STAT
Le proteine STAT sono componenti critici della via di segnalazione JAK/STAT, che trasmette segnali extracellulari da citochine e fattori di crescita al nucleo cellulare, influenzando l'espressione genica. Le proteine STAT sono coinvolte nella regolazione delle risposte immunitarie, della crescita cellulare, della differenziazione e della sopravvivenza. La disregolazione della segnalazione STAT è implicata in varie malattie, tra cui cancro, disturbi autoimmuni e infiammazione cronica. Presso CymitQuimica, offriamo una gamma completa di modulatori della via STAT per supportare la tua ricerca sulla trasduzione del segnale, immunologia e sviluppo terapeutico.
Trovati 98 prodotti di "STAT"
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AS1517499
CAS:AS1517499 is a blood-brain barrier permeable inhibitor of STAT6 phosphorylation (IC50= 21 nM). High-Quality, Low-Cost!Formula:C20H20ClN5O2Purezza:98.27% - 99.3%Colore e forma:SolidPeso molecolare:397.86BD750
CAS:<p>BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in</p>Formula:C14H13N3OSPurezza:99.02%Colore e forma:SolidPeso molecolare:271.34Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formula:C40H52O4Purezza:95.1% - 99.79%Colore e forma:Needles From Acetone/Light Petroleum SolidPeso molecolare:596.84AS1810722
CAS:AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM.Formula:C25H25F2N7OPurezza:99.13%Colore e forma:SolidPeso molecolare:477.511-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS:<p>SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.</p>Formula:C21H13ClF3N3O2Purezza:99.41%Colore e forma:SolidPeso molecolare:431.8Atractylenolide I
CAS:Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Formula:C15H18O2Purezza:97.55% - 99.92%Colore e forma:SolidPeso molecolare:230.3C188-9
CAS:C188-9 (TTI-101) is a Stat3 inhibitor with an IC50 of 4-7 μM.Formula:C27H21NO5SPurezza:98.07% - >99.99%Colore e forma:SolidPeso molecolare:471.52Casticin
CAS:Casticin combats vascular inflammation by blocking ROS-NF-κB and could lead in prostate cancer treatment.Formula:C19H18O8Purezza:99.37% - ≥95%Colore e forma:SolidPeso molecolare:374.34Fraxinellone
CAS:<p>1.</p>Formula:C14H16O3Purezza:99.35% - 99.92%Colore e forma:SolidPeso molecolare:232.27AG490
CAS:AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Formula:C17H14N2O3Purezza:98.6% - 99.85%Colore e forma:Yellow SolidPeso molecolare:294.3Alantolactone
CAS:Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.Cost-effective and quality-assured.Formula:C15H20O2Purezza:99.02% - 99.66%Colore e forma:Crystalline PowderPeso molecolare:232.32Angoline
CAS:<p>Angoline hydrochloride: IL6/STAT3 inhibitor, IC50: 11.56 μM, blocks STAT3 phosphorylation and cancer cell growth.</p>Formula:C22H21NO5Purezza:99.43% - 99.96%Colore e forma:SolidPeso molecolare:379.41Mogrol
CAS:Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.Formula:C30H52O4Purezza:99.85% - 99.90%Colore e forma:SolidPeso molecolare:476.73Colivelin
CAS:<p>Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).</p>Formula:C119H206N32O35Purezza:96.56%Colore e forma:SolidPeso molecolare:2645.1Garcinone D
CAS:<p>Garcinone D is cytotoxic to CEM-SS cells (IC50=3.2 µg/ml), inhibits aromatase and p65 activation (IC50=3.2 µM).</p>Formula:C24H28O7Purezza:99.94%Colore e forma:SolidPeso molecolare:428.47Triacetylresveratrol
CAS:<p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>Formula:C20H18O6Purezza:99.81%Colore e forma:Off White PowderPeso molecolare:354.35Stafia-1
CAS:<p>Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.</p>Formula:C24H27O10PPurezza:98.08%Colore e forma:SolidPeso molecolare:506.44Ochromycinone
CAS:<p>Ochromycinone (STA 21) is a selective STAT3 inhibitor.</p>Formula:C19H14O4Purezza:99.21%Colore e forma:SolidPeso molecolare:306.31Panaxadiol
CAS:<p>Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.</p>Formula:C30H52O3Purezza:98% - 99.9%Colore e forma:SolidPeso molecolare:460.73
