NF-κB
Il fattore nucleare kappa-light-chain-enhancer delle cellule B attivate (NF-κB) è un fattore di trascrizione che regola l'espressione di geni coinvolti nelle risposte immunitarie, nell'infiammazione, nella sopravvivenza cellulare e nella proliferazione. NF-κB viene attivato in risposta a vari stimoli, tra cui citochine, agenti patogeni e segnali di stress. La disregolazione della segnalazione di NF-κB è associata a malattie infiammatorie croniche, cancro e disturbi autoimmuni. Presso CymitQuimica, offriamo una selezione completa di modulatori della via NF-κB per supportare la tua ricerca su infiammazione, oncologia e regolazione immunitaria.
Trovati 426 prodotti di "NF-κB"
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Indacaterol maleate
CAS:Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.Formula:C28H32N2O7Purezza:99.03% - 99.67%Colore e forma:SolidPeso molecolare:508.56Methylthiouracil
CAS:Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.Formula:C5H6N2OSPurezza:99.89% - >99.99%Colore e forma:Crystals Saturated Aqueous Solution Is Neutral Or Slightly Acidic (Ntp 1992)Peso molecolare:142.18Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Formula:C18H14N4O5SPurezza:98.00% - 99.28%Colore e forma:Minute Brownish-Yellow CrystalsPeso molecolare:398.39Mevastatin
CAS:Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.Formula:C23H34O5Purezza:99.12%Colore e forma:White-Yellowish To Yellow Powder Solid PowderPeso molecolare:390.51Theophylline monohydrate
CAS:Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calciumFormula:C7H8N4O2·H2OPurezza:99.78%Colore e forma:SolidPeso molecolare:198.18Erdosteine
CAS:Erdosteine (RV 144), a mucolytic thiol, modulates mucus and aids expectoration, reduces cough, and protects lungs from smoke damage.Formula:C8H11NO4S2Purezza:99.65% - 99.94%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:249.31Dihydroartemisinin
CAS:Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!Formula:C15H24O5Purezza:98% - 99.41%Colore e forma:White SolidPeso molecolare:284.35Aspirin
CAS:Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.Formula:C9H8O4Purezza:99.78% - 99.91%Colore e forma:White Solid CrystallinePeso molecolare:180.16Sulindac
CAS:Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.Formula:C20H17FO3SPurezza:99.09% - 99.15%Colore e forma:Yellow SolidPeso molecolare:356.41Mangiferin
CAS:Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.Formula:C19H18O11Purezza:99.78% - 99.86%Colore e forma:Light Yellow PowderPeso molecolare:422.34Sinomenine hydrochloride
CAS:Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.Formula:C19H24ClNO4Purezza:99.43%Colore e forma:SolidPeso molecolare:365.85DMAPT
CAS:DMAPT is a water-soluble PTL analogue, orally active NF-κB inhibitor with 1.7 μM LD50 in acute myeloid leukemia cells.Formula:C17H27NO3Purezza:99.91%Colore e forma:SolidPeso molecolare:293.4Lidocaine Hydrochloride hydrate
CAS:Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Formula:C14H22N2O·HCl·H2OPurezza:99.95%Colore e forma:SolidPeso molecolare:288.82Nimbolide
CAS:Nimbolide, from neem, inhibits CDK4/6, NF-κB, Wnt, PI3K-Akt, MAPK, JAK-STAT pathways and induces apoptosis.Formula:C27H30O7Purezza:95.84% - 99.4%Colore e forma:SolidPeso molecolare:466.52Ref: TM-T16324
1mg71,00€5mg177,00€10mg305,00€25mg628,00€50mg867,00€100mg1.169,00€200mg1.520,00€1mL*10mM (DMSO)190,00€GSK3145095
CAS:GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential immunomodulatory activities and antineoplastic.Formula:C20H17F2N5O2Purezza:99.50%Colore e forma:SolidPeso molecolare:397.38Ref: TM-T15437
1mg96,00€5mg246,00€10mg344,00€25mg553,00€50mg727,00€100mg938,00€1mL*10mM (DMSO)240,00€Sodium salicylate
CAS:<p>Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.</p>Formula:C7H5NaO3Purezza:99.36% - 99.92%Colore e forma:White Solid AmorphousPeso molecolare:160.11Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFormula:C21H18O11Purezza:90.08% - 99.32%Colore e forma:Yellow PowderPeso molecolare:446.36Ref: TM-T2775
1g85,00€2g107,00€5g160,00€50mg37,00€100mg52,00€200mg51,00€500mg58,00€1mL*10mM (DMSO)52,00€CDDO-dhTFEA
CAS:CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor.Formula:C33H45F3N2O3Purezza:95.61% - 99.59%Colore e forma:SolidPeso molecolare:574.72Ref: TM-T13604
1mg70,00€2mg92,00€5mg153,00€10mg255,00€25mg512,00€50mg738,00€100mg1.035,00€500mg2.062,00€1mL*10mM (DMSO)187,00€DRI-C21045
CAS:Dri-c21045 inhibits NF-kB (IC50=17.1μM) and B cell proliferation (IC50=4.5μM), selectively blocking CD40-CD40L interaction (IC50=0.17μM).Formula:C32H24N2O7SPurezza:97.20%Colore e forma:SolidPeso molecolare:580.61Asatone
CAS:Asatone from Radix et Rhizoma Asari has anti-inflammatory properties, acting on NF-κB and suppressing p-MAPK pathways (ERK, JNK, p38).Formula:C24H32O8Purezza:99.84% - 99.92%Colore e forma:SolidPeso molecolare:448.51Ref: TM-T10383
1mg81,00€5mg170,00€10mg274,00€25mg465,00€50mg663,00€100mg919,00€200mg1.216,00€1mL*10mM (DMSO)188,00€
