STAT

HODHBt is a STAT5-SUMO protein-protein interaction inhibitor.

Golotimod is an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, …

Fludarabine is a nucleic acid synthesis Inhibitor and a STAT1 activation inhibitor.

Diosgenin is a spirostan found in DIOSCOREA and other plants. It has favorable effects in …

1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates …

HJC0152 is a signal transducer and activator of transcription 3 (STAT3) inhibitor.

CASIN is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).

inS3-54A18 is a potent inhibitor of STAT3. It has anti-cancer properties.

ML116 is a potent and selective STAT3 inhibitor.

Golotimod hydrochloride (SCV 07 hydrochloride), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy …

Cryptotanshinone, a STAT3 inhibitor (IC50: 4.6 μM) in a cell-free assay, strongly inhibits phosphorylation of …

SI-109 is a potent inhibitor of STAT3 SH2 domain (Ki=9 nM),and with antitumor activity.

2-NP is a STAT1 enhancer.

Homoharringtonine is an alkaloid inhibitor of protein synthesis with activity in myeloid malignancies. It might …

AS1517499 is a potent STAT6 inhibitor with IC50 of 21 nM

CMD178 (TFA) is a lead peptide that consistently reduces the expression of Foxp3 and STAT5 …

STAT3-IN-1 selective and orally active inhibitor of STAT3(in HT29 and MDA-MB 231 cells, with IC50 …

STAT3-IN-3 is a potent and selective signal transducer inhibitor and transcription 3 (STAT3) activator.

Artesunate is part of the artemisinin group of drugs that treat malaria. It is a …

1. Tectochrysin has antioxidant effect. 2. Tectochrysin is promising inhibitors for the reversal of ABCG2-mediated …

Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 …

C188-9 is a Stat3 inhibitor with an IC50 of 4-7 μM.

Corylin is a major bioactive compound isolated from Psoralea corylifolia L; it has the activity …

SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).

SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor.

Golotimod (TFA), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, …

1. Morusin possesses antitumor effects of cell lines including HT-29, A549, MCF-7, and MDA-MB-231, through …

Ascochlorin (Ilicicolin D), an isoprenoid antibiotic, mediates its anti-tumor effects predominantly through the suppression of …

Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized …

Nifuroxazide is an orally available and cell-permeable nitrofuran-based antidiarrheal agent. It has the inhibitory effect …

BP-1-102 is an orally active, effective and specific STAT3 inhibitor. BP-1-102 binds Stat3 (Kd: 504 …

Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± …

Niclosamide(BAY2353) is used to treat most tapeworm infections by inhibiting DNA replication.

Napabucasin is an orally available Stat3 and Y cell stemness inhibitor.

Eupalinolide I is a natural product from Eupatorium lindleyanum.

Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b …

RSVA 405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor

S3I-201 is a selective Stat3 inhibitor (IC50: 86±33 μM) and low effect towards STAT1/5.

1. Vitexicarpin can significantly reduce vascular inflammation, through inhibition of ROS-NF-κB pathway in vascular endothelial …

SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib. SC-1 potently inhibits …

HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.

ENMD-119 is a 2-methoxyestradiol analog with antiproliferative and antiangiogenic activity. It is suitable for inhibiting …

Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide is a …

STAT5 Inhibitor is a cell-permeable inhibitor which suppresses Stat5 via binding to the SH2 domain.

STA-21 is a selective STAT3 inhibitor.

Alantolactone(Alant camphor), a sesquiterpene lactone, has potential activity against triple-negative breast Y MDA-MB-231 cells by …

Stattic is a small molecule inhibitor of STAT3. It selectively inhibits STAT3 activation, dimerization, and …

ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of …