NF-κB
Il fattore nucleare kappa-light-chain-enhancer delle cellule B attivate (NF-κB) è un fattore di trascrizione che regola l'espressione di geni coinvolti nelle risposte immunitarie, nell'infiammazione, nella sopravvivenza cellulare e nella proliferazione. NF-κB viene attivato in risposta a vari stimoli, tra cui citochine, agenti patogeni e segnali di stress. La disregolazione della segnalazione di NF-κB è associata a malattie infiammatorie croniche, cancro e disturbi autoimmuni. Presso CymitQuimica, offriamo una selezione completa di modulatori della via NF-κB per supportare la tua ricerca su infiammazione, oncologia e regolazione immunitaria.
Trovati 399 prodotti di "NF-κB"
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PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purezza:98.82%Colore e forma:SolidPeso molecolare:394.47SM-7368
CAS:The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.Formula:C10H5ClN4O5SPurezza:99.64%Colore e forma:SolidPeso molecolare:328.69Ref: TM-T22115
5mg44,00€10mg71,00€25mg128,00€50mg178,00€100mg268,00€200mg389,00€1mL*10mM (DMSO)52,00€IRAK-1-4 Inhibitor I
CAS:IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.
Formula:C20H21N5O4Purezza:98% - 99.89%Colore e forma:SolidPeso molecolare:395.41Zimlovisertib
CAS:Zimlovisertib (PF-06650833) is an effective, selective and orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4).Formula:C18H20FN3O4Purezza:98.21%Colore e forma:SolidPeso molecolare:361.3711-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Formula:C30H46O4Purezza:99.68%Colore e forma:SolidPeso molecolare:470.68Ref: TM-TN1182
1mg60,00€5mg137,00€10mg210,00€25mg356,00€50mg525,00€100mg750,00€1mL*10mM (DMSO)140,00€Maslinic acid
CAS:Maslinic acid (Crategolic acid) is a DNA polymerase B inhibitor.Formula:C30H48O4Purezza:98.1% - 99.98%Colore e forma:SolidPeso molecolare:472.70Malachite green oxalate
CAS:Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.Formula:C23H25N2·C2HO4C2H2O4Colore e forma:Dark Green Crystals With A Metallic LusterPeso molecolare:463.51Sarsasapogenin
CAS:Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin.Formula:C27H44O3Purezza:90% - 99.73%Colore e forma:White Or Off-Withe PowderPeso molecolare:416.64Obtusifolin
CAS:Obtusifolin is an antioxidant that combats diabetes, bone-resorption, diabetic retinopathy, pain, and cognitive decline.Formula:C16H12O5Purezza:99.78% - 99.99%Colore e forma:SolidPeso molecolare:284.26Ref: TM-T4S0969
1mg66,00€5mg177,00€10mg264,00€25mg447,00€50mg623,00€100mg883,00€1mL*10mM (DMSO)177,00€Neferine
CAS:Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formula:C38H44N2O6Purezza:98.81% - 99.65%Colore e forma:SolidPeso molecolare:624.77Gossypin
CAS:Gossypin exhibits multiple medicinal properties and inhibits NF-kappaB, reducing inflammation, cancer growth, and angiogenesis.Formula:C21H20O13Purezza:97.57% - 98.97%Colore e forma:SolidPeso molecolare:480.38Aconine
CAS:1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props.Formula:C25H41NO9Purezza:99.61% - 99.93%Colore e forma:SolidPeso molecolare:499.59Madecassic acid
CAS:Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Formula:C30H48O6Purezza:98.80% - 99.69%Colore e forma:SolidPeso molecolare:504.70Delanzomib
CAS:Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like activity with minimal effect on other activities.Formula:C21H28BN3O5Purezza:95.52% - 99.46%Colore e forma:SolidPeso molecolare:413.28Ref: TM-T6027
1mg46,00€5mg96,00€10mg140,00€25mg274,00€50mg439,00€100mg660,00€200mg917,00€1mL*10mM (DMSO)95,00€Deoxyelephantopin
CAS:Deoxyelephantopin: anti-inflammatory, hepatoprotective, wound healing, antitumor; blocks NF-κB, MAPK, PI3K/Akt, β-catenin pathways.Formula:C19H20O6Purezza:99.6% - 99.71%Colore e forma:SolidPeso molecolare:344.36Aristolochic acid A
CAS:Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort family of plants.Formula:C17H11NO7Purezza:99.85% - 99.97%Colore e forma:Yellow PowderPeso molecolare:341.27Indole-3-carbinol
CAS:Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinaseFormula:C9H9NOPurezza:98.59% - >99.99%Colore e forma:SolidPeso molecolare:147.17Sodium Aescinate
CAS:Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii.Formula:C54H83NaO23Purezza:95.17%Colore e forma:SolidPeso molecolare:1123.21Specnuezhenide
CAS:Specnuezhenide (Nuezhenide) is isolated from the fruit of Ligustrum lucidum. It inhibits NF-κB and wnt/β-catenin signaling.Cost-effective and quality-assured.Formula:C31H42O17Purezza:98% - 99.93%Colore e forma:SolidPeso molecolare:686.66Ref: TM-T3803
2mg34,00€5mg50,00€10mg80,00€25mg152,00€50mg219,00€100mg319,00€200mg474,00€1mL*10mM (DMSO)77,00€GSK-872
CAS:GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity and inhibits kinase activity.
Formula:C19H17N3O2S2Purezza:99.87% - 99.94%Colore e forma:SolidPeso molecolare:383.49
