Idrossilasi
Le idrossilasi sono una classe di enzimi che catalizzano l'idrossilazione dei substrati, spesso aggiungendo gruppi idrossilici (-OH) a posizioni specifiche all'interno delle molecole. Questi enzimi sono coinvolti in una vasta gamma di percorsi biochimici, inclusa la sintesi di ormoni, i processi di detossificazione e il metabolismo dei farmaci. Gli inibitori e gli attivatori delle idrossilasi sono strumenti preziosi nella ricerca sui disturbi metabolici, sul metabolismo dei farmaci e sulla regolazione ormonale. Presso CymitQuimica, offriamo una selezione di reagenti per idrossilasi di alta qualità per supportare la tua ricerca in biochimica, farmacologia e regolazione metabolica.
Trovati 35 prodotti di "Idrossilasi"
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Fenclonine
CAS:Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.Formula:C9H10ClNO2Purezza:98.81% - >99.99%Colore e forma:Crystals From Methanol White SolidPeso molecolare:199.63ACT-678689
CAS:<p>ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].</p>Formula:C23H22ClFN6O4S2Purezza:99.46%Colore e forma:SolidPeso molecolare:565.04Telotristat ethyl
CAS:Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.Formula:C27H26ClF3N6O3Purezza:98% - 99.89%Colore e forma:White SolidPeso molecolare:574.98p-Ethynylphenylalanine hydrochloride
CAS:p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1].Formula:C11H12ClNO2Purezza:99.03%Colore e forma:SolidPeso molecolare:225.67Butobendine
CAS:Butobendine is a compound derived from gallic acid and exhibits significant antiarrhythmic activity.Formula:C32H48N2O10Peso molecolare:620.73IOX2-NH2-1
CAS:<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Formula:C19H17N3O5Purezza:98.77% - 99.91%Colore e forma:SoildPeso molecolare:367.36TPH1-IN-1
TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.Formula:C21H18N6O4SColore e forma:SolidPeso molecolare:450.47TPT-004
TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuatingColore e forma:Odour SolidGSK180
CAS:GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism.Formula:C10H7Cl2NO4Colore e forma:SolidPeso molecolare:276.07Cuprizone
CAS:Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.Formula:C14H22N4O2Purezza:≥98%Colore e forma:SolidPeso molecolare:278.35FG-2216
CAS:FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.Formula:C12H9ClN2O4Purezza:97.1% - >99.99%Colore e forma:SolidPeso molecolare:280.66Ro 61-8048
CAS:Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.Formula:C17H15N3O6S2Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:421.45Telotristat
CAS:<p>Telotristat, active metabolite of LX1606, is an oral tryptophan hydroxylase inhibitor with potential antiserotonergic effects.</p>Formula:C25H22ClF3N6O3Purezza:99.70%Colore e forma:SolidPeso molecolare:546.93p-Fluoro-L-phenylalanine
CAS:p-Fluoro-L-phenylalanine: TH substrate, studies enzyme regulation, binds E. coli L-leucine receptor, KD 0.26μM.Formula:C9H10FNO2Purezza:99.63%Colore e forma:White To Off-White PowderPeso molecolare:183.18Fenclonine hydrochloride
CAS:Fenclonine hydrochloride is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.Formula:C9H11Cl2NO2Colore e forma:SolidPeso molecolare:236.095Telotristat Etiprate
CAS:Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.Formula:C27H26ClF3N6O3·C9H9NO3Purezza:99.21% - 99.83%Colore e forma:White SolidPeso molecolare:754.15Tetrahydropapaverine hydrochloride
