Recettore degli androgeni
Il recettore degli androgeni (AR) è un recettore ormonale nucleare che viene attivato dal legame con gli androgeni, come il testosterone e il diidrotestosterone. Questo recettore svolge un ruolo cruciale nello sviluppo e nel mantenimento delle caratteristiche maschili, nonché nella regolazione di diversi processi fisiologici, tra cui la crescita muscolare, la libido e la densità ossea. Gli inibitori del recettore degli androgeni sono ampiamente studiati nel contesto del cancro alla prostata, dove la segnalazione dell'AR è spesso sovraregolata. Presso CymitQuimica, offriamo una gamma di modulatori del recettore degli androgeni di alta qualità per supportare la tua ricerca in endocrinologia, biologia del cancro e regolazione ormonale.
Trovati 229 prodotti di "Recettore degli androgeni"
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AR antagonist 6
CAS:<p>AR antagonist 6 (compound 6i), a diphenyl ether androgen receptor (AR) antagonist, binds to the AR with an affinity of 120 nM. It demonstrates low toxicity and effective in vitro activity in the golden Syrian hamster ear model. [19] [1]</p>Formula:C16H12F3NO2Colore e forma:SolidPeso molecolare:307.27Procymidone
CAS:Procymidone is a broad-spectrum fungicide that inhibits fungal glycerol triester synthesis, thereby disrupting hyphal growth. androgen receptor (AR) antagonistFormula:C13H11Cl2NO2Purezza:99.86%Colore e forma:Colorless SolidPeso molecolare:284.14JNJ-37654032
CAS:JNJ-37654032: orally active, nonsteroidal SARM. Mixed AR agonist/antagonist. Selective for muscle, grows levator ani, max at 3mg/kg, ED(50) 0.8mg/kg.Formula:C11H7Cl2F3N2OColore e forma:SolidPeso molecolare:311.09Androgen receptor antagonist 4
CAS:Compound AT2 is an AR inhibitor with anticancer effects, blocking DHT action and AR nuclear translocation (IC50=0.15μM).Formula:C22H18ClNColore e forma:SolidPeso molecolare:331.84Chlormadinone (free base)
CAS:Chlormadinone: synthetic hormone, treats BPH and PCOS, blocks androgen/estrogen, boosts bone cell growth.Formula:C21H27ClO3Colore e forma:SolidPeso molecolare:362.89Bifluranol
CAS:Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostaticFormula:C17H18F2O2Purezza:99.86%Colore e forma:SolidPeso molecolare:292.32Gumelutamide
CAS:Gumelutamide, a tetrahydropyridopyrimidine compound, functions as both an antiandrogen and an antineoplastic agent by acting as an androgen antagonist.Formula:C22H21ClN6OColore e forma:SolidPeso molecolare:420.89AZD3514
CAS:<p>AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.</p>Formula:C25H32F3N7O2Purezza:98.09%Colore e forma:SolidPeso molecolare:519.56Honokiol DCA
CAS:Honokiol DCA inhibits DRP1, enhances respiration via mitochondrial repair, and is active against Vemurafenib-resistant melanoma.Formula:C22H18Cl4O4Colore e forma:SolidPeso molecolare:488.19Prochloraz
CAS:Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.Formula:C15H16Cl3N3O2Purezza:99.75% - 99.79%Colore e forma:Colorless SolidPeso molecolare:376.67LG-121071
CAS:LG-121071: oral SARM, high-affinity AR full agonist, Ki=17 nM.Formula:C15H15F3N2OPurezza:98%Colore e forma:SolidPeso molecolare:296.29AR antagonist 5
CAS:<p>Compound 30a, known as AR Antagonist 5, is a selective androgen receptor (AR) antagonist that demonstrates an IC 50 value of 134.8 nM. It exhibits favorable pharmacokinetic properties, characterized by high skin exposure and low plasma exposure [1].</p>Formula:C23H21F3N6O2Colore e forma:SolidPeso molecolare:470.45(R)-Bicalutamide
CAS:(R)-Bicalutamide, an AR antagonist with antitumor properties, is crucial in prostate cancer research.Formula:C18H14F4N2O4SColore e forma:SolidPeso molecolare:430.37AR antagonist 2
CAS:AR antagonist 2 (compound 58) is a potent inhibitor of the androgen receptor (AR) (IC50: 0.95 μM).Formula:C22H17ClFN5O2SColore e forma:SolidPeso molecolare:469.92Bromopropylate
CAS:Bromopropylate is an insecticide. Bromopropylate is the active substance in fumigant strips for mites.Formula:C17H16Br2O3Purezza:98%Colore e forma:White Crystalline Solid Yellowish CrystalsPeso molecolare:428.11S-40503
CAS:S-40503 is an investigational selective androgen receptor modulator (SARM).Formula:C15H23N3O3Colore e forma:SolidPeso molecolare:293.36Ralaniten
CAS:Ralaniten (EPI-002), a potent AR-NTD antagonist, inhibits AR with IC50 of 7.4 μM, for CRPC study.Formula:C21H27ClO5Purezza:99.96%Colore e forma:SolidPeso molecolare:394.89Androgen receptor antagonist 1
CAS:Androgen receptor antagonist 1, an oral full AR antagonist (IC50 59 nM), for PROTAC synthesis, reducing AR protein by 24–47% in LNCaP cells at 1–10 μM.Formula:C21H25ClN4O3Purezza:99.054%Colore e forma:SolidPeso molecolare:416.9RU 58642
CAS:RU 58642 is an effective systemic antiandrogen for androgen-dependent disorders.Formula:C15H11F3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:336.27Cyprodinil
CAS:Cyprodinil is a fungicide blocking methionine synthesis in fungi and hinders B. cinerea, P. herpotrichoides, H. oryzae growth; it's also an AR agonist.Formula:C14H15N3Colore e forma:SolidPeso molecolare:225.29
