NF-κB
Il fattore nucleare kappa-light-chain-enhancer delle cellule B attivate (NF-κB) è un fattore di trascrizione che regola l'espressione di geni coinvolti nelle risposte immunitarie, nell'infiammazione, nella sopravvivenza cellulare e nella proliferazione. NF-κB viene attivato in risposta a vari stimoli, tra cui citochine, agenti patogeni e segnali di stress. La disregolazione della segnalazione di NF-κB è associata a malattie infiammatorie croniche, cancro e disturbi autoimmuni. Presso CymitQuimica, offriamo una selezione completa di modulatori della via NF-κB per supportare la tua ricerca su infiammazione, oncologia e regolazione immunitaria.
Trovati 407 prodotti di "NF-κB"
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IRAK-4 protein kinase inhibitor 2
CAS:IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).Formula:C14H10N4O3Purezza:99.5%Colore e forma:SolidPeso molecolare:282.25GSK8612
CAS:GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .Formula:C17H17BrF3N7O2SPurezza:99.68% - 99.99%Colore e forma:SolidPeso molecolare:520.33NF-κB-IN-1
CAS:NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathwayFormula:C31H30O8Purezza:99.03%Colore e forma:SolidPeso molecolare:530.57Ref: TM-T9105
1mg166,00€5mg341,00€10mg550,00€25mg898,00€50mg1.216,00€100mg1.644,00€1mL*10mM (DMSO)398,00€Laquinimod
CAS:Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral
Formula:C19H17ClN2O3Purezza:98.42% - 98.84%Colore e forma:SolidPeso molecolare:356.8(E/Z)-IT-603
CAS:(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.Formula:C11H9BrN2O3SPurezza:99.35%Colore e forma:SolidPeso molecolare:329.17Ref: TM-T8799
1mg56,00€5mg119,00€10mg192,00€25mg356,00€50mg565,00€100mg802,00€200mg1.099,00€1mL*10mM (DMSO)133,00€Sulindac sodium
CAS:Sulindac (sodium) (MK-231) is an NSAID used for arthritis pain, swelling, gout, and as an immunomodulator in CRC therapy.Formula:C20H16FNaO3SColore e forma:SolidPeso molecolare:378.39IMM-H007
CAS:IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFormula:C22H23N5O8Purezza:97.73%Colore e forma:SolidPeso molecolare:485.45Ref: TM-T9010
1mg40,00€5mg96,00€10mg135,00€25mg226,00€50mg320,00€100mg434,00€200mg602,00€1mL*10mM (DMSO)131,00€Theaflavin 3,3′-digallate
CAS:Theaflavin 3,3'-digallate, a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancerFormula:C43H32O20Purezza:98.71% - 99.86%Colore e forma:SolidPeso molecolare:868.70Ref: TM-T5429
1mg87,00€5mg169,00€10mg268,00€25mg462,00€50mg647,00€100mg873,00€200mg1.153,00€1mL*10mM (DMSO)268,00€Ginsenoside Rg6
CAS:Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cellsFormula:C42H70O12Purezza:97.34%Colore e forma:SolidPeso molecolare:767Articaine
CAS:Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-Formula:C13H20N2O3SColore e forma:SolidPeso molecolare:284.37CORM-3
CAS:CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.Formula:C5H4ClNO5RuPurezza:98%Colore e forma:SolidPeso molecolare:294.61anemarsaponin B
CAS:Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activityFormula:C45H74O18Purezza:99.06% - 99.11%Colore e forma:SolidPeso molecolare:903.062,5-Dihydroxyacetophenone
CAS:2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.Formula:C8H8O3Purezza:99.75%Colore e forma:Yellow PowderPeso molecolare:152.152-Hydroxychalcone
CAS:2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.Formula:C15H12O2Purezza:99.6%Colore e forma:SolidPeso molecolare:224.25Indole-3-carbinol
CAS:Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinaseFormula:C9H9NOPurezza:98.59% - >99.99%Colore e forma:SolidPeso molecolare:147.17Ginsenoside Rd
CAS:Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.Formula:C48H82O18Purezza:99.13% - 99.92%Colore e forma:SolidPeso molecolare:947.15Ref: TM-T2878
1mg37,00€5mg71,00€10mg99,00€25mg170,00€50mg260,00€100mg394,00€200mg570,00€1mL*10mM (DMSO)124,00€Aristolochic acid A
CAS:Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort family of plants.Formula:C17H11NO7Purezza:99.85% - 99.97%Colore e forma:Yellow PowderPeso molecolare:341.27Isoquercetin
CAS:1.Formula:C21H20O12Purezza:98.08% - 99.76%Colore e forma:SolidPeso molecolare:464.38Ref: TM-T5S0754
5mg46,00€10mg58,00€25mg92,00€50mg137,00€100mg200,00€200mg295,00€1mL*10mM (DMSO)49,00€Dehydroevodiamine
CAS:Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressantFormula:C19H15N3OPurezza:99.54%Colore e forma:SolidPeso molecolare:301.34JH-X-119-01
CAS:JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1.Formula:C25H20N6O3Purezza:98.42%Colore e forma:SolidPeso molecolare:452.46Ref: TM-T9203
1mg66,00€2mg96,00€5mg144,00€10mg210,00€25mg376,00€50mg562,00€100mg780,00€1mL*10mM (DMSO)159,00€