CAS:<p>Tetrahydropapaverine hydrochloride (Norlaudanosine HCl) , an analogue of salsolinol and tetrahydropapaveroline, has neurotoxicity on dopamine neurons.</p>Formula:C20H26ClNO4Purezza:99.08%Colore e forma:White Crystal PowderPeso molecolare:379.878Mildronate
CAS:Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitineFormula:C6H14N2O2Purezza:99.94%Colore e forma:White Crystalline PowderPeso molecolare:146.19TETRAHYDROPIPERINE
CAS:Tetrahydropiperine (Cosmoperine) is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.Formula:C17H23NO3Purezza:98.04% - 99.61%Colore e forma:Off-White Low Melting Solid With Characteristic OdourPeso molecolare:289.37Nepicastat
CAS:<p>Nepicastat (SYN117) is a potent, BBB-permeable, selective DBH inhibitor with IC50s of 8.5/9 nM in bovine/human.</p>Formula:C14H15F2N3SColore e forma:SolidPeso molecolare:295.35Guanoclor
CAS:<p>Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.</p>Formula:C9H12Cl2N4OPurezza:98.79%Colore e forma:SolidPeso molecolare:263.12Nepicastat hydrochloride
CAS:<p>Nepicastat hydrochloride (RS-25560-197 hydrochloride) is a selective, orally active, dopamine-beta-hydroxylase inhibitor that crosses the blood-brain barrier.</p>Formula:C14H15F2N3S·HClPurezza:98.35% - 99.74%Colore e forma:SolidPeso molecolare:331.81LP-533401
CAS:LP-533401 is an inhibitor of Tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut.Formula:C27H22F4N4O3Purezza:98%Colore e forma:SolidPeso molecolare:526.48Phenylthiazolylthiourea
CAS:Phenylthiazolylthiourea ia a dopamine-beta-hydroxylase inhibitor.Formula:C10H9N3S2Colore e forma:SolidPeso molecolare:235.33Telotristat besilate
CAS:Telotristat besilate is an inhibitor of tryptophan hydroxylase.Formula:C31H28ClF3N6O6SPurezza:98%Colore e forma:SolidPeso molecolare:705.11(R)-Nepicastat HCl
CAS:<p>(R)-Nepicastat HCl (RS-25560-198 HCl), R-enantiomer, inhibits bovine/human dopamine-β-hydroxylase (IC50: 25.1/18.3 nM); not affecting other enzymes/receptors.</p>Formula:C14H15F2N3S·HClPurezza:98%Colore e forma:SolidPeso molecolare:331.81Fenprinast
CAS:Fenprinast is a tryptophan-like bronchodilator utilized in the study of allergic and exercise-induced asthma. It exhibits oral activity.Formula:C16H16ClN5OPeso molecolare:329.783-Allylphenol
CAS:3-Allylphenol is an inhibitor of dopamine β-hydroxylase (DBH; Ki = 12 mM).Formula:C9H10OColore e forma:SolidPeso molecolare:134.18JM6
CAS:JM6 is a weak kynurenine 3-monooxygenase (KMO) inhibitor that acts on mouse KMO (IC50: 19.85 μM). JM6 can be used to study Alzheimer's disease.Formula:C23H26N4O6S2Colore e forma:SolidPeso molecolare:518.61SU 10603
CAS:SU 10603 is a specific inhibitor of 17α-hydroxylase (also known as CYP17A1 and P450c17) used to study steroid hormone synthesis.Formula:C15H12ClNOPurezza:99.93% - 99.96%Colore e forma:SolidPeso molecolare:257.72Bupicomide
CAS:Bupicomide is a dopamine β-hydroxylase inhibitor with antihypertensive and vasodilatory activity and may be used in the study of hypertension.Formula:C10H14N2OPurezza:99.84% - >99.99%Colore e forma:SolidPeso molecolare:178.23LX-1031
CAS:LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.Formula:C28H25F3N4O4Purezza:97.123% - 98.97%Colore e forma:SolidPeso molecolare:538.52Diethyl-pythiDC
CAS:<p>Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor.</p>Formula:C14H14N2O4SPurezza:99.98%Colore e forma:SolidPeso molecolare:306.34p-Ethynylphenylalanine
CAS:p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki ofFormula:C11H11NO2Purezza:99.44%Colore e forma:SolidPeso molecolare:189.21GSK 366
CAS:GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).Formula:C17H16ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:361.78
