CXCR
I CXCR sono una sottoclasse di GPCR che si legano alle chemochine, piccole proteine segnale che guidano il movimento delle cellule immunitarie verso i siti di infiammazione, infezione o lesione. I CXCR svolgono ruoli cruciali nelle risposte immunitarie, nella metastasi del cancro e nelle malattie infiammatorie. I modulatori dei CXCR sono studiati per il loro potenziale nel trattamento delle malattie autoimmuni, del cancro e delle condizioni infiammatorie croniche. Presso CymitQuimica, offriamo una gamma di modulatori di CXCR di alta qualità per supportare la tua ricerca in immunologia, oncologia e infiammazione.
Trovati 155 prodotti di "CXCR"
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JMS-17-2
CAS:JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).Formula:C25H26ClN3OPurezza:98.7% - 99.44%Colore e forma:SolidPeso molecolare:419.95AMD 3465 hexahydrobromide
CAS:AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.Formula:C24H44Br6N6Purezza:99.39%Colore e forma:SolidPeso molecolare:896.07MSX-122
CAS:MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM).Formula:C16H16N6Purezza:98.31% - 98.94%Colore e forma:SolidPeso molecolare:292.34SRT3109
CAS:SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.Formula:C18H23F2N5O4S2Purezza:99.65% - 99.92%Colore e forma:SolidPeso molecolare:475.53SX-682
CAS:SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.Formula:C19H14BF4N3O4SPurezza:98.19% - 99.61%Colore e forma:SolidPeso molecolare:467.2Baohuoside I
CAS:Baohuoside I (Icariside-II) is a component of Epimedium koreanum, exhibits anti-inflammatory activity and anti-osteoporosis activities.Formula:C27H30O10Purezza:97.64% - 98.14%Colore e forma:SolidPeso molecolare:514.52Danirixin
CAS:<p>Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).</p>Formula:C19H21ClFN3O4SPurezza:99.78% - >99.99%Colore e forma:SolidPeso molecolare:441.9Mavorixafor trihydrochloride
CAS:Mavorixafor trihydrochloride blocks CXCR4 (IC50: 13 nM) and suppresses T-tropic HIV-1 replication (IC50: 1-9 nM). It's orally active.Formula:C21H30Cl3N5Purezza:98.00%Colore e forma:SolidPeso molecolare:458.86Nicotinamide N-oxide
CAS:Nicotinamide N-oxide, a metabolite of nicotinamide and precursor to NAD+, is reduced by liver enzyme xanthine oxidase.Formula:C6H6N2O2Purezza:99.66% - 99.9%Colore e forma:SolidPeso molecolare:138.12Elubrixin HCl
CAS:Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist.Formula:C17H18Cl3FN4O4SColore e forma:SolidPeso molecolare:499.77WZ811
CAS:<p>WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).</p>Formula:C18H18N4Purezza:99.42% - ≥95%Colore e forma:SolidPeso molecolare:290.36Plerixafor octahydrochloride
CAS:Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.Formula:C28H62Cl8N8Purezza:98.01% - 99.79%Colore e forma:SolidPeso molecolare:794.46MSX-127
CAS:MSX-127 elicites positive response in peptide CXCR4.Formula:C16H24N2O4Purezza:98.43%Colore e forma:SolidPeso molecolare:308.37ATI-2341 acetate(1337878-62-2 free base)
ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13.Formula:C106H182N26O27S2Purezza:97.14%Colore e forma:SolidPeso molecolare:2316.87FC131 TFA (606968-52-9 free base)
CAS:FC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hivFormula:C38H48F3N11O8Purezza:99.39% - 99.67%Colore e forma:SolidPeso molecolare:843.85USL311
CAS:USL311 blocks CXCR4/SDF-1 interaction, inhibits tumor cell growth and migration.Formula:C24H34N6OPurezza:98.46% - 99.56%Colore e forma:SolidPeso molecolare:422.57CTCE 9908 acetate
CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer cells.Formula:C88H151N27O25Purezza:98.47%Colore e forma:SolidPeso molecolare:1987.31SB-265610
CAS:<p>SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist.</p>Formula:C14H9BrN6OPurezza:99.5%Colore e forma:SolidPeso molecolare:357.16Navarixin
CAS:Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophilFormula:C21H23N3O5Purezza:98% - 99.51%Colore e forma:SolidPeso molecolare:397.42SB225002
CAS:SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.Formula:C13H10BrN3O4Purezza:98.16% - 99.85%Colore e forma:SolidPeso molecolare:352.14
