NF-κB
Il fattore nucleare kappa-light-chain-enhancer delle cellule B attivate (NF-κB) è un fattore di trascrizione che regola l'espressione di geni coinvolti nelle risposte immunitarie, nell'infiammazione, nella sopravvivenza cellulare e nella proliferazione. NF-κB viene attivato in risposta a vari stimoli, tra cui citochine, agenti patogeni e segnali di stress. La disregolazione della segnalazione di NF-κB è associata a malattie infiammatorie croniche, cancro e disturbi autoimmuni. Presso CymitQuimica, offriamo una selezione completa di modulatori della via NF-κB per supportare la tua ricerca su infiammazione, oncologia e regolazione immunitaria.
Trovati 407 prodotti di "NF-κB"
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ETHYL CAFFEATE
CAS:Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.Formula:C11H12O4Purezza:97.79%Colore e forma:SolidPeso molecolare:208.21Dehydroevodiamine
CAS:Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressantFormula:C19H15N3OPurezza:99.54%Colore e forma:SolidPeso molecolare:301.34Ethacrynic acid
CAS:Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。Formula:C13H12Cl2O4Purezza:98.61% - 99.85%Colore e forma:Crystals Physical Description White Solid (Ntp 1992)Peso molecolare:303.14Isoquercetin
CAS:1.Formula:C21H20O12Purezza:98.08% - 99.76%Colore e forma:SolidPeso molecolare:464.38Ref: TM-T5S0754
5mg46,00€10mg58,00€25mg92,00€50mg137,00€100mg200,00€200mg295,00€1mL*10mM (DMSO)49,00€Micheliolide
CAS:Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.Formula:C15H20O3Purezza:98% - 99.37%Colore e forma:SolidPeso molecolare:248.32Ref: TM-T5688
1mg47,00€5mg119,00€10mg187,00€25mg316,00€50mg472,00€100mg658,00€500mg1.378,00€1mL*10mM (DMSO)131,00€Licochalcone D
CAS:Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.Formula:C21H22O5Purezza:99.03% - 99.9%Colore e forma:SolidPeso molecolare:354.4Ginsenoside Rk3
CAS:Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.Formula:C36H60O8Purezza:99.88%Colore e forma:SolidPeso molecolare:620.86Ref: TM-T6S1495
1mg85,00€5mg172,00€10mg255,00€25mg426,00€50mg630,00€100mg898,00€1mL*10mM (DMSO)283,00€Rhoifolin
CAS:Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Formula:C27H30O14Purezza:98.11% - 98.58%Colore e forma:SolidPeso molecolare:578.52Muscone
CAS:Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.Formula:C16H30OPurezza:98.97% - ≥98%Colore e forma:Colourless Liquid LiquidPeso molecolare:238.41Ginsenoside Rd
CAS:Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.Formula:C48H82O18Purezza:99.13% - 99.92%Colore e forma:SolidPeso molecolare:947.15Ref: TM-T2878
1mg37,00€5mg71,00€10mg99,00€25mg170,00€50mg260,00€100mg394,00€200mg570,00€1mL*10mM (DMSO)124,00€WITHAFERIN A
CAS:WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/Formula:C28H38O6Purezza:97.41% - 99.99%Colore e forma:SolidPeso molecolare:470.60Ref: TM-T5687
1mg85,00€5mg265,00€10mg393,00€25mg653,00€50mg929,00€100mg1.254,00€500mg2.517,00€1mL*10mM (DMSO)304,00€GSK583
CAS:GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM).Formula:C20H19FN4O2SPurezza:98.68% - 99.81%Colore e forma:SolidPeso molecolare:398.45Ref: TM-T3537
1mg49,00€2mg69,00€5mg92,00€10mg127,00€25mg216,00€50mg303,00€100mg416,00€200mg605,00€1mL*10mM (DMSO)97,00€IRAK inhibitor 6
CAS:IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).Formula:C20H20N4O3SPurezza:99.44%Colore e forma:SolidPeso molecolare:396.462-Hydroxychalcone
CAS:2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.Formula:C15H12O2Purezza:99.6%Colore e forma:SolidPeso molecolare:224.25anemarsaponin B
CAS:Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activityFormula:C45H74O18Purezza:99.06% - 99.11%Colore e forma:SolidPeso molecolare:903.0620(S)-Ginsenoside Rg3
CAS:20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.Formula:C42H72O13Purezza:98.11% - 99.93%Colore e forma:SolidPeso molecolare:785.012,5-Dihydroxyacetophenone
CAS:2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.Formula:C8H8O3Purezza:99.75%Colore e forma:Yellow PowderPeso molecolare:152.15Pyrrolidinedithiocarbamate ammonium
CAS:Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxideFormula:C5H12N2S2Purezza:98% - >99.99%Colore e forma:Off-White To Pale Yellow CrystalsPeso molecolare:164.29ISOGINKGETIN
CAS:ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Formula:C32H22O10Purezza:98% - 99.75%Colore e forma:SolidPeso molecolare:566.51Necrostatin-34
CAS:Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying aFormula:C18H16N4O2S2Purezza:98.66% - 98.8%Colore e forma:SolidPeso molecolare:384.48Ref: TM-T9095
1mg52,00€5mg116,00€10mg170,00€25mg305,00€50mg442,00€100mg615,00€200mg832,00€1mL*10mM (DMSO)135,00€
