NF-κB
Il fattore nucleare kappa-light-chain-enhancer delle cellule B attivate (NF-κB) è un fattore di trascrizione che regola l'espressione di geni coinvolti nelle risposte immunitarie, nell'infiammazione, nella sopravvivenza cellulare e nella proliferazione. NF-κB viene attivato in risposta a vari stimoli, tra cui citochine, agenti patogeni e segnali di stress. La disregolazione della segnalazione di NF-κB è associata a malattie infiammatorie croniche, cancro e disturbi autoimmuni. Presso CymitQuimica, offriamo una selezione completa di modulatori della via NF-κB per supportare la tua ricerca su infiammazione, oncologia e regolazione immunitaria.
Trovati 414 prodotti di "NF-κB"
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Licoagrochalcone C
CAS:Licoagrochalcone C, a flavonoid, inhibits NF-κB and NO production effectively.Formula:C21H22O5Colore e forma:SolidPeso molecolare:354.4Anti-inflammatory agent 7
Anti-inflammatory Agent 7 suppresses proinflammatory cytokines by hindering the NF-κB/MAPK signaling pathway in both LPS-treated RAW 264.7 cells and mice.Formula:C36H40N4O9Colore e forma:SolidPeso molecolare:672.72NF-κB-IN-9
NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dualFormula:C62H50N4O4SColore e forma:SolidPeso molecolare:947.15Ginger extract
CAS:Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).
Colore e forma:SolidMurrayafoline A
CAS:Murrayafoline A is a useful organic compound for research related to life sciences. The catalog number is T124835 and the CAS number is 4532-33-6.Formula:C14H13NOColore e forma:SolidPeso molecolare:211.264Antidesmone
CAS:Antidesmone from Ajuga decumbens inhibits acute lung injury by modulating MAPK and NF-κB.Formula:C19H29NO3Purezza:98%Colore e forma:SolidPeso molecolare:319.443-(2-Hydroxyethyl) thio withaferin A
3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.Formula:C30H44O7SColore e forma:SolidPeso molecolare:548.73IKKγ NBD Inhibitory Peptide
CAS:A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF
Formula:C170H259N49O42S1Purezza:98%Colore e forma:SolidPeso molecolare:3693.3PS 1145 dihydrochloride
CAS:IκB kinase (IKK) inhibitorFormula:C17H13Cl3N4OPurezza:98%Colore e forma:SolidPeso molecolare:395.67Nasunin
CAS:Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.Formula:C42H47ClO23Colore e forma:SolidPeso molecolare:955.26MRT67307
CAS:Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.Formula:C26H36N6O2Purezza:99.25% - 99.84%Colore e forma:SolidPeso molecolare:464.6CAY10512
CAS:CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.Formula:C15H13FOColore e forma:SolidPeso molecolare:228.266Transcription Factor-Targeted Compound Library
Well-chosen xnum compounds with unique structures targeting transcription factor;Colore e forma:Odour SolidRef: TM-L1380
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaNF-κΒ activator 1
CAS:NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.Formula:C16H11FN2O2SPurezza:99.58%Colore e forma:SolidPeso molecolare:314.33Ref: TM-T39965
1mg95,00€5mg202,00€10mg329,00€25mg560,00€50mg800,00€100mg1.103,00€500mg2.213,00€1mL*10mM (DMSO)224,00€R1-ICR-5
CAS:R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.Formula:C54H70N8O7S2Colore e forma:SolidPeso molecolare:1007.3112-Oxo phytodienoic acid
CAS:12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.
Formula:C18H28O3Purezza:98%Colore e forma:SolidPeso molecolare:292.41SN50M
CAS:SN50M (NF-κB Control) is a synthetic peptide containing a hydrophobic region and mutant nuclear localization sequences that can enter cells.Formula:C123H215N33O30SColore e forma:SolidPeso molecolare:2668.29Lemnalol
CAS:Lemnalol, from Lemnalia cervicorni, has anti-inflammatory and analgesic properties.Formula:C15H24OPurezza:98%Colore e forma:SolidPeso molecolare:220.35Anti-inflammatory agent 48
Anti-inflammatory agent 48 functions by inhibiting the NF-κB signaling pathway and activating HO-1 expression, characterizing its role as an anti-inflammatoryFormula:C24H21Cl2NO3Purezza:98%Colore e forma:SolidPeso molecolare:442.33NF-κB-IN-12
NF-κB-IN-12 (compound 3h) serves as a potent inhibitor of NF-κB, exhibiting an IC50 value of 1.02 μM. It is applicable for research in acute lung injury [1].Formula:C30H26N6O5SPurezza:98%Colore e forma:SolidPeso molecolare:582.63
