NF-κB
Il fattore nucleare kappa-light-chain-enhancer delle cellule B attivate (NF-κB) è un fattore di trascrizione che regola l'espressione di geni coinvolti nelle risposte immunitarie, nell'infiammazione, nella sopravvivenza cellulare e nella proliferazione. NF-κB viene attivato in risposta a vari stimoli, tra cui citochine, agenti patogeni e segnali di stress. La disregolazione della segnalazione di NF-κB è associata a malattie infiammatorie croniche, cancro e disturbi autoimmuni. Presso CymitQuimica, offriamo una selezione completa di modulatori della via NF-κB per supportare la tua ricerca su infiammazione, oncologia e regolazione immunitaria.
Trovati 407 prodotti di "NF-κB"
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Ginsenoside Rg1
CAS:Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng).Formula:C42H72O14Purezza:99% - 99.92%Colore e forma:White Crystalline PowderPeso molecolare:801.01CBL0137 hydrochloride
CAS:CBL0137 hydrochloride (Curaxin-137 hydrochloride) is an inhibitor of the histone chaperone FACT, which also activates p53 and inhibits NF-κB.Cost-effective and quality-assured.Formula:C21H25ClN2O2Purezza:99.35% - 99.86%Colore e forma:SolidPeso molecolare:372.88Kaempferol-3-O-glucorhamnoside
CAS:Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside), a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via MAPKFormula:C27H30O15Purezza:96.96% - 98.17%Colore e forma:SolidPeso molecolare:594.5Ref: TM-T5S0089
1mg48,00€5mg92,00€10mg136,00€25mg215,00€50mg323,00€100mg469,00€200mg647,00€1mL*10mM (DMSO)122,00€Saikosaponin D
CAS:Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.Formula:C42H68O13Purezza:98.34% - 99.73%Colore e forma:White PowderPeso molecolare:780.98IMD-0354
CAS:IMD-0354 (IKK2 Inhibitor V) is an IKKβ inhibitor and inhibits IκBα phosphorylation in NF-κB pathway.Formula:C15H8ClF6NO2Purezza:99.65% - 99.98%Colore e forma:SolidPeso molecolare:383.67Ref: TM-T6141
2mg46,00€5mg63,00€10mg87,00€25mg155,00€50mg210,00€100mg294,00€500mg713,00€1mL*10mM (DMSO)65,00€Phellodendrine
CAS:Phellodendrine may treat nephritis by blocking macrophage and T cell activity in glomeruli.Formula:C20H24NO4Purezza:98.7% - 99.94%Colore e forma:SolidPeso molecolare:342.41Ref: TM-T6S0781
2mg43,00€5mg59,00€10mg85,00€25mg120,00€50mg170,00€100mg253,00€200mg375,00€1mL*10mM (DMSO)77,00€Muscone
CAS:Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.Formula:C16H30OPurezza:98.97% - ≥98%Colore e forma:Colourless Liquid LiquidPeso molecolare:238.41Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formula:C20H18O11Purezza:97.02% - 99.94%Colore e forma:White PowderPeso molecolare:434.35Ref: TM-T6S0117
1mg58,00€5mg97,00€10mg160,00€25mg283,00€50mg418,00€100mg615,00€200mg878,00€1mL*10mM (DMSO)111,00€BOT-64
CAS:BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathioleFormula:C15H15NO2SPurezza:99.73%Colore e forma:SolidPeso molecolare:273.35Ref: TM-T8705
1mg50,00€5mg110,00€10mg170,00€25mg323,00€50mg494,00€100mg665,00€200mg893,00€1mL*10mM (DMSO)102,00€Flaconitine
CAS:Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.
Formula:C36H49NO12Purezza:98% - 99.84%Colore e forma:SolidPeso molecolare:687.77Sulfuretin
CAS:Sulfuretin protects HepG2 cells from oxidative damage by scavenging ROS and activating HO-1 via Nrf2/ARE and JNK/ERK pathways.
Formula:C15H10O5Purezza:98.91% - 99.86%Colore e forma:SolidPeso molecolare:270.24BEC hydrochloride
CAS:BEC hydrochloride (BEC HCl) is a competitive arginase inhibitor, which bind slowly. Ki of BEC HCl is 0.31 μM (pH7.5) for Arginase II.Formula:C5H12BNO4S·ClHPurezza:98.65% - 99.28%Colore e forma:SolidPeso molecolare:229.49Ref: TM-T6779
1mg39,00€5mg88,00€10mg153,00€25mg283,00€50mg464,00€100mg663,00€200mg919,00€1mL*10mM (DMSO)88,00€3'-Sialyllactose
CAS:3'-Sialyllactose (3'-SL), a prebiotic, supports immunity, reduces inflammation and arthritis, and is low-toxicity for research.Formula:C23H39NO19Colore e forma:SolidPeso molecolare:633.55EUK-134
CAS:EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.Formula:C18H18ClMnN2O4Purezza:98.39%Colore e forma:SolidPeso molecolare:416.74Morusin
CAS:Morusin shows anti-tumor, antioxidant, and anti-inflammatory properties by inhibiting STAT3, NFκB, and inducing apoptosis.Formula:C25H24O6Purezza:98.68% - 99.8%Colore e forma:SolidPeso molecolare:420.45QNZ
CAS:QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Formula:C22H20N4OPurezza:99.17% - 99.18%Colore e forma:White SolidPeso molecolare:356.42Ref: TM-T6204
1mg43,00€2mg57,00€5mg93,00€10mg140,00€25mg188,00€50mg329,00€100mg490,00€200mg710,00€1mL*10mM (DMSO)93,00€BMS-345541
CAS:BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.Formula:C14H17N5Purezza:99.36% - 99.74%Colore e forma:SolidPeso molecolare:255.32(Rac)-Benpyrine
CAS:(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.Formula:C16H16N6OPurezza:98.44%Colore e forma:SolidPeso molecolare:308.34Ref: TM-T8692
1mg46,00€2mg62,00€5mg92,00€10mg152,00€25mg295,00€50mg442,00€100mg620,00€200mg875,00€1mL*10mM (DMSO)105,00€Myrislignan
CAS:Myrislignan exhibits anti-inflammatory, anti-cancer properties, hinders NF-κB pathway, curbs A549 cell growth, and triggers apoptosis and cell cycle arrest.
Formula:C21H26O6Purezza:98.77% - 99.41%Colore e forma:SolidPeso molecolare:374.43Parthenolide
CAS:Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.Formula:C15H20O3Purezza:98.19% - 99.46%Colore e forma:White To Pale Yellow Crystalline PowderPeso molecolare:248.32
