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CXCR

CXCR

I CXCR sono una sottoclasse di GPCR che si legano alle chemochine, piccole proteine segnale che guidano il movimento delle cellule immunitarie verso i siti di infiammazione, infezione o lesione. I CXCR svolgono ruoli cruciali nelle risposte immunitarie, nella metastasi del cancro e nelle malattie infiammatorie. I modulatori dei CXCR sono studiati per il loro potenziale nel trattamento delle malattie autoimmuni, del cancro e delle condizioni infiammatorie croniche. Presso CymitQuimica, offriamo una gamma di modulatori di CXCR di alta qualità per supportare la tua ricerca in immunologia, oncologia e infiammazione.

Trovati 155 prodotti di "CXCR"

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  • CXCR4 modulator-1
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    CXCR4 modulator-1

    CAS:
    CXCR4 modulator-1 (ZINC72372983) is potent (EC50=100nM) with uses in anti-inflammatory, anticancer, and anti-HIV research.
    Formula:C23H27N5O2
    Colore e forma:Solid
    Peso molecolare:405.49

    Ref: TM-T62007

  • Logo CymitQuimica
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    CXCR4 antagonist 3

    CXCR4 antagonist 3, aka compound 12a, has 11 nM IC50, shares TIQ15 traits, and is promising in HIV research.
    Formula:C22H31N5
    Colore e forma:Solid
    Peso molecolare:365.52

    Ref: TM-T61409

  • CCX662
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    CCX662

    CAS:
    CCX662 is a CXCR7 antagonist. It inhibits the binding of 125I-CXCL12 to CXCR7 with an IC50 of 9 nM. This compound is suitable for use in cancer research.
    Formula:C28H37N5O4S
    Colore e forma:Solid
    Peso molecolare:539.69

    Ref: TM-T201863

  • SCH 563705
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    SCH 563705

    CAS:
    SCH 563705 is a CXCR2 and CXCR1 antagonist used in the study of acute respiratory syndrome, chronic obstructive pulmonary disease, and inflammation.
    Formula:C23H27N3O5
    Purezza:98.03%
    Colore e forma:Solid
    Peso molecolare:425.48

    Ref: TM-T16864

  • SLW131
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    SLW131

    CAS:
    <p>SLW131 (Compound 10) is a CCR7 antagonist with strong affinity, showing a Ki of 9.85 nM. It inhibits CCL19-induced Go protein activation with an IC50 of 29.4 μM and β-arrestin2 recruitment with an IC50 of 6.0 μM. SLW131 also suppresses CCL19-induced morphological changes in primary BMDC cells and CCR7-mediated migration of mouse CD4+ T cells.</p>
    Formula:C21H27N5O5S
    Colore e forma:Solid
    Peso molecolare:461.535

    Ref: TM-T205065

  • ACT-777991
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    ACT-777991

    CAS:
    ACT-777991: oral CXCR3 blocker, stable in microsomes/hepatocytes, inhibits T-cell migration to CXCL11.
    Formula:C20H20F6N8O2S
    Colore e forma:Solid
    Peso molecolare:550.48

    Ref: TM-T73148

  • Logo CymitQuimica
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    CXCR2 antagonist 7

    <p>CXCR2 antagonist 7 is a powerful blocker with IC50s: 0.044 μM for binding, 0.66 μM for calcium mobilization.</p>
    Formula:C14H14F2N6OS
    Colore e forma:Solid
    Peso molecolare:352.36

    Ref: TM-T61236

  • CXCR7 modulator 2
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    CXCR7 modulator 2

    CAS:
    CXCR7 modulator 2 is a 7-type C-X-C chemokine receptor (CXCR7) modulator with a Ki of 13 nM.
    Formula:C29H42N6O3
    Colore e forma:Solid
    Peso molecolare:522.68

    Ref: TM-T10907

  • CXCR4 antagonist 10
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    CXCR4 antagonist 10

    CAS:
    CXCR4 antagonist10 (compound 21) is an effective CXCR4 inhibitor with an IC50 value of 7.8 nM. It plays a significant role in cancer research.
    Formula:C18H18N4O4
    Colore e forma:Solid
    Peso molecolare:354.36

    Ref: TM-T200568

  • CXCR7 antagonist-1 hydrochloride
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    CXCR7 antagonist-1 hydrochloride

    CAS:
    CXCR7 antagonist-1 hydrochloride blocks SDF-1 and I-TAC from CXCR7; may prevent cancer and inflammation.
    Formula:C21H20ClFN6O
    Colore e forma:Solid
    Peso molecolare:426.87

    Ref: TM-T62325

  • Logo CymitQuimica
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    CXCR2 antagonist 6

    CXCR2 antagonist 6: strong CXCR2 affinity (IC50=0.044 μM), hinders calcium mobilization (IC50=0.66 μM).
    Formula:C17H16F2N4OS
    Colore e forma:Solid
    Peso molecolare:362.4

    Ref: TM-T61359

  • (R)-SCH 546738
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    (R)-SCH 546738

    CAS:
    (R)-SCH 546738, the R-isomer of SCH 546738, is a non-competitive, orally active antagonist targeting the CXCR3 receptor, exhibiting a K_i of 0.4 nM for the human CXCR3 receptor.
    Formula:C23H31Cl2N7O
    Colore e forma:Solid
    Peso molecolare:492.45

    Ref: TM-T200169

  • Logo CymitQuimica
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    CXCR2 antagonist 4

    CXCR2 antagonist 4 inhibits CXCR2 (IC50: 0.13 μM) and CXCL8-induced calcium rise (IC50: 27 μM), promising for cancer research.
    Formula:C15H14F2N4OS2
    Colore e forma:Solid
    Peso molecolare:368.42

    Ref: TM-T61447

  • VUF11207 trifluoroacetate salt
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    VUF11207 trifluoroacetate salt

    CAS:
    VUF11207 trifluoroacetate salt is a useful organic compound for research related to life sciences. The catalog number is T66657 and the CAS number is 1378524-41-4.
    Formula:C29H36F4N2O6
    Colore e forma:Solid
    Peso molecolare:584.609

    Ref: TM-T66657

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  • CXCR4-IN-1
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    CXCR4-IN-1

    CAS:
    <p>CXCR4-IN-1 (Example C5), with an IC50 of 20 nM, is a potent inhibitor of CXCR4, applicable for the research of various conditions such as cancer, HIV, diabetic</p>
    Formula:C23H32N6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:392.54

    Ref: TM-T79059

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