cAMP
cAMP è un secondo messaggero importante in molti processi biologici, inclusa la regolazione del metabolismo, l'espressione genica e la crescita cellulare. Nella via di segnalazione MAPK, cAMP può modulare l'attività di diverse chinasi, inclusa la PKA, che a sua volta influenza la cascata MAPK. La disregolazione della segnalazione di cAMP è implicata in varie malattie, tra cui il cancro e i disturbi cardiovascolari. Presso CymitQuimica, offriamo una varietà di modulatori di cAMP per supportare la tua ricerca sulla trasduzione del segnale, il metabolismo e la patologia delle malattie.
Trovati 47 prodotti di "cAMP"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
HJC0197
CAS:HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.Formula:C19H21N3OSPurezza:98.05%Colore e forma:SolidPeso molecolare:339.45Bithionol
CAS:Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential toFormula:C12H6Cl4O2SPurezza:99.04%Colore e forma:White Or Grayish-White Crystalline Powder Phenolic Odor (Ntp 1992)Peso molecolare:356.05CE3F4
CAS:CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1; IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively).Formula:C11H10Br2FNOPurezza:97.15% - 98.06%Colore e forma:SolidPeso molecolare:351.01Bucladesine sodium
CAS:<p>Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties.</p>Formula:C18H23N5NaO8PPurezza:96.56% - 99.76%Colore e forma:White PowderPeso molecolare:491.37A-3 hydrochloride
CAS:<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Formula:C12H14Cl2N2O2SPurezza:99.32%Colore e forma:SolidPeso molecolare:321.22ESI-05
CAS:ESI-05 (NSC-116966) is a specific 0.4 μM IC50 EPAC2 antagonist that blocks cAMP-induced EPAC2 and Rap1 activation.Formula:C16H18O2SPurezza:97.22%Colore e forma:SolidPeso molecolare:274.38JNJ-39758979
CAS:<p>JNJ-39758979: selective H4 receptor antagonist, Kis 12.5/5.3/25 nM (human/mouse/monkey), blocks histamine cAMP inhibition (pA2 7.9).</p>Formula:C11H19N5Purezza:98.33% - 99.62%Colore e forma:SolidPeso molecolare:221.3MR-L2
CAS:MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).Formula:C19H16Cl3FN4OPurezza:98.09% - 98.94%Colore e forma:SolidPeso molecolare:441.71Mirabegron
CAS:<p>Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome.</p>Formula:C21H24N4O2SPurezza:99.64%Colore e forma:Light Yellow To Yellow SolidPeso molecolare:396.51Adenosine 3'-monophosphate (sodium salt hydrate)
Adenosine 3'-monophosphate (sodium salt hydrate) (3'-AMP) is a nucleotide and cAMP-generating agonist that elevates cAMP levels in NG108-15 cells.Formula:C10H15N5NaO8PColore e forma:SolidPeso molecolare:387.22MRS-1706
CAS:<p>MRS-1706: Ki of 1.39nM for A2B; selective inverse agonist; also affects A2A, A1, A3.</p>Formula:C27H29N5O5Purezza:99.00%Colore e forma:SolidPeso molecolare:503.55BC 11-38
CAS:<p>BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).</p>Formula:C15H16N2OS2Purezza:98.95% - 99.28%Colore e forma:SolidPeso molecolare:304.432-PCCA hydrochloride
CAS:<p>2-PCCA hydrochloride, a racemate, is a potent and selective GPR88 receptor agonist showing inhibition of GPR88-mediated cAMP production in HEK293 cells with an</p>Formula:C30H39Cl2N3OPurezza:97.54% - 99.36%Colore e forma:SoildPeso molecolare:528.56OX04528
CAS:OX04528 is an orally active and potent GPR84 biased agonist.OX04528 inhibits cAMP signaling and may be useful in cancer research.Formula:C16H13F6NO2Purezza:99.74%Colore e forma:SoildPeso molecolare:365.27GLP-1R modulator L7-028
CAS:GLP-1R modulator L7-028 is a variant modulator that enhances affinity for GLP-1 and cAMP signaling.Formula:C24H28N2O3Purezza:98.76% - >99.99%Colore e forma:SolidPeso molecolare:392.49Anti-Cathelicidin/Camp Polyclonal Antibody
Antibody Type: Rabbit Polyclonal<br> Application: ELISA,ICC/IF,IF,IHC-Fr,IHC-P<br> Reactivity: (predicted:Mouse,Rat)Colore e forma:LiquidPeso molecolare:Theoretical: 19 kDa.Taprenepag
CAS:Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM).Formula:C24H22N4O5SPurezza:98.89% - 99.15%Colore e forma:SolidPeso molecolare:478.52PSN 375963
CAS:PSN 375963 (PSN 375963 hydrochloride) hydrochloride is a synthetic agonist of the endogenous ligand for GPR119.Formula:C17H23N3OPurezza:99.63%Colore e forma:SolidPeso molecolare:285.38Ro 20-1724
CAS:Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1Formula:C15H22N2O3Purezza:98.82% - 99.79%Colore e forma:SolidPeso molecolare:278.35(S)-(+)-Rolipram
CAS:(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in theFormula:C16H21NO3Purezza:99.14%Colore e forma:SolidPeso molecolare:275.34Cyclic AMP
CAS:cAMP and vitamin C treat viral myocarditis in children, enhancing cardiac and immune functions.Formula:C10H12N5O6PPurezza:98.01% - >99.99%Colore e forma:SolidPeso molecolare:329.21SAX-187
