Enzima
Gli inibitori enzimatici sono molecole che si legano agli enzimi e ne diminuiscono l'attività. Questi inibitori sono ampiamente utilizzati nella ricerca per studiare la cinetica enzimatica, la regolazione e il ruolo di specifici enzimi nelle vie metaboliche. Gli inibitori enzimatici sono anche fondamentali nello sviluppo di farmaci, poiché molti agenti terapeutici agiscono inibendo enzimi coinvolti in processi patologici. Mirando agli enzimi, questi inibitori possono modulare le vie biochimiche e offrire potenziali trattamenti per varie malattie. Presso CymitQuimica, offriamo una vasta selezione di inibitori enzimatici di alta qualità per supportare le tue ricerche in biochimica, farmacologia e scoperta di farmaci.
Sottocategorie di "Enzima"
- Anidrasi carbonica(192 prodotti)
- Idrossilasi(35 prodotti)
- MPO(2 prodotti)
- Riduttasi(50 prodotti)
- Tirosinasi(71 prodotti)
Trovati 3613 prodotti di "Enzima"
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DOTA-XYIMSR-01
CAS:DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.Formula:C61H88N16O22S2Colore e forma:SolidPeso molecolare:1461.57CAIX/CAXII-IN-4
<p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>Formula:C23H21N5O3SColore e forma:SolidPeso molecolare:447.51TPH1-IN-1
TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.Formula:C21H18N6O4SColore e forma:SolidPeso molecolare:450.47Tyrosinase-IN-32
<p>Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.</p>Formula:C15H19NO3Colore e forma:SolidPeso molecolare:261.32hCA/VEGFR-2-IN-2
Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII andFormula:C23H26N6O5SPurezza:98%Colore e forma:SolidPeso molecolare:498.552-Methoxy-4-propylphenol
CAS:<p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>Formula:C10H14O2Colore e forma:SolidPeso molecolare:166.22CAIX Inhibitor S4
CAS:<p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>Formula:C15H17N3O4SPurezza:99.07%Colore e forma:SolidPeso molecolare:335.38Peroxidase, from horseradish, approx. 200 U/mg
CAS:Purezza:≥ 150U/mgColore e forma:Beige to light-brown, reddish brown or dark brown lyophilised powderPeso molecolare:-Proteinase K
CAS:Purezza:≥ 30units/mg (pH 7.5, 37°C, dried basis)Colore e forma:White or almost white lyophilized powderPeso molecolare:-β-Amylase, from soy
CAS:Purezza:≥ 10.0units/mgColore e forma:White to off-white powderPeso molecolare:-Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFormula:C47H64N14O10Colore e forma:SolidPeso molecolare:985.1hCAII-IN-6
"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."Formula:C20H25N3O4SColore e forma:SolidPeso molecolare:403.5IOX2-NH2-1
CAS:<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Formula:C19H17N3O5Purezza:98.77% - 99.91%Colore e forma:SoildPeso molecolare:367.36hCAII-IN-7
hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.Formula:C20H25N3O4SColore e forma:SolidPeso molecolare:403.5DPP IV/hCA II-IN-1
CAS:<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Formula:C17H20N2O5SColore e forma:SolidPeso molecolare:364.42TPT-004
TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuatingColore e forma:Odour SolidTSPO/Carbonic Anhydrase Modulator 1
TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.Formula:C35H51N3O3Colore e forma:SolidPeso molecolare:561.798Chlorothiazide
CAS:Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.Formula:C7H6ClN3O4S2Purezza:98.46% - 98.91%Colore e forma:Crystals Physical Description Crystals; White Powder (Ntp 1992)Peso molecolare:295.72Phenylsulfamide
CAS:<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Formula:C6H8N2O2SColore e forma:SolidPeso molecolare:172.2Calmodulin-dependent Protein Kinase II fragment 290-309
CAS:Formula:C103H185N31O24SPeso molecolare:2273.83Acesulfame
CAS:Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.Formula:C4H5NO4SColore e forma:SolidPeso molecolare:163.15Pyrocatechol
CAS:Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.Formula:C6H6O2Purezza:99.96%Colore e forma:SolidPeso molecolare:110.11Anhydrotetracycline hydrochloride
CAS:Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.Formula:C22H23ClN2O7Purezza:98% - 98.90%Colore e forma:SolidPeso molecolare:462.88Xanthine Oxidase, ammonium sulfate suspension
CAS:Colore e forma:Faint brown to dark brown suspensionhCA/Wnt/β-catenin-IN-1
hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8Colore e forma:Odour SolidCarbonic anhydrase inhibitor 29
Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.Colore e forma:Odour SolidTyrosinase-IN-34
Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.Formula:C19H14BrClN4OColore e forma:SolidPeso molecolare:429.7CAIX/CAXII-IN-3
CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.Colore e forma:Odour SolidTyrosinase-IN-36
Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.Colore e forma:Odour SolidPeroxidase
CAS:Purezza:≥ 85units/mg (dry basis)Colore e forma:Beige to light-brown, reddish brown or dark brown lyophilised powderPeso molecolare:-
![Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76347.webp&w=3840&q=75)
