditrifluoroacetate is a selective non-peptide AT2 receptor antagonist with IC50 of 34 nM.Formula:C35H34F6N4O7Purezza:98%Colore e forma:SolidPeso molecolare:736.66Candesartan-d4
CAS:Candesartan D4 is the deuterium labeled Candesartan. Candesartan is an antagonist of angiotensin II receptor.Formula:C24H20N6O3Purezza:98%Colore e forma:SolidPeso molecolare:444.48Angiotensin I/II (1-6)
CAS:Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide.Formula:C36H55N11O10Purezza:99.44%Colore e forma:SolidPeso molecolare:801.89Angiotensin 1/2 (5-7) acetate
Angiotensin 1/2 (5-7) acetate: a dipsogenic hormone peptide, sequence H2N-Ile-His-Pro-OH, from liver-produced angiotensinogen.Formula:C19H31N5O6Purezza:99.13%Colore e forma:SolidPeso molecolare:425.49Ref: TM-T22574L
1mg44,00€2mg55,00€5mg65,00€10mg95,00€25mg131,00€50mg190,00€100mg285,00€200mg429,00€500mg705,00€Olmesartan
CAS:Olmesartan (RNH 6270) is an Angiotensin II Type I receptor antagonist.Formula:C24H26N6O3Purezza:91.89% - 99.81%Colore e forma:White To Beige Solid SolidPeso molecolare:446.5Trans-Tranilast
CAS:Trans-Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It has been used for the treatment of allergic disorders such as atopic dermatitis.Formula:C18H17NO5Purezza:99.41% - ≥95%Colore e forma:SolidPeso molecolare:327.33Eprosartan Mesylate
CAS:Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.Formula:C23H24N2O4S·CH4O3SPurezza:99.72% - 99.93%Colore e forma:A White To Off- White PowderPeso molecolare:520.62Ref: TM-T2531
10mg48,00€25mg69,00€50mg85,00€100mg110,00€200mg170,00€500mg278,00€1mL*10mM (DMSO)48,00€Angiotensin III, human, mouse
CAS:Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA))(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).Formula:C46H66N12O9Purezza:98.44%Colore e forma:SolidPeso molecolare:931.09Angiotensin II 5-valine TFA
Angiotensin II 5-valine TFA is an agonist of angiotensin receptor.Formula:C51H70F3N13O14Purezza:99.69%Colore e forma:SolidPeso molecolare:1146.18
![[Sar1, Ile8]-Angiotensin II](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT7575.webp&w=3840&q=75)
![[Sar1, Ile8]-Angiotensin II acetate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT7575L1.webp&w=3840&q=75)