CAS:SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.Formula:C15H13ClN4O2S2Purezza:97.82% - 98%Colore e forma:SolidPeso molecolare:380.87ESI-09
CAS:ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively.Formula:C16H15ClN4O2Purezza:97.24% - 99.57%Colore e forma:SolidPeso molecolare:330.77Glaucine
CAS:<p>Glaucine: antitussive, antioxidative, antiviral, may fight arthritis, boosts IL-10, hinders breast cancer cell spread by inhibiting MMP-9 and NF-κB.</p>Formula:C21H25NO4Purezza:99.42% - 99.56%Colore e forma:SolidPeso molecolare:355.43RS-25344 hydrochloride
CAS:RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitorFormula:C19H14ClN5O4Purezza:99.25%Colore e forma:SolidPeso molecolare:411.8Setipiprant
CAS:<p>Setipiprant (ACT-129968) is an oral CRTH2 antagonist for asthma/allergy, targeting PGD2-induced inflammation (IC50: 6.0 nM).</p>Formula:C24H19FN2O3Purezza:99.16%Colore e forma:SolidPeso molecolare:402.42Piclamilast
CAS:<p>Piclamilast (RP 73401) is a PDE4 inhibitor.</p>Formula:C18H18Cl2N2O3Purezza:98.28% - 99.57%Colore e forma:SolidPeso molecolare:381.25Pinoresinol 4-O-β-D-glucopyranoside
CAS:<p>(+)-Pinoresinol-β-D-glucoside, also known as (+)-pinor, is a major active lignan furanoid found in Forsythia.</p>Formula:C26H32O11Purezza:99.32% - >99.99%Colore e forma:SolidPeso molecolare:520.53Forskolin
CAS:Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).Formula:C22H34O7Purezza:98.83% - 99.96%Colore e forma:Less Crystalline Solid Colorless Crystalline SolidPeso molecolare:410.50HJC0350
CAS:HJC0350 is an effective and specific EPAC2 inhibitor (IC50: 0.3 μM), and no inhibition of Epac1.Formula:C15H19NO2SPurezza:99.27% - 99.65%Colore e forma:SolidPeso molecolare:277.38Enoximone
CAS:Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.Formula:C12H12N2O2SPurezza:98.53%Colore e forma:SolidPeso molecolare:248.3LY404039
CAS:LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).Formula:C7H9NO6SPurezza:99% - 99.92%Colore e forma:SolidPeso molecolare:235.22Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO)
<p>Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.</p>Colore e forma:Lyophilized PowderPeso molecolare:24.7 kDa (predicted)Uliledlimab
CAS:Uliledlimab, a humanized monoclonal antibody against CD73, reduces extracellular adenosine production and modulates immunosuppressive pathways.Purezza:95% - 95.5% (SDS-PAGE); 95.1% (SEC-HPLC)Colore e forma:LiquidI942
CAS:I942 is a novel, selective ACyclic nucleotide (NCN) EPAC1 agonist that activates exchange proteins to regulate inflammatory gene expression in human umbilicalFormula:C20H19NO4SPurezza:99.86%Colore e forma:SolidPeso molecolare:369.43ESI-08
CAS:<p>ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.</p>Formula:C20H23N3OSPurezza:97.17%Colore e forma:SolidPeso molecolare:353.48EPAC 5376753
CAS:EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 µM in Swiss 3T3 cells.Formula:C15H8Cl2N2O3SPurezza:97.48%Colore e forma:SolidPeso molecolare:367.21Rp-cAMPS sodium
CAS:<p>Rp-cAMPS sodium is a phosphorothioate analog of cAMP, a PKA inhibitor and cAMP antagonist that inhibits cAMP-dependent protein kinases.</p>Formula:C10H11N5NaO5PSPurezza:99.71%Colore e forma:SolidPeso molecolare:367.25KI-7
CAS:KI-7 is an adenosine A2B receptor positive allosteric modulator.Formula:C23H18N2O2Purezza:98.33%Colore e forma:SolidPeso molecolare:354.4UNC0006
CAS:<p>UNC0006 is a β-arrestin-biased dopamine D2 ligand.</p>Formula:C24H29Cl2N3O2Purezza:99.35% - 99.97%Colore e forma:SolidPeso molecolare:462.41Torbafylline
CAS:<p>Torbafylline is a xanthine-based PDE inhibitor reducing protein breakdown via PDE4/cAMP/EPAC/PI3K/Akt in rats with burns, cancer, or sepsis.</p>Formula:C16H26N4O4Purezza:98.66% - 99.13%Colore e forma:SoildPeso molecolare:338.4CJ-42794
CAS:CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4).Formula:C22H17ClFNO4Purezza:99.92%Colore e forma:SolidPeso molecolare:413.83NCGC00229600
CAS:NCGC00229600: Allosteric inverse TSHR agonist; blocks TSH and antibody TSHR activation; for Graves' disease research.Formula:C30H29N3O3Purezza:99.31%Colore e forma:SolidPeso molecolare:479.57CW 008
CAS:CW 008 is an agonist of the cAMP/PKA/CREB pathway, promoting osteogenic differentiation of bone marrow-derived mesenchymal stem cells (MSCs).a PKA activator.Formula:C21H14F2N6O2Purezza:97.39%Colore e forma:SolidPeso molecolare:420.37TP-10
CAS:TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.Formula:C26H19F3N4OPurezza:99.21%Colore e forma:SolidPeso molecolare:460.45LGD-6972
CAS:<p>LGD-6972 is an antagonist of glucagon receptor.</p>Formula:C43H46N2O5SPurezza:98.8% - 99.62%Colore e forma:SolidPeso molecolare:702.9Vidupiprant
CAS:Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma.Formula:C28H27Cl2FN2O6SPurezza:98.88%Colore e forma:SolidPeso molecolare:609.49
